Publications by authors named "Sian Rowsell"

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Discovery of checkpoint kinase inhibitor (S)-5-(3-fluorophenyl)-N-(piperidin-3-yl)-3-ureidothiophene-2-carboxamide (AZD7762) by structure-based design and optimization of thiophenecarboxamide ureas.
Vibha Oza, Susan Ashwell, Lynsie Almeida, Patrick Brassil, Jason Breed, Siân Rowsell

J Med Chem· June 2012

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SAR and inhibitor complex structure determination of a novel class of potent and specific Aurora kinase inhibitors.
Nicola M Heron, Malcolm Anderson, David P Blowers, Jason Breed, Jonathan M Eden, Siân Rowsell

Bioorg Med Chem Lett· March 2006

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Imidazo[1,2-b]pyridazines: a potent and selective class of cyclin-dependent kinase inhibitors.
Kate F Byth, Nicola Cooper, Janet D Culshaw, David W Heaton, Sandra E Oakes, Siân Rowsell

Bioorg Med Chem Lett· May 2004

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Crystal structure of human MMP9 in complex with a reverse hydroxamate inhibitor.
Siân Rowsell, Paul Hawtin, Claire A Minshull, Holly Jepson, Sarah M V Brockbank

J Mol Biol· May 2002

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