Publications by authors named "Shinichi Imamura"

Claim this Profile
D
Discovery of Rogocekib (CTX-712): A Potent and Selective CLK Inhibitor for Cancer Treatment.
Youichi Kawakita, Takuto Kojima, Noriyuki Nii, Yoshiteru Ito, Nobuki Sakauchi, Keisuke Imamura, Shinichi Imamura

ACS Med Chem Lett· October 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
E
Evaluation of specific binding of [C]TZ7774 to the receptor-interacting protein kinase 1 (RIPK1) in the brain.
Takayuki Sakai, Takashi Yamada, Hiroshi Ikenuma, Aya Ogata, Masanori Ichise, Shinichi Imamura

Am J Nucl Med Mol Imaging· October 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
A novel PET probe to selectively image heat shock protein 90α/β isoforms in the brain.
Takayuki Sakai, Aya Ogata, Hiroshi Ikenuma, Takashi Yamada, Saori Hattori, Shinichi Imamura

EJNMMI Radiopharm Chem· March 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
N
New Series of Potent Allosteric Inhibitors of Deoxyhypusine Synthase.
Yuta Tanaka, Osamu Kurasawa, Akihiro Yokota, Michael G Klein, Bunnai Saito, Shinichi Imamura

ACS Med Chem Lett· August 2020

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Discovery of Novel Allosteric Inhibitors of Deoxyhypusine Synthase.
Yuta Tanaka, Osamu Kurasawa, Akihiro Yokota, Michael G Klein, Koji Ono, Shinichi Imamura

J Med Chem· March 2020

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Discovery of novel serine palmitoyltransferase inhibitors as cancer therapeutic agents.
Takuto Kojima, Yasutomi Asano, Osamu Kurasawa, Yasuhiro Hirata, Naoki Iwamura, Shinichi Imamura

Bioorg Med Chem· May 2018

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
A Novel LSD1 Inhibitor T-3775440 Disrupts GFI1B-Containing Complex Leading to Transdifferentiation and Impaired Growth of AML Cells.
Yoshinori Ishikawa, Kanae Gamo, Masato Yabuki, Shinji Takagi, Kosei Toyoshima, Shinichi Imamura

Mol Cancer Ther· February 2017

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Structure-based design, synthesis, and evaluation of imidazo[1,2-b]pyridazine and imidazo[1,2-a]pyridine derivatives as novel dual c-Met and VEGFR2 kinase inhibitors.
Shigemitsu Matsumoto, Naoki Miyamoto, Takaharu Hirayama, Hideyuki Oki, Kengo Okada, Shinichi Imamura

Bioorg Med Chem· December 2013

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Design, synthesis, and evaluation of novel VEGFR2 kinase inhibitors: discovery of [1,2,4]triazolo[1,5-a]pyridine derivatives with slow dissociation kinetics.
Yuya Oguro, Douglas R Cary, Naoki Miyamoto, Michiko Tawada, Hidehisa Iwata, Shinichi Imamura

Bioorg Med Chem· August 2013

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
N
Noninvasive determination of speech dominance by single magnetic stimulation of the bilateral hand motor cortex.
Hiroshi Tokimura, Shin-Ichi Imamura, Kazunori Arita

Neurol Med Chir (Tokyo)· July 2013

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
A novel inhibitor of c-Met and VEGF receptor tyrosine kinases with a broad spectrum of in vivo antitumor activities.
Yoshiko Awazu, Kazuhide Nakamura, Akio Mizutani, Yuichi Kakoi, Hidehisa Iwata, Shinichi Imamura

Mol Cancer Ther· June 2013

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
Anti-angiogenic and anti-tumor effects of TAK-593, a potent and selective inhibitor of vascular endothelial growth factor and platelet-derived growth factor receptor tyrosine kinase.
Yoshiko Awazu, Akio Mizutani, Yoshinori Nagase, Shuntarou Tsuchiya, Kazuhide Nakamura, Shinichi Imamura

Cancer Sci· April 2013

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Discovery of N-[5-({2-[(cyclopropylcarbonyl)amino]imidazo[1,2-b]pyridazin-6-yl}oxy)-2-methylphenyl]-1,3-dimethyl-1H-pyrazole-5-carboxamide (TAK-593), a highly potent VEGFR2 kinase inhibitor.
Naoki Miyamoto, Nozomu Sakai, Takaharu Hirayama, Kazuhiro Miwa, Yuya Oguro, Shinichi Imamura

Bioorg Med Chem· April 2013

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Design and synthesis of potent inhibitor of apoptosis (IAP) proteins antagonists bearing an octahydropyrrolo[1,2-a]pyrazine scaffold as a novel proline mimetic.
Kentaro Hashimoto, Bunnai Saito, Naoki Miyamoto, Yuya Oguro, Daisuke Tomita, Shinichi Imamura

J Med Chem· February 2013

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Design, synthesis, and evaluation of imidazo[1,2-b]pyridazine derivatives having a benzamide unit as novel VEGFR2 kinase inhibitors.
Naoki Miyamoto, Yuya Oguro, Terufumi Takagi, Hidehisa Iwata, Hiroshi Miki, Shinichi Imamura

Bioorg Med Chem· December 2012

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
A novel pyrrolo[3, 2-d]pyrimidine derivative, as a vascular endothelial growth factor receptor and platelet-derived growth factor receptor tyrosine kinase inhibitor, shows potent antitumor activity by suppression of tumor angiogenesis.
Yoshiko Awazu, Akio Mizutani, Yoshinori Nagase, Hidehisa Iwata, Yuya Oguro, Shinichi Imamura

Cancer Sci· May 2012

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
A Back-to-Front Fragment-Based Drug Design Search Strategy Targeting the DFG-Out Pocket of Protein Tyrosine Kinases.
Hidehisa Iwata, Hideyuki Oki, Kengo Okada, Terufumi Takagi, Michiko Tawada, Shinichi Imamura

ACS Med Chem Lett· April 2012

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
B
Biochemical characterization of a novel type-II VEGFR2 kinase inhibitor: comparison of binding to non-phosphorylated and phosphorylated VEGFR2.
Hidehisa Iwata, Shinichi Imamura, Akira Hori, Mark S Hixon, Hiroyuki Kimura

Bioorg Med Chem· September 2011

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
B
Biochemical characterization of TAK-593, a novel VEGFR/PDGFR inhibitor with a two-step slow binding mechanism.
Hidehisa Iwata, Shinichi Imamura, Akira Hori, Mark S Hixon, Hiroyuki Kimura

Biochemistry· February 2011

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
Chemotherapeutic evaluation of a synthetic tubulysin analogue-dendrimer conjugate in c26 tumor bearing mice.
William C Floyd, Gopal K Datta, Shinichi Imamura, Heidi M Kieler-Ferguson, Katherine Jerger

ChemMedChem· January 2011

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Design, synthesis, and evaluation of 5-methyl-4-phenoxy-5H-pyrrolo[3,2-d]pyrimidine derivatives: novel VEGFR2 kinase inhibitors binding to inactive kinase conformation.
Yuya Oguro, Naoki Miyamoto, Kengo Okada, Terufumi Takagi, Hidehisa Iwata, Shinichi Imamura

Bioorg Med Chem· October 2010

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
N
N-phenyl-N'-[4-(5H-pyrrolo[3,2-d]pyrimidin-4-yloxy)phenyl]ureas as novel inhibitors of VEGFR and FGFR kinases.
Yuya Oguro, Naoki Miyamoto, Terufumi Takagi, Kengo Okada, Yoshiko Awazu, Shinichi Imamura

Bioorg Med Chem· October 2010

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
F
Fragment-based discovery of selective inhibitors of the Mycobacterium tuberculosis protein tyrosine phosphatase PtpA.
Katherine A Rawls, P Therese Lang, Jun Takeuchi, Shinichi Imamura, Tyler D Baguley

Bioorg Med Chem Lett· December 2009

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Differences in two mice strains on kainic acid-induced amygdalar seizures.
Motofumi Kasugai, Koichi Akaike, Shin-ichi Imamura, Hideyuki Matsukubo, Hideshi Tojo

Biochem Biophys Res Commun· June 2007

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Discovery of a piperidine-4-carboxamide CCR5 antagonist (TAK-220) with highly potent Anti-HIV-1 activity.
Shinichi Imamura, Takashi Ichikawa, Youichi Nishikawa, Naoyuki Kanzaki, Katsunori Takashima

J Med Chem· May 2006

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis