Publications by authors named "Shigeru Yanagi"

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Etomoxir suppresses the expression of PPARγ2 and inhibits the thermogenic gene induction of brown adipocytes through pathways other than β-oxidation inhibition.
Hiroki Shimura, Sota Yamamoto, Isshin Shiiba, Mami Oikawa, Shohei Uchinomiya, Shigeru Yanagi

J Biochem· March 2025

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ER-mitochondria contacts mediate lipid radical transfer via RMDN3/PTPIP51 phosphorylation to reduce mitochondrial oxidative stress.
Isshin Shiiba, Naoki Ito, Hijiri Oshio, Yuto Ishikawa, Takahiro Nagao, Shigeru Yanagi

Nat Commun· February 2025

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Role of immature choroid plexus in the pathology of model mice and human iPSC-derived organoids with autism spectrum disorder.
Motoi Tanabe, Yuga Saito, Ayaka Takasaki, Keita Nakano, Shunta Yamamoto, Shigeru Yanagi

Cell Rep· January 2025

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MITOL deficiency triggers hematopoietic stem cell apoptosis via ER stress response.
Wenjuan Ma, Shah Adil Ishtiyaq Ahmad, Michihiro Hashimoto, Ahad Khalilnezhad, Miho Kataoka, Shigeru Yanagi

EMBO J· February 2024

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Role of Mitochondrial Dynamics in Heart Diseases.
Takeshi Tokuyama, Shigeru Yanagi

Genes (Basel)· September 2023

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Ubiquitin-mediated mitochondrial regulation by MITOL/MARCHF5 at a glance.
Shun Nagashima, Naoki Ito, Isshin Shiiba, Hiroki Shimura, Shigeru Yanagi

J Biochem· December 2022

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Protective roles of MITOL against myocardial senescence and ischemic injury partly via Drp1 regulation.
Takeshi Tokuyama, Hideki Uosaki, Ayumu Sugiura, Gen Nishitai, Keisuke Takeda, Shigeru Yanagi

iScience· July 2022

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MITOL regulates phosphatidic acid-binding activity of RMDN3/PTPIP51.
Naoki Ito, Takara Takahashi, Isshin Shiiba, Shun Nagashima, Ryoko Inatome, Shigeru Yanagi

J Biochem· May 2022

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Mitochondrial Fragmentation Triggers Ineffective Hematopoiesis in Myelodysplastic Syndromes.
Yasushige Aoyagi, Yoshihiro Hayashi, Yuka Harada, Kwangmin Choi, Natsumi Matsunuma, Shigeru Yanagi

Cancer Discov· January 2022

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MITOL/MARCH5 determines the susceptibility of cardiomyocytes to doxorubicin-induced ferroptosis by regulating GSH homeostasis.
Hiroki Kitakata, Jin Endo, Hirokazu Matsushima, Shoichi Yamamoto, Hidehiko Ikura, Shigeru Yanagi

J Mol Cell Cardiol· December 2021

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Potent anti-tumor effects of receptor-retargeted syncytial oncolytic herpes simplex virus.
Takuma Suzuki, Hiroaki Uchida, Tomoko Shibata, Yasuhiko Sasaki, Hitomi Ikeda, Shigeru Yanagi

Mol Ther Oncolytics· September 2021

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Forebrain-specific deficiency of the GTPase CRAG/Centaurin-γ3 leads to immature dentate gyri and hyperactivity in mice.
Shun Nagashima, Naoki Ito, Reiki Kobayashi, Isshin Shiiba, Hiroki Shimura, Shigeru Yanagi

J Biol Chem· August 2021

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Oscillation of Cdc20-APC/C-mediated CAMDI stability is critical for cortical neuron migration.
Shohei Okuda, Mariko Sato, Saho Kato, Shun Nagashima, Ryoko Inatome, Shigeru Yanagi

J Biol Chem· August 2021

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Ubiquitination-dependent and -independent repression of target genes by SETDB1 reveal a context-dependent role for its methyltransferase activity during adipogenesis.
Ji Zhang, Yoshihiro Matsumura, Yuka Kano, Ayano Yoshida, Takeshi Kawamura, Shigeru Yanagi

Genes Cells· July 2021

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Identification of highest neurotoxic amyloid-β plaque type showing reduced contact with astrocytes.
Mikihiro Mitsubori, Keisuke Takeda, Shun Nagashima, Satoshi Ishido, Masaaki Matsuoka, Shigeru Yanagi

Biochem Biophys Res Commun· April 2021

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MITOL promotes cell survival by degrading Parkin during mitophagy.
Isshin Shiiba, Keisuke Takeda, Shun Nagashima, Naoki Ito, Takeshi Tokuyama, Shigeru Yanagi

EMBO Rep· March 2021

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Mitochondrial ubiquitin ligase alleviates Alzheimer's disease pathology via blocking the toxic amyloid-β oligomer generation.
Keisuke Takeda, Aoi Uda, Mikihiro Mitsubori, Shun Nagashima, Hiroko Iwasaki, Shigeru Yanagi

Commun Biol· February 2021

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MITOL dysfunction causes dwarfism with anterior pituitary hypoplasia.
Keigo Matsuno, Shun Nagashima, Isshin Shiiba, Keito Taniwaka, Keisuke Takeda, Shigeru Yanagi

J Biochem· September 2020

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Overview of Mitochondrial E3 Ubiquitin Ligase MITOL/MARCH5 from Molecular Mechanisms to Diseases.
Isshin Shiiba, Keisuke Takeda, Shun Nagashima, Shigeru Yanagi

Int J Mol Sci· May 2020

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CAMDI interacts with the human memory-associated protein KIBRA and regulates AMPAR cell surface expression and cognition.
Toshifumi Fukuda, Shun Nagashima, Ryoko Inatome, Shigeru Yanagi

PLoS One· March 2020

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Mitochondrial Dynamics Regulation in Skin Fibroblasts from Mitochondrial Disease Patients.
Takeshi Tokuyama, Asei Hirai, Isshin Shiiba, Naoki Ito, Keigo Matsuno, Shigeru Yanagi

Biomolecules· March 2020

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Critical role of CRAG, a splicing variant of centaurin-γ3/AGAP3, in ELK1-dependent SRF activation at PML bodies.
Shun Nagashima, Keisuke Takeda, Isshin Shiiba, Mizuho Higashi, Toshifumi Fukuda, Shigeru Yanagi

Sci Rep· December 2019

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Explant Culture of the Embryonic Mouse Spinal Cord and Gene Transfer by Electroporation.
Mariko Kinoshita-Kawada, Hiroshi Hasegawa, Tsunaki Hongu, Shigeru Yanagi, Yasunori Kanaho

Bio Protoc· September 2019

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Mitochondrial retrograde signaling to the endoplasmic-reticulum regulates unfolded protein responses.
Keisuke Takeda, Shigeru Yanagi

Mol Cell Oncol· September 2019

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MITOL deletion in the brain impairs mitochondrial structure and ER tethering leading to oxidative stress.
Shun Nagashima, Keisuke Takeda, Nobuhiko Ohno, Satoshi Ishido, Motohide Aoki, Shigeru Yanagi

Life Sci Alliance· August 2019

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