Publications by authors named "Shengkai Ko"

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Anti-influenza drug discovery: identification of an orally bioavailable quinoline derivative through activity- and property-guided lead optimization.
Jiann-Yih Yeh, Mohane Selvaraj Coumar, Hui-Yi Shiao, Ta-Jen Lin, Yen-Chun Lee, Shengkai Ko

ChemMedChem· September 2012

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Identification of BPR3P0128 as an inhibitor of cap-snatching activities of influenza virus.
John T-A Hsu, Jiann-Yih Yeh, Ta-Jen Lin, Mei-Ling Li, Ming-Sian Wu, Shengkai Ko

Antimicrob Agents Chemother· February 2012

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Synthesis and evaluation of the cytotoxicities of tetraindoles: observation that the 5-hydroxy tetraindole (SK228) induces G₂ arrest and apoptosis in human breast cancer cells.
Wen-Shan Li, Chie-Hong Wang, Shengkai Ko, Tzu Ting Chang, Ya Ching Jen

J Med Chem· February 2012

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BPR1K653, a novel Aurora kinase inhibitor, exhibits potent anti-proliferative activity in MDR1 (P-gp170)-mediated multidrug-resistant cancer cells.
Chun Hei Antonio Cheung, Wen-Hsing Lin, John Tsu-An Hsu, Tzyh-Chyuan Hour, Teng-Kuang Yeh, Shengkai Ko

PLoS One· January 2012

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Novel 2-step synthetic indole compound 1,1,3-tri(3-indolyl)cyclohexane inhibits cancer cell growth in lung cancer cells and xenograft models.
Ching-Hsiao Lee, Ching-Fa Yao, Sin-Ming Huang, Shengkai Ko, Yi-Hung Tan

Cancer· August 2008

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An investigation of the reaction of 2-aminobenzaldehyde derivatives with conjugated nitro-olefins: an easy and efficient synthesis of 3-nitro-1,2-dihydroquinolines and 3-nitroquinolines.
Ming-Chung Yan, Zhijay Tu, Chunchi Lin, Shengkai Ko, Jianming Hsu

J Org Chem· March 2004

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