Publications by authors named "Shih-Chin Cheng"

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Inhibiting NEDD4 in triple-negative breast cancer cells reprograms tumor immune microenvironment via the β-TrCP/YAP/ECM axis.
Nan Su, Wenhua Lian, Baoding Zhang, Yuan Tian, Linying Li, Shih-Chin Cheng

Cell Rep Med· October 2025

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Piezo1 senses hyphae and initiates host defense against pathogenic fungi.
Yiran Shi, Bingying Yang, Yueyue Linghu, Yue Liu, Haoran Li, Shih-Chin Cheng

Cell Rep· June 2025

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Dietary succinate supplementation alleviates DSS-induced colitis via the IL-4Rα/Hif-1α Axis.
Laiying Liang, Buyun Dang, Xiaomei Ouyang, Xianling Zhao, Yongdong Huang, Xiaoshen Cheng, Shih-Chin Cheng

Int Immunopharmacol· April 2025

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Human endogenous retrovirus-H long terminal repeat-associating 2: an emerging immune checkpoint for cancer immunotherapy.
Zeya Cao, Youping Wang, Shih-Chin Cheng, Nanhai He

J Leukoc Biol· February 2025

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Persistent bone marrow hemozoin accumulation confers a survival advantage against bacterial infection via cell-intrinsic Myd88 signaling.
Yanhui Zhu, Qingxiang Gao, Jia Zhang, Yu Cheng, Shuzhen Yang, Shih-Chin Cheng

Cell Rep· October 2024

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Lymphatic-localized Treg-mregDC crosstalk limits antigen trafficking and restrains anti-tumor immunity.
Siyuan You, Shuqin Li, Lingsu Zeng, Jinsheng Song, Zifeng Li, Shih-Chin Cheng

Cancer Cell· August 2024

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Glutamate oxaloacetate transaminase 1 is dispensable in macrophage differentiation and anti-pathogen response.
Lishan Zhang, Zhengyi Wu, Xuanhui Qiu, Jia Zhang, Shih-Chin Cheng

Commun Biol· July 2024

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Exploring the limitations of mitochondrial dye as a genuine horizontal mitochondrial transfer surrogate.
Chuanfang Chen, Haige Li, Jia Zhang, Shih-Chin Cheng

Commun Biol· March 2024

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The transcription factor Zeb1 controls homeostasis and function of type 1 conventional dendritic cells.
Yan Wang, Quan Zhang, Tingting He, Yechen Wang, Tianqi Lu, Shih-Chin Cheng

Nat Commun· October 2023

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Intranasal influenza-vectored COVID-19 vaccine restrains the SARS-CoV-2 inflammatory response in hamsters.
Liang Zhang, Yao Jiang, Jinhang He, Junyu Chen, Ruoyao Qi, Shih Chin Cheng, Tong Cheng

Nat Commun· July 2023

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The glycolysis/HIF-1α axis defines the inflammatory role of IL-4-primed macrophages.
Buyun Dang, Qingxiang Gao, Lishan Zhang, Jia Zhang, Hanyi Cai, Stanley Ching-Cheng Huang, Shih-Chin Cheng

Cell Rep· May 2023

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Correction: FOXM1 is required for small cell lung cancer tumorigenesis and associated with poor clinical prognosis.
Sheng-Kai Liang, Chia-Chan Hsu, Hsiang-Lin Song, Yu-Chi Huang, Chun-Wei Kuo, Chien-Cheng Li, Shih-Chin Cheng

Oncogene· December 2021

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FOXM1 is required for small cell lung cancer tumorigenesis and associated with poor clinical prognosis.
Sheng-Kai Liang, Chia-Chan Hsu, Hsiang-Lin Song, Yu-Chi Huang, Chun-Wei Kuo, Chien-Cheng Li, Shih-Chin Cheng

Oncogene· July 2021

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Impact of Intermittent Hypoxia on Sepsis Outcomes in a Murine Model.
Kun-Ta Chou, Shih-Chin Cheng, Shiang-Fen Huang, Diahn-Warng Perng, Shi-Chuan Chang

Sci Rep· September 2019

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High-Mobility Group Nucleosome-Binding Protein 1 as Endogenous Ligand Induces Innate Immune Tolerance in a TLR4-Sirtuin-1 Dependent Manner in Human Blood Peripheral Mononuclear Cells.
Rob J W Arts, Po-Kai Huang, De Yang, Leo A B Joosten, Jos W M van der Meer, Shih-Chin Cheng

Front Immunol· May 2019

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Genomic and Expression Analyses Identify a Disease-Modifying Variant for Fibrostenotic Crohn's Disease.
Marijn C Visschedijk, Lieke M Spekhorst, Shih-Chin Cheng, Ellen S van Loo, B H Dianne Jansen

J Crohns Colitis· April 2018

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Glutaminolysis and Fumarate Accumulation Integrate Immunometabolic and Epigenetic Programs in Trained Immunity.
Rob J W Arts, Boris Novakovic, Rob Ter Horst, Agostinho Carvalho, Siroon Bekkering, Shih-Chin Cheng

Cell Metab· December 2016

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Rewiring cellular metabolism via the AKT/mTOR pathway contributes to host defence against Mycobacterium tuberculosis in human and murine cells.
Ekta Lachmandas, Macarena Beigier-Bompadre, Shih-Chin Cheng, Vinod Kumar, Arjan van Laarhoven

Eur J Immunol· November 2016

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Fungal Chitin Induces Trained Immunity in Human Monocytes during Cross-talk of the Host with Saccharomyces cerevisiae.
Lisa Rizzetto, Daniela C Ifrim, Silvia Moretti, Noemi Tocci, Shih-Chin Cheng

J Biol Chem· April 2016

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Broad defects in the energy metabolism of leukocytes underlie immunoparalysis in sepsis.
Shih-Chin Cheng, Brendon P Scicluna, Rob J W Arts, Mark S Gresnigt, Ekta Lachmandas

Nat Immunol· April 2016

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Borrelia-induced cytokine production is mediated by spleen tyrosine kinase (Syk) but is Dectin-1 and Dectin-2 independent.
Marije Oosting, Kathrin Buffen, Shih-Chin Cheng, Ineke C Verschueren, Frank Koentgen

Cytokine· December 2015

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Ubiquitin Ligase TRIM62 Regulates CARD9-Mediated Anti-fungal Immunity and Intestinal Inflammation.
Zhifang Cao, Kara L Conway, Robert J Heath, Jason S Rush, Elizaveta S Leshchiner, Shih-Chin Cheng

Immunity· October 2015

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The RIG-I-like helicase receptor MDA5 (IFIH1) is involved in the host defense against Candida infections.
Martin Jaeger, Robin van der Lee, Shih-Chin Cheng, Melissa D Johnson, Vinod Kumar

Eur J Clin Microbiol Infect Dis· May 2015

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An anti-inflammatory property of Candida albicans β-glucan: Induction of high levels of interleukin-1 receptor antagonist via a Dectin-1/CR3 independent mechanism.
Sanne P Smeekens, Mark S Gresnigt, Katharina L Becker, Shih-Chin Cheng, Stejara A Netea

Cytokine· February 2015

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Human TLR10 is an anti-inflammatory pattern-recognition receptor.
Marije Oosting, Shih-Chin Cheng, Judith M Bolscher, Rachel Vestering-Stenger, Theo S Plantinga

Proc Natl Acad Sci U S A· October 2014

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