Publications by authors named "Shivakumar Keerthikumar"

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Single-cell transcriptomics redefines focal neuroendocrine differentiation as a distinct prostate cancer pathology.
Rosalia Quezada Urban, Shivakumar Keerthikumar, Ashlee Clark, Hong Wang, Belinda Phipson

Mol Oncol· October 2025

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Reprogramming of Androgen Receptor Activity in Castration-resistant Prostate Cancer is Shaped by Truncated Variants.
Mitchell G Lawrence, Shivakumar Keerthikumar, Scott L Townley, Ashlee K Clark, Georgia B Cuffe

Eur Urol Focus· September 2025

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p-AKT Protein Expression Predicts Response to AKT Inhibitor Combined with Docetaxel Therapy in Adenocarcinoma and Neuroendocrine Prostate Cancer.
Hipacia Werneck Gomes, Natalie L Lister, Shivakumar Keerthikumar, Birunthi Niranjan, Michelle G Richards

Clin Cancer Res· July 2025

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Co-targeting BET, CBP, and p300 inhibits neuroendocrine signalling in androgen receptor-null prostate cancer.
Nicholas Choo, Shivakumar Keerthikumar, Susanne Ramm, Daisaku Ashikari, Linda Teng

J Pathol· June 2024

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Multi-substrate Metabolic Tracing Reveals Marked Heterogeneity and Dependency on Fatty Acid Metabolism in Human Prostate Cancer.
Gio Fidelito, David P De Souza, Birunthi Niranjan, William De Nardo, Shivakumar Keerthikumar

Mol Cancer Res· April 2023

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The MURAL collection of prostate cancer patient-derived xenografts enables discovery through preclinical models of uro-oncology.
Gail P Risbridger, Ashlee K Clark, Laura H Porter, Roxanne Toivanen, Andrew Bakshi, Shivakumar Keerthikumar

Nat Commun· August 2021

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Oral administration of bovine milk-derived extracellular vesicles induces senescence in the primary tumor but accelerates cancer metastasis.
Monisha Samuel, Pamali Fonseka, Rahul Sanwlani, Lahiru Gangoda, Sing Ho Chee, Shivakumar Keerthikumar

Nat Commun· June 2021

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Mast Cell-Derived SAMD14 Is a Novel Regulator of the Human Prostate Tumor Microenvironment.
Linda K H Teng, Brooke A Pereira, Shivakumar Keerthikumar, Cheng Huang, Birunthi Niranjan

Cancers (Basel)· March 2021

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Analytical validation of an error-corrected ultra-sensitive ctDNA next-generation sequencing assay.
Heidi Fettke, Jason A Steen, Edmond M Kwan, Patricia Bukczynska, Shivakumar Keerthikumar

Biotechniques· August 2020

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CRISP3 expression drives prostate cancer invasion and progression.
Marianna Volpert, Luc Furic, Jinghua Hu, Anne E O'Connor, Richard J Rebello, Shivakumar Keerthikumar

Endocr Relat Cancer· July 2020

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MTOR signaling orchestrates stress-induced mutagenesis, facilitating adaptive evolution in cancer.
Arcadi Cipponi, David L Goode, Justin Bedo, Mark J McCabe, Marina Pajic, Shivakumar Keerthikumar

Science· June 2020

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Extracellular vesicles secreted by are involved in cell wall remodelling.
Kening Zhao, Mark Bleackley, David Chisanga, Lahiru Gangoda, Pamali Fonseka, Shivakumar Keerthikumar

Commun Biol· April 2020

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Deletion of intestinal Hdac3 remodels the lipidome of enterocytes and protects mice from diet-induced obesity.
Mercedes Dávalos-Salas, Magdalene K Montgomery, Camilla M Reehorst, Rebecca Nightingale, Irvin Ng, Shivakumar Keerthikumar

Nat Commun· November 2019

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Extracellular vesicles containing oncogenic mutant β-catenin activate Wnt signalling pathway in the recipient cells.
Hina Kalra, Lahiru Gangoda, Pamali Fonseka, Sai V Chitti, Michael Liem, Shivakumar Keerthikumar

J Extracell Vesicles· November 2019

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Patient-derived Models of Abiraterone- and Enzalutamide-resistant Prostate Cancer Reveal Sensitivity to Ribosome-directed Therapy.
Mitchell G Lawrence, Daisuke Obinata, Shahneen Sandhu, Luke A Selth, Stephen Q Wong, Shivakumar Keerthikumar

Eur Urol· November 2018

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Arrestin-Domain Containing Protein 1 (Arrdc1) Regulates the Protein Cargo and Release of Extracellular Vesicles.
Sushma Anand, Natalie Foot, Ching-Seng Ang, Kelly M Gembus, Shivakumar Keerthikumar

Proteomics· September 2018

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Label-Based and Label-Free Strategies for Protein Quantitation.
Sushma Anand, Monisha Samuel, Ching-Seng Ang, Shivakumar Keerthikumar, Suresh Mathivanan

Methods Mol Biol· February 2018

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Unassigned MS/MS Spectra: Who Am I?
Mohashin Pathan, Monisha Samuel, Shivakumar Keerthikumar, Suresh Mathivanan

Methods Mol Biol· February 2018

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Proteotypic Peptides and Their Applications.
Shivakumar Keerthikumar, Suresh Mathivanan

Methods Mol Biol· February 2018

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Network Tools for the Analysis of Proteomic Data.
David Chisanga, Shivakumar Keerthikumar, Suresh Mathivanan, Naveen Chilamkurti

Methods Mol Biol· February 2018

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Autotransporter Adhesins in Escherichia coli Pathogenesis.
Julieanne L Vo, Gabriela Constanza Martínez Ortiz, Pramod Subedi, Shivakumar Keerthikumar, Suresh Mathivanan

Proteomics· December 2017

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Proteomic Profiling of Exosomes Secreted by Breast Cancer Cells with Varying Metastatic Potential.
Lahiru Gangoda, Michael Liem, Ching-Seng Ang, Shivakumar Keerthikumar, Christopher G Adda

Proteomics· December 2017

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Bovine milk-derived exosomes from colostrum are enriched with proteins implicated in immune response and growth.
Monisha Samuel, David Chisanga, Michael Liem, Shivakumar Keerthikumar, Sushma Anand

Sci Rep· July 2017

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Powerful differential expression analysis incorporating network topology for next-generation sequencing data.
Malathi S I Dona, Luke A Prendergast, Suresh Mathivanan, Shivakumar Keerthikumar, Agus Salim

Bioinformatics· May 2017

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A novel community driven software for functional enrichment analysis of extracellular vesicles data.
Mohashin Pathan, Shivakumar Keerthikumar, David Chisanga, Riccardo Alessandro, Ching-Seng Ang

J Extracell Vesicles· May 2017

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