Publications by authors named "Silvana Opp"

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Sindbis Virus Platform Provides an Oncolytic-Virus-Mediated and Immunotherapeutic Strategy to Overcome the Challenging Microenvironment of Pancreatic Cancer.
Silvana Opp, Christine Pampeno, Alicia Hurtado, Daniel Meruelo

Pharmaceuticals (Basel)· May 2025

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Sindbis Virus Vaccine Platform: A Promising Oncolytic Virus-Mediated Approach for Ovarian Cancer Treatment.
Christine Pampeno, Silvana Opp, Alicia Hurtado, Daniel Meruelo

Int J Mol Sci· March 2024

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Channeling the Natural Properties of Sindbis Alphavirus for Targeted Tumor Therapy.
Christine Pampeno, Alicia Hurtado, Silvana Opp, Daniel Meruelo

Int J Mol Sci· October 2023

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Potent and Targeted Sindbis Virus Platform for Immunotherapy of Ovarian Cancer.
Silvana Opp, Alicia Hurtado, Christine Pampeno, Ziyan Lin, Daniel Meruelo

Cells· December 2022

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Nuclear restriction of HIV-1 infection by SUN1.
Mirjana Persaud, Anastasia Selyutina, Cindy Buffone, Silvana Opp, Daniel A Donahue

Sci Rep· September 2021

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Combination of a Sindbis-SARS-CoV-2 Spike Vaccine and αOX40 Antibody Elicits Protective Immunity Against SARS-CoV-2 Induced Disease and Potentiates Long-Term SARS-CoV-2-Specific Humoral and T-Cell Immunity.
Antonella Scaglione, Silvana Opp, Alicia Hurtado, Ziyan Lin, Christine Pampeno

Front Immunol· August 2021

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Combination of a Sindbis-SARS-CoV-2 spike vaccine and αOX40 antibody elicits protective immunity against SARS-CoV-2 induced disease and potentiates long-term SARS-CoV-2-specific humoral and T-cell immunity.
Antonella Scaglione, Silvana Opp, Alicia Hurtado, Ziyan Lin, Christine Pampeno

bioRxiv· June 2021

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Sindbis Virus with Anti-OX40 Overcomes the Immunosuppressive Tumor Microenvironment of Low-Immunogenic Tumors.
Iris Scherwitzl, Silvana Opp, Alicia M Hurtado, Christine Pampeno, Cynthia Loomis

Mol Ther Oncolytics· June 2020

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Molecular and metabolic pathways mediating curative treatment of a non-Hodgkin B cell lymphoma by Sindbis viral vectors and anti-4-1BB monoclonal antibody.
Minjun Yu, Iris Scherwitzl, Silvana Opp, Aristotelis Tsirigos, Daniel Meruelo

J Immunother Cancer· July 2019

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The ability of SAMHD1 to block HIV-1 but not SIV requires expression of MxB.
Cindy Buffone, Juliane Kutzner, Silvana Opp, Alicia Martinez-Lopez, Anastasia Selyutina

Virology· May 2019

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Nup153 Unlocks the Nuclear Pore Complex for HIV-1 Nuclear Translocation in Nondividing Cells.
Cindy Buffone, Alicia Martinez-Lopez, Thomas Fricke, Silvana Opp, Marco Severgnini

J Virol· October 2018

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Localization to detergent-resistant membranes and HIV-1 core entry inhibition correlate with HIV-1 restriction by SERINC5.
Bianca Schulte, Anastasia Selyutina, Silvana Opp, Alon Herschhorn, Joseph G Sodroski

Virology· February 2018

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Bicaudal D2 facilitates the cytoplasmic trafficking and nuclear import of HIV-1 genomes during infection.
Adarsh Dharan, Silvana Opp, Omar Abdel-Rahim, Sevnur Komurlu Keceli, Sabrina Imam

Proc Natl Acad Sci U S A· December 2017

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The small-molecule 3G11 inhibits HIV-1 reverse transcription.
Silvana Opp, Thomas Fricke, Caitlin Shepard, Dmytro Kovalskyy, Akash Bhattacharya

Chem Biol Drug Des· April 2017

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Ebselen, a Small-Molecule Capsid Inhibitor of HIV-1 Replication.
Suzie Thenin-Houssier, Ian Mitchelle S de Vera, Laura Pedro-Rosa, Angela Brady, Audrey Richard, Silvana Opp

Antimicrob Agents Chemother· April 2016

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SUN2 Overexpression Deforms Nuclear Shape and Inhibits HIV.
Daniel A Donahue, Sonia Amraoui, Francesca di Nunzio, Camille Kieffer, Françoise Porrot, Silvana Opp

J Virol· April 2016

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HIV-1 capsid is involved in post-nuclear entry steps.
Nan-Yu Chen, Lihong Zhou, Paul J Gane, Silvana Opp, Neil J Ball

Retrovirology· April 2016

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TRIM5α-Mediated Ubiquitin Chain Conjugation Is Required for Inhibition of HIV-1 Reverse Transcription and Capsid Destabilization.
Edward M Campbell, Jared Weingart, Paola Sette, Silvana Opp, Jaya Sastri

J Virol· February 2016

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MxB Is Not Responsible for the Blocking of HIV-1 Infection Observed in Alpha Interferon-Treated Cells.
Silvana Opp, Daniel A S A Vieira, Bianca Schulte, Sumit K Chanda, Felipe Diaz-Griffero

J Virol· December 2015

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Restriction of HIV-1 Requires the N-Terminal Region of MxB as a Capsid-Binding Motif but Not as a Nuclear Localization Signal.
Bianca Schulte, Cindy Buffone, Silvana Opp, Francesca Di Nunzio, Daniel Augusto De Souza Aranha Vieira

J Virol· August 2015

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Multifactorial modulation of susceptibility to l-lysine in an animal model of glutaric aciduria type I.
Sven W Sauer, Silvana Opp, Shoko Komatsuzaki, Anna-Eva Blank, Michel Mittelbronn

Biochim Biophys Acta· May 2015

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Understanding cerebral L-lysine metabolism: the role of L-pipecolate metabolism in Gcdh-deficient mice as a model for glutaric aciduria type I.
Roland Posset, Silvana Opp, Eduard A Struys, Alfred Völkl, Heribert Mohr

J Inherit Metab Dis· March 2015

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Contribution of MxB oligomerization to HIV-1 capsid binding and restriction.
Cindy Buffone, Bianca Schulte, Silvana Opp, Felipe Diaz-Griffero

J Virol· March 2015

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BI-2 destabilizes HIV-1 cores during infection and Prevents Binding of CPSF6 to the HIV-1 Capsid.
Thomas Fricke, Cindy Buffone, Silvana Opp, Jose Valle-Casuso, Felipe Diaz-Griffero

Retrovirology· December 2014

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T cell activation is driven by an ADP-dependent glucokinase linking enhanced glycolysis with mitochondrial reactive oxygen species generation.
Marcin M Kamiński, Sven W Sauer, Marian Kamiński, Silvana Opp, Thorsten Ruppert

Cell Rep· November 2012

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