Publications by authors named "Sho Akai"

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SAIL66, a next generation CLDN6-targeting T-cell engager, demonstrates potent antitumor efficacy through dual binding to CD3/CD137.
Takayuki Kamikawa, Naoki Kimura, Shinya Ishii, Masaru Muraoka, Tatsushi Kodama, Sho Akai

J Immunother Cancer· October 2024

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Validation of a New Methodology to Create Oral Drugs beyond the Rule of 5 for Intracellular Tough Targets.
Atsushi Ohta, Mikimasa Tanada, Shojiro Shinohara, Yuya Morita, Kazuhiko Nakano, Sho Akai

J Am Chem Soc· November 2023

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Daily ascending dosing in cynomolgus monkeys to mitigate cytokine release syndrome induced by ERY22, surrogate for T-cell redirecting bispecific antibody ERY974 for cancer immunotherapy.
Yoshika Iwata, Masanori Sasaki, Asako Harada, Junko Taketo, Toshiko Hara, Sho Akai

Toxicol Appl Pharmacol· September 2019

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Establishment and characterization of a mouse model of rhabdomyolysis by coadministration of statin and fibrate.
Katsuhito Watanabe, Shingo Oda, Akiko Matsubara, Sho Akai, Tsuyoshi Yokoi

Toxicol Lett· June 2019

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Strain and interindividual differences in lamotrigine-induced liver injury in mice.
Sho Akai, Shingo Oda, Tsuyoshi Yokoi

J Appl Toxicol· March 2019

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Establishment of a drug-induced rhabdomyolysis mouse model by co-administration of ciprofloxacin and atorvastatin.
Akiko Matsubara, Shingo Oda, Sho Akai, Koichi Tsuneyama, Tsuyoshi Yokoi

Toxicol Lett· July 2018

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miRNA in Rat Liver Sinusoidal Endothelial Cells and Hepatocytes and Application to Circulating Biomarkers that Discern Pathogenesis of Liver Injuries.
Shingo Oda, Masaki Takeuchi, Sho Akai, Yuji Shirai, Koichi Tsuneyama

Am J Pathol· April 2018

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Toxicological role of an acyl glucuronide metabolite in diclofenac-induced acute liver injury in mice.
Shingo Oda, Yuji Shirai, Sho Akai, Akira Nakajima, Koichi Tsuneyama

J Appl Toxicol· May 2017

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Establishment of a novel mouse model for pioglitazone-induced skeletal muscle injury.
Sho Akai, Shingo Oda, Tsuyoshi Yokoi

Toxicology· May 2017

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MicroRNA-mediated Th2 bias in methimazole-induced acute liver injury in mice.
Yasuaki Uematsu, Sho Akai, Tomoaki Tochitani, Shingo Oda, Toru Yamada

Toxicol Appl Pharmacol· September 2016

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Zomepirac Acyl Glucuronide Is Responsible for Zomepirac-Induced Acute Kidney Injury in Mice.
Atsushi Iwamura, Katsuhito Watanabe, Sho Akai, Tsubasa Nishinosono, Koichi Tsuneyama

Drug Metab Dispos· July 2016

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Kupffer cell-mediated exacerbation of methimazole-induced acute liver injury in rats.
Sho Akai, Yasuaki Uematsu, Koichi Tsuneyama, Shingo Oda, Tsuyoshi Yokoi

J Appl Toxicol· May 2016

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Cell proliferative activity in the kidney of young growing rat analyzed using flash and cumulative labeling with bromodeoxyuridine.
Masami Suzuki, Kaori Isobe, Etsuko Fujii, Masaki Yamazaki, Yayoi Takai, Sho Akai

J Toxicol Sci· October 2010

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An in vitro drug-induced hepatotoxicity screening system using CYP3A4-expressing and gamma-glutamylcysteine synthetase knockdown cells.
Hiroko Hosomi, Sho Akai, Keiichi Minami, Yukitaka Yoshikawa, Tatsuki Fukami

Toxicol In Vitro· April 2010

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Drug-induced hepatotoxicity test using gamma-glutamylcysteine synthetase knockdown rat.
Mayu Morita, Sho Akai, Hiroko Hosomi, Koichi Tsuneyama, Miki Nakajima

Toxicol Lett· September 2009

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Knock down of gamma-glutamylcysteine synthetase in rat causes acetaminophen-induced hepatotoxicity.
Sho Akai, Hiroko Hosomi, Keiichi Minami, Koichi Tsuneyama, Miki Katoh

J Biol Chem· August 2007

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Self-assembly of natural light-harvesting bacteriochlorophylls of green sulfur photosynthetic bacteria in silicate capsules as stable models of chlorosomes.
Yoshitaka Saga, Sho Akai, Tomohiro Miyatake, Hitoshi Tamiaki

Bioconjug Chem· December 2006

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