Publications by authors named "Si Lin Koo"

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A deep-learning model for quantifying circulating tumour DNA from the density distribution of DNA-fragment lengths.
Guanhua Zhu, Chowdhury Rafeed Rahman, Victor Getty, Denis Odinokov, Probhonjon Baruah, Si-Lin Koo

Nat Biomed Eng· March 2025

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The impact of short-course total neoadjuvant therapy, long-course chemoradiotherapy, and upfront surgery on the technical difficulty of total mesorectal excision: an observational study with an intraoperative perspective.
Cheryl Xi-Zi Chong, Frederick H Koh, Hui-Lin Tan, Sharmini Su Sivarajah, Jia-Lin Ng, Wen-Hsin Koo, Si-Lin Koo

Ann Coloproctol· October 2024

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Bystander CD4 T cells infiltrate human tumors and are phenotypically distinct.
Shamin Li, Summer Zhuang, Antja Heit, Si-Lin Koo, Aaron C Tan

Oncoimmunology· December 2022

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The distinct clinical trajectory, metastatic sites, and immunobiology of microsatellite-instability-high cancers.
Shuting Han, Aik Yong Chok, Daniel Yang Yao Peh, Joshua Zhi-Ming Ho, Emile Kwong Wei Tan, Si-Lin Koo

Front Genet· December 2022

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Single-cell and bulk transcriptome sequencing identifies two epithelial tumor cell states and refines the consensus molecular classification of colorectal cancer.
Ignasius Joanito, Pratyaksha Wirapati, Nancy Zhao, Zahid Nawaz, Grace Yeo, Si-Lin Koo

Nat Genet· July 2022

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Radioembolisation with Y90-resin microspheres followed by nivolumab for advanced hepatocellular carcinoma (CA 209-678): a single arm, single centre, phase 2 trial.
David Tai, Kelvin Loke, Apoorva Gogna, Neslihan Arife Kaya, Sze Huey Tan, Si Lin Koo

Lancet Gastroenterol Hepatol· December 2021

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CD30OX40 Treg is associated with improved overall survival in colorectal cancer.
Jian Hang Lam, Michelle Hong, Si-Lin Koo, Clarinda Wei Ling Chua, Kah Ling Lim

Cancer Immunol Immunother· August 2021

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Tissue-specific cell-free DNA degradation quantifies circulating tumor DNA burden.
Guanhua Zhu, Yu A Guo, Danliang Ho, Polly Poon, Zhong Wee Poh, Si-Lin Koo

Nat Commun· April 2021

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Human Tumor-Infiltrating MAIT Cells Display Hallmarks of Bacterial Antigen Recognition in Colorectal Cancer.
Shamin Li, Yannick Simoni, Etienne Becht, Chiew Yee Loh, Naisi Li, Si-Lin Koo

Cell Rep Med· June 2020

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Replication and Meta-analysis of the Association between BDNF Val66Met Polymorphism and Cognitive Impairment in Patients Receiving Chemotherapy.
Chia Jie Tan, Sheree Wan Ting Lim, Yi Long Toh, Terence Ng, Angie Yeo, Koon Mian Foo, Si-Lin Koo

Mol Neurobiol· July 2019

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Analytical Validation of Multiplex Biomarker Assay to Stratify Colorectal Cancer into Molecular Subtypes.
Chanthirika Ragulan, Katherine Eason, Elisa Fontana, Gift Nyamundanda, Noelia Tarazona, Si-Lin Koo

Sci Rep· May 2019

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Cancer Immunotherapy - The Target is Precisely on The Cancer and Also Not.
Si Lin Koo, Who Whong Wang, Han Chong Toh

Ann Acad Med Singap· September 2018

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Human Innate Lymphoid Cell Subsets Possess Tissue-Type Based Heterogeneity in Phenotype and Frequency.
Yannick Simoni, Michael Fehlings, Henrik N Kløverpris, Naomi McGovern, Si-Lin Koo

Immunity· May 2018

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Bystander CD8 T cells are abundant and phenotypically distinct in human tumour infiltrates.
Yannick Simoni, Etienne Becht, Michael Fehlings, Chiew Yee Loh, Si-Lin Koo

Nature· May 2018

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Association of mitochondrial DNA content in peripheral blood with cancer-related fatigue and chemotherapy-related cognitive impairment in early-stage breast cancer patients: a prospective cohort study.
Jung-Woo Chae, Peh Siang Chua, Terence Ng, Angie Hui Ling Yeo, Maung Shwe, Koon Mian Foo, Si-Lin Koo

Breast Cancer Res Treat· April 2018

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Distinct and heterogeneous trajectories of self-perceived cognitive impairment among Asian breast cancer survivors.
Terence Ng, Sreemanee Raaj Dorajoo, Yin Ting Cheung, Yick Ching Lam, Hui Ling Yeo, Koon Mian Foo, Si-Lin Koo

Psychooncology· April 2018

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Human Innate Lymphoid Cell Subsets Possess Tissue-Type Based Heterogeneity in Phenotype and Frequency.
Yannick Simoni, Michael Fehlings, Henrik N Kløverpris, Naomi McGovern, Si-Lin Koo

Immunity· January 2017

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Individualised multiplexed circulating tumour DNA assays for monitoring of tumour presence in patients after colorectal cancer surgery.
Sarah B Ng, Clarinda Chua, Matthew Ng, Anna Gan, Polly Sy Poon, Si-Lin Koo

Sci Rep· January 2017

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Increased CD4 and CD8-positive T cell infiltrate signifies good prognosis in a subset of triple-negative breast cancer.
Hirofumi Matsumoto, Aye Aye Thike, Huihua Li, Joe Yeong, Si-Lin Koo

Breast Cancer Res Treat· April 2016

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Brain-derived neurotrophic factor genetic polymorphism (rs6265) is protective against chemotherapy-associated cognitive impairment in patients with early-stage breast cancer.
Terence Ng, Shu Mei Teo, Hui Ling Yeo, Maung Shwe, Yan Xiang Gan, Koon Mian Foo, Si-Lin Koo

Neuro Oncol· February 2016

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Assessment of Web-Based Consumer Reviews as a Resource for Drug Performance.
Swarnaseetha Adusumalli, HueyTyng Lee, Qiangze Hoi, Si-Lin Koo, Iain Beehuat Tan

J Med Internet Res· August 2015

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Role of inflammatory infiltrates in triple negative breast cancer.
Hirofumi Matsumoto, Si-lin Koo, Rebecca Dent, Puay Hoon Tan, Jabed Iqbal

J Clin Pathol· July 2015

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Current and emerging surveillance strategies to expand the window of opportunity for curative treatment after surgery in colorectal cancer.
Si Lin Koo, Jin Hang Wen, Axel Hillmer, Peh Yean Cheah, Patrick Tan

Expert Rev Anticancer Ther· April 2013

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