Publications by authors named "Simon Lovestone"

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The evolution of Alzheimer's target identification: Towards a fusion of artificial and cellular intelligence.
Gayle Wittenberg, Fiona Elwood, Andrea Houghton, Tommaso Mansi, Bart Smets, Simon Lovestone

J Prev Alzheimers Dis· December 2025

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Developing Topics.
Pieter J van der Veere, Argonde C van Harten, Ingrid S van Maurik, Charlotte E Teunissen, Frederik Barkhof, Simon Lovestone

Alzheimers Dement· December 2025

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Biomarkers.
Jamie Mitchell, Nowran Nasr, Eimear McLaughlin, Tony Thayanandan, Jennifer Lawson, Simon Lovestone

Alzheimers Dement· December 2025

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Cerebrospinal fluid proteome alterations related to depressive symptoms in cognitive decline and Alzheimer's disease.
Miriam Rabl, Willem L Hartog, Wiesje M van der Flier, Yolande A L Pijnenburg, Charlotte E Teunissen, Simon Lovestone

Alzheimers Dement· December 2025

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Cerebrospinal fluid proteomic associations of APOE genotypes reveal distinct protective and risk mechanisms for Alzheimer's disease.
Eleonora M Vromen, Senne B Lageman, Johan Gobom, Rik van der Kant, Valerija Dobricic, Simon Lovestone

Alzheimers Dement· October 2025

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The association of diabetes with Alzheimer's disease biomarkers and vascular burden across European aging and memory clinic cohorts.
Veerle van Gils, Willemijn J Jansen, Wiesje M van der Flier, Pablo Martinez-Lage, Jakub Hort, Simon Lovestone

Alzheimers Dement· October 2025

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The Global Neurodegeneration Proteomics Consortium: biomarker and drug target discovery for common neurodegenerative diseases and aging.
Farhad Imam, Rowan Saloner, Jacob W Vogel, Varsha Krish, Gamal Abdel-Azim, Simon Lovestone

Nat Med· August 2025

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The GNPC provides a proteomic resource for biomarker discovery and mechanistic insight in neurodegenerative disease.
Simon Lovestone, Farhad Imam,

Nat Aging· July 2025

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Cerebrospinal fluid proteomic profiling of cognitively unimpaired individuals with suspected non-Alzheimer's disease pathophysiology.
Aurore Delvenne, Johan Gobom, Lianne M Reus, Valerija Dobricic, Mara Ten Kate, Simon Lovestone

Brain Commun· June 2025

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Changes in iPSC-astrocyte morphology reflect Alzheimer's disease patient clinical markers.
Helen A Rowland, Georgina Miller, Qiang Liu, Shuhan Li, Nicola R Sharp, Simon Lovestone

Stem Cells· March 2025

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Synaptic protein CSF levels relate to memory scores in individuals without dementia.
Kirsten E J Wesenhagen, Diederick M de Leeuw, Jori Tomassen, Johan Gobom, Isabelle Bos, Simon Lovestone

Alzheimers Res Ther· March 2025

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Blood DNA methylomic signatures associated with CSF biomarkers of Alzheimer's disease in the EMIF-AD study.
Rebecca G Smith, Ehsan Pishva, Morteza Kouhsar, Jennifer Imm, Valerija Dobricic, Simon Lovestone

Alzheimers Dement· October 2024

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Blood-based multivariate methylation risk score for cognitive impairment and dementia.
Jarno Koetsier, Rachel Cavill, Rick Reijnders, Joshua Harvey, Jan Homann, Simon Lovestone

Alzheimers Dement· October 2024

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CSF proteomic profiles of neurodegeneration biomarkers in Alzheimer's disease.
Aurore Delvenne, Johan Gobom, Suzanne E Schindler, Mara Ten Kate, Lianne M Reus, Simon Lovestone

Alzheimers Dement· September 2024

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Involvement of the choroid plexus in Alzheimer's disease pathophysiology: findings from mouse and human proteomic studies.
Aurore Delvenne, Charysse Vandendriessche, Johan Gobom, Marlies Burgelman, Pieter Dujardin, Simon Lovestone

Fluids Barriers CNS· July 2024

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Synaptic protein CSF levels relate to memory scores in individuals without dementia.
Kirsten E J Wesenhagen, Diederick M de Leeuw, Jori Tomassen, Johan Gobom, Isabelle Bos, Simon Lovestone

Res Sq· July 2024

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Paired plasma lipidomics and proteomics analysis in the conversion from mild cognitive impairment to Alzheimer's disease.
Alicia Gómez-Pascual, Talel Naccache, Jin Xu, Kourosh Hooshmand, Asger Wretlind, Simon Lovestone

Comput Biol Med· June 2024

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Characterization of APOE Christchurch carriers in 455,306 UK Biobank participants.
Karen Y He, Ekaterina A Khramtsova, Alfredo Cabrera-Socorro, Yanfei Zhang, Shuwei Li, Simon Lovestone

Mol Neurodegener· November 2023

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Multivariate GWAS of Alzheimer's disease CSF biomarker profiles implies GRIN2D in synaptic functioning.
Alexander Neumann, Olena Ohlei, Fahri Küçükali, Isabelle J Bos, Jigyasha Timsina, Simon Lovestone

Genome Med· October 2023

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Multiomics profiling of human plasma and cerebrospinal fluid reveals ATN-derived networks and highlights causal links in Alzheimer's disease.
Liu Shi, Jin Xu, Rebecca Green, Asger Wretlind, Jan Homann, Simon Lovestone

Alzheimers Dement· August 2023

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Whole-exome rare-variant analysis of Alzheimer's disease and related biomarker traits.
Fahri Küçükali, Alexander Neumann, Jasper Van Dongen, Tim De Pooter, Geert Joris, Simon Lovestone

Alzheimers Dement· June 2023

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Predicting progression to Alzheimer's disease with human hippocampal progenitors exposed to serum.
Aleksandra Maruszak, Edina Silajdžić, Hyunah Lee, Tytus Murphy, Benjamine Liu, Simon Lovestone

Brain· May 2023

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Pharmacological modulation of TSPO in microglia/macrophages and neurons in a chronic neurodegenerative model of prion disease.
Marta Vicente-Rodríguez, Renzo Mancuso, Alba Peris-Yague, Camilla Simmons, , Simon Lovestone

J Neuroinflammation· April 2023

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Identification of a possible proteomic biomarker in Parkinson's disease: discovery and replication in blood, brain and cerebrospinal fluid.
Laura Winchester, Imelda Barber, Michael Lawton, Jessica Ash, Benjamine Liu, Simon Lovestone

Brain Commun· December 2022

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Predicting AT(N) pathologies in Alzheimer's disease from blood-based proteomic data using neural networks.
Yuting Zhang, Upamanyu Ghose, Noel J Buckley, Sebastiaan Engelborghs, Kristel Sleegers, Simon Lovestone

Front Aging Neurosci· November 2022

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