Publications by authors named "Simon Thom"

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Tissue Doppler echocardiography predicts long-term cardiovascular mortality: the Anglo-Scandinavian Cardiac Outcomes Trial (ASCOT) legacy 20-year follow-up study.
Anenta Ratneswaren, Tong Wu, Amit Kaura, Devan Wasan, Somayeh Rostamian, Simon Thom

Open Heart· February 2025

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Evaluation of a portable retinal imaging device: towards a comparative quantitative analysis for morphological measurements of retinal blood vessels.
M Elena Martinez-Perez, Alun D Hughes, Simon A McG Thom, Kim H Parker, Nicholas W Witt

R Soc Open Sci· June 2023

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Cardiopulmonary exercise testing and efficacy of percutaneous coronary intervention: a substudy of the ORBITA trial.
Sashiananthan Ganesananthan, Christopher A Rajkumar, Michael Foley, David Thompson, Alexandra N Nowbar, Simon A Thom

Eur Heart J· September 2022

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Association of Low-Dose Triple Combination Therapy vs Usual Care With Time at Target Blood Pressure: A Secondary Analysis of the TRIUMPH Randomized Clinical Trial.
Sonali R Gnanenthiran, Nelson Wang, Gian Luca Di Tanna, Abdul Salam, Ruth Webster, Simon Thom

JAMA Cardiol· June 2022

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Multiphysics Modelling and Simulation of Thrombolysis via Activated Platelet-Targeted Nanomedicine.
Boram Gu, Yu Huang, Emily Louise Manchester, Alun D Hughes, Simon A McG Thom

Pharm Res· January 2022

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Fibrinogen-mimicking, multiarm nanovesicles for human thrombus-specific delivery of tissue plasminogen activator and targeted thrombolytic therapy.
Yu Huang, Boram Gu, Isabelle I Salles-Crawley, Kirk A Taylor, Li Yu, Simon A Thom

Sci Adv· June 2021

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Achieving optimal adherence to medical therapy by telehealth: Findings from the ORBITA medication adherence sub-study.
David Thompson, Rasha Al-Lamee, Michael Foley, Hakim M Dehbi, Simon Thom

Pharmacol Res Perspect· February 2021

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Association of Low-Dose Triple Combination Therapy With Therapeutic Inertia and Prescribing Patterns in Patients With Hypertension: A Secondary Analysis of the TRIUMPH Trial.
Nelson Wang, Abdul Salam, Ruth Webster, Asita de Silva, Rama Guggilla, Simon Thom

JAMA Cardiol· November 2020

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Omega-3 index and blood pressure responses to eating foods naturally enriched with omega-3 polyunsaturated fatty acids: a randomized controlled trial.
Alice V Stanton, Kirstyn James, Margaret M Brennan, Fiona O'Donovan, Fahad Buskandar, Simon A M Thom

Sci Rep· September 2020

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Dobutamine Stress Echocardiography Ischemia as a Predictor of the Placebo-Controlled Efficacy of Percutaneous Coronary Intervention in Stable Coronary Artery Disease: The Stress Echocardiography-Stratified Analysis of ORBITA.
Rasha K Al-Lamee, Matthew J Shun-Shin, James P Howard, Alexandra N Nowbar, Christopher Rajkumar, David Thompson, Thomas Keeble, Simon Thom

Circulation· December 2019

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Computational simulations of thrombolysis in acute stroke: Effect of clot size and location on recanalisation.
Boram Gu, Andris Piebalgs, Yu Huang, Dylan Roi, Kyriakos Lobotesis, Simon A Thom

Med Eng Phys· November 2019

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Identification of Distinct Arterial Waveform Clusters and a Longitudinal Evaluation of Their Clinical Usefulness.
John D Sluyter, Alun D Hughes, Carlos A Camargo, Simon A McG Thom, Kim H Parker

Hypertension· October 2019

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Fixed-combination, low-dose, triple-pill antihypertensive medication versus usual care in patients with mild-to-moderate hypertension in Sri Lanka: a within-trial and modelled economic evaluation of the TRIUMPH trial.
Thomas Lung, Stephen Jan, H Asita de Silva, Rama Guggilla, Pallab K Maulik, Simon Thom

Lancet Glob Health· October 2019

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Automatic optic disc detection in colour fundus images by means of multispectral analysis and information content.
M Elena Martinez-Perez, Nicholas Witt, Kim H Parker, Alun D Hughes, Simon A M Thom

PeerJ· June 2019

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An activated-platelet-sensitive nanocarrier enables targeted delivery of tissue plasminogen activator for effective thrombolytic therapy.
Yu Huang, Li Yu, Jie Ren, Boram Gu, Colin Longstaff, Simon A Thom

J Control Release· April 2019

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Mathematical Modelling of Intravenous Thrombolysis in Acute Ischaemic stroke: Effects of Dose Regimens on Levels of Fibrinolytic Proteins and Clot Lysis Time.
Boram Gu, Andris Piebalgs, Yu Huang, Colin Longstaff, Alun D Hughes, Simon A Thom

Pharmaceutics· March 2019

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Reaching cardiovascular prevention guideline targets with a polypill-based approach: a meta-analysis of randomised clinical trials.
Vanessa Selak, Ruth Webster, Sandrine Stepien, Chris Bullen, Anushka Patel, Simon Thom

Heart· January 2019

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Publisher Correction: Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits.
Evangelos Evangelou, Helen R Warren, David Mosen-Ansorena, Borbala Mifsud, Raha Pazoki, Simon Thom

Nat Genet· December 2018

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Fractional Flow Reserve and Instantaneous Wave-Free Ratio as Predictors of the Placebo-Controlled Response to Percutaneous Coronary Intervention in Stable Single-Vessel Coronary Artery Disease.
Rasha Al-Lamee, James P Howard, Matthew J Shun-Shin, David Thompson, Hakim-Moulay Dehbi, Thomas Keeble, Simon A Thom

Circulation· October 2018

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Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits.
Evangelos Evangelou, Helen R Warren, David Mosen-Ansorena, Borbala Mifsud, Raha Pazoki, Simon Thom

Nat Genet· October 2018

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Randomized Crossover Trial of the Impact of Morning or Evening Dosing of Antihypertensive Agents on 24-Hour Ambulatory Blood Pressure.
Neil R Poulter, Christos Savopoulos, Aisha Anjum, Martha Apostolopoulou, Neil Chapman, Simon Thom, David Thompson

Hypertension· October 2018

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Computational Simulations of Thrombolytic Therapy in Acute Ischaemic Stroke.
Andris Piebalgs, Boram Gu, Dylan Roi, Kyriakos Lobotesis, Simon Thom

Sci Rep· October 2018

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Fixed Low-Dose Triple Combination Antihypertensive Medication vs Usual Care for Blood Pressure Control in Patients With Mild to Moderate Hypertension in Sri Lanka: A Randomized Clinical Trial.
Ruth Webster, Abdul Salam, H Asita de Silva, Vanessa Selak, Sandrine Stepien, Simon Thom

JAMA· August 2018

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