Publications by authors named "Signe S Pedersen"

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The Gut Microbial Metabolite Butyrate Alleviates IL-1β-Induced Mitochondrial Dysfunction and Oxidative Stress in Pancreatic Islets.
Signe Schultz Pedersen, Richard Denis Maxime De Mets, Joana Mendes Lopes de Melo, Andrea Irazoki, Patrick E MacDonald

FASEB J· June 2025

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Protection of beta cells against cytokine-induced apoptosis by the gut microbial metabolite butyrate.
Kasper Suhr Jørgensen, Signe Schultz Pedersen, Siv Annegrethe Hjorth, Nils Billestrup, Michala Prause

FEBS J· January 2025

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Butyrate functions as a histone deacetylase inhibitor to protect pancreatic beta cells from IL-1β-induced dysfunction.
Signe Schultz Pedersen, Lars Roed Ingerslev, Mathias Olsen, Michala Prause, Nils Billestrup

FEBS J· February 2024

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Targeted Delivery of Butyrate Improves Glucose Homeostasis, Reduces Hepatic Lipid Accumulation and Inflammation in db/db Mice.
Signe Schultz Pedersen, Michala Prause, Christina Sørensen, Joachim Størling, Thomas Moritz

Int J Mol Sci· February 2023

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Butyrate inhibits IL-1β-induced inflammatory gene expression by suppression of NF-κB activity in pancreatic beta cells.
Signe Schultz Pedersen, Michala Prause, Kristine Williams, Romain Barrès, Nils Billestrup

J Biol Chem· September 2022

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Coding variants identified in patients with diabetes alter PICK1 BAR domain function in insulin granule biogenesis.
Rita C Andersen, Jan H Schmidt, Joscha Rombach, Matthew D Lycas, Nikolaj R Christensen, Signe S Pedersen

J Clin Invest· March 2022

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Partially Hydrolysed Whey Has Superior Allergy Preventive Capacity Compared to Intact Whey Regardless of Amoxicillin Administration in Brown Norway Rats.
Katrine Bækby Graversen, Jeppe Madura Larsen, Signe Schultz Pedersen, Laila Vestergaard Sørensen, Heidi Frahm Christoffersen

Front Immunol· December 2021

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Butyrate Protects Pancreatic Beta Cells from Cytokine-Induced Dysfunction.
Michala Prause, Signe Schultz Pedersen, Violeta Tsonkova, Min Qiao, Nils Billestrup

Int J Mol Sci· September 2021

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Differential bacterial capture and transport preferences facilitate co-growth on dietary xylan in the human gut.
Maria Louise Leth, Morten Ejby, Christopher Workman, David Adrian Ewald, Signe Schultz Pedersen

Nat Microbiol· May 2018

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Comparing different approaches to two-level modelling of electronic health records.
Line Michelsen, Signe S Pedersen, Helene B Tilma, Stig K Andersen

Stud Health Technol Inform· April 2016

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Development of methods for usability evaluations of EHR systems.
Lars H Lilholt, Signe S Pedersen, Inge Madsen, Per H Nielsen, Niels Boye

Stud Health Technol Inform· January 2007

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