Publications by authors named "Simon J Davis"

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Solution structure and synaptic analyses reveal determinants of bispecific T cell engager potency.
Alexander Leithner, Oskar Staufer, Tanmay Mitra, Falk Liberta, Salvatore Valvo, Simon J Davis

Proc Natl Acad Sci U S A· June 2025

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The Structural Biology of T-Cell Antigen Detection at Close Contacts.
Yuan Lui, João Ferreira Fernandes, Mai T Vuong, Sumana Sharma, Ana Mafalda Santos, Simon J Davis

Immunol Rev· May 2025

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Permissive central tolerance plus defective peripheral checkpoints license pathogenic memory B cells in CASPR2-antibody encephalitis.
Bo Sun, Dominique Fernandes, John Soltys, Anne-Kathrin Kienzler, Sofija Paneva, Simon J Davis

Sci Adv· April 2025

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From structure prediction to function: defining the domain on the African swine fever virus CD2v protein required for binding to erythrocytes.
Ana Luisa Reis, Anusyah Rathakrishnan, Vlad Petrovan, Muneeb Islam, Lynnette Goatley, Simon J Davis

mBio· February 2025

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Permissive central tolerance plus defective peripheral checkpoints licence pathogenic memory B cells in CASPR2-antibody encephalitis.
Bo Sun, Dominique Fernandes, Anne-Kathrin Kienzler, Sofija Paneva, Ruby Harrison, Simon J Davis

bioRxiv· January 2025

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Structure of a fully assembled γδ T cell antigen receptor.
Benjamin S Gully, João Ferreira Fernandes, Sachith D Gunasinghe, Mai T Vuong, Yuan Lui, Simon J Davis

Nature· October 2024

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POLCAM: instant molecular orientation microscopy for the life sciences.
Ezra Bruggeman, Oumeng Zhang, Lisa-Maria Needham, Markus Körbel, Sam Daly, Simon J Davis

Nat Methods· October 2024

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Single-cell transcriptomic analysis of retinal immune regulation and blood-retinal barrier function during experimental autoimmune uveitis.
Joel Quinn, Ahmed Salman, Christopher Paluch, Matthew Jackson-Wood, Michelle E McClements, Simon J Davis

Sci Rep· August 2024

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Tracking in situ checkpoint inhibitor-bound target T cells in patients with checkpoint-induced colitis.
Tarun Gupta, Agne Antanaviciute, Chloe Hyun-Jung Lee, Rosana Ottakandathil Babu, Anna Aulicino, Simon J Davis

Cancer Cell· May 2024

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The CD6 interactome orchestrates ligand-independent T cell inhibitory signaling.
Rita F Santos, Annika de Sousa Linhares, Peter Steinberger, Simon J Davis, Liliana Oliveira

Cell Commun Signal· May 2024

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A high-throughput two-cell assay for interrogating inhibitory signaling pathways in T cells.
Sumana Sharma, Toby Whitehead, Mateusz Kotowski, Emily Zhi Qing Ng, Joseph Clarke, Simon J Davis

Life Sci Alliance· March 2024

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High-density volumetric super-resolution microscopy.
Sam Daly, João Ferreira Fernandes, Ezra Bruggeman, Anoushka Handa, Ruby Peters, Simon J Davis

Nat Commun· March 2024

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Antibody agonists trigger immune receptor signaling through local exclusion of receptor-type protein tyrosine phosphatases.
Anna H Lippert, Christopher Paluch, Meike Gaglioni, Mai T Vuong, James McColl, Simon J Davis

Immunity· February 2024

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A protective multiple gene-deleted African swine fever virus genotype II, Georgia 2007/1, expressing a modified non-haemadsorbing CD2v protein.
Anusyah Rathakrishnan, Ana L Reis, Vlad Petrovan, Lynnette C Goatley, Katy Moffat, Simon J Davis

Emerg Microbes Infect· December 2023

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The current state and future of T-cell exhaustion research.
Edward Jenkins, Toby Whitehead, Martin Fellermeyer, Simon J Davis, Sumana Sharma

Oxf Open Immunol· July 2023

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Tissue-Resident Memory T Cells in Pancreatic Ductal Adenocarcinoma Coexpress PD-1 and TIGIT and Functional Inhibition Is Reversible by Dual Antibody Blockade.
Hayden Pearce, Wayne Croft, Samantha M Nicol, Sandra Margielewska-Davies, Richard Powell, Simon J Davis

Cancer Immunol Res· April 2023

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Antigen discrimination by T cells relies on size-constrained microvillar contact.
Edward Jenkins, Markus Körbel, Caitlin O'Brien-Ball, James McColl, Kevin Y Chen, Simon J Davis

Nat Commun· March 2023

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Combination CD200R/PD-1 blockade in a humanised mouse model.
Martin Fellermeyer, Consuelo Anzilotti, Christopher Paluch, Richard J Cornall, Simon J Davis

Immunother Adv· March 2023

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The kinase occupancy of T cell coreceptors reconsidered.
Alexander M Mørch, Falk Schneider, Edward Jenkins, Ana Mafalda Santos, Scott E Fraser, Simon J Davis

Proc Natl Acad Sci U S A· December 2022

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resPAINT: Accelerating Volumetric Super-Resolution Localisation Microscopy by Active Control of Probe Emission.
Edward W Sanders, Alexander R Carr, Ezra Bruggeman, Markus Körbel, Sarah I Benaissa, Simon J Davis

Angew Chem Int Ed Engl· October 2022

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resPAINT: Accelerating Volumetric Super-Resolution Localisation Microscopy by Active Control of Probe Emission.
Edward W Sanders, Alexander R Carr, Ezra Bruggeman, Markus Körbel, Sarah I Benaissa, Simon J Davis

Angew Chem Weinheim Bergstr Ger· October 2022

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Differences in CD80 and CD86 transendocytosis reveal CD86 as a key target for CTLA-4 immune regulation.
Alan Kennedy, Erin Waters, Behzad Rowshanravan, Claudia Hinze, Cayman Williams, Simon J Davis

Nat Immunol· September 2022

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Structure of a fully assembled tumor-specific T cell receptor ligated by pMHC.
Lukas Sušac, Mai T Vuong, Christoph Thomas, Sören von Bülow, Caitlin O'Brien-Ball, Simon J Davis

Cell· August 2022

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Single-cell measurements of two-dimensional binding affinity across cell contacts.
Manto Chouliara, Victoria Junghans, Tommy Dam, Ana Mafalda Santos, Simon J Davis

Biophys J· November 2021

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Trapping or slowing the diffusion of T cell receptors at close contacts initiates T cell signaling.
Kevin Y Chen, Edward Jenkins, Markus Körbel, Aleks Ponjavic, Anna H Lippert, Simon J Davis

Proc Natl Acad Sci U S A· September 2021

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