Publications by authors named "Simona Ponzi"

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Direct-to-biology platform: From synthesis to biological evaluation of SHP2 allosteric inhibitors.
Simona Ponzi, Federica Ferrigno, Monica Bisbocci, Cristina Alli, Jesus M Ontoria

Bioorg Med Chem Lett· March 2024

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Discovery of a Novel Series of Imidazopyrazine Derivatives as Potent SHP2 Allosteric Inhibitors.
Esther Torrente, Valentina Fodale, Alina Ciammaichella, Federica Ferrigno, Jesus M Ontoria, Simona Ponzi

ACS Med Chem Lett· February 2023

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SAR evolution towards potent C-terminal carboxamide peptide inhibitors of Zika virus NS2B-NS3 protease.
Stefania Colarusso, Federica Ferrigno, Simona Ponzi, Francesca Pavone, Immacolata Conte

Bioorg Med Chem· March 2022

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Optimization of 2-(1H-imidazo-2-yl)piperazines series of Trypanosoma brucei growth inhibitors as potential treatment for the second stage of HAT.
Alina Ciammaichella, Federica Ferrigno, Andreina Basta, Melania D'Amico, Ilaria Biancofiore, Simona Ponzi

Bioorg Med Chem Lett· June 2020

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Discovery of 4-((1-(1H-imidazol-2-yl)alkoxy)methyl)pyridines as a new class of Trypanosoma cruzi growth inhibitors.
Simona Ponzi, Alberto Bresciani, Marcel Kaiser, Valentina Nardi, Emanuela Nizi

Bioorg Med Chem Lett· April 2020

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Improved Selective Class I HDAC and Novel Selective HDAC3 Inhibitors: Beyond Hydroxamic Acids and Benzamides.
Alberto Bresciani, Jesus M Ontoria, Ilaria Biancofiore, Antonella Cellucci, Alina Ciammaichella, Simona Ponzi

ACS Med Chem Lett· April 2019

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Discovery of 2-(1H-imidazo-2-yl)piperazines as a new class of potent and non-cytotoxic inhibitors of Trypanosoma brucei growth in vitro.
Federica Ferrigno, Ilaria Biancofiore, Savina Malancona, Simona Ponzi, Giacomo Paonessa

Bioorg Med Chem Lett· December 2018

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Discovery of a Selective Series of Inhibitors of Plasmodium falciparum HDACs.
Jesus M Ontoria, Giacomo Paonessa, Simona Ponzi, Federica Ferrigno, Emanuela Nizi

ACS Med Chem Lett· May 2016

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Optimization of thienopyrrole-based finger-loop inhibitors of the hepatitis C virus NS5B polymerase.
Jose Ignacio Martin Hernando, Jesus Maria Ontoria, Savina Malancona, Barbara Attenni, Fabrizio Fiore, Simona Ponzi

ChemMedChem· October 2009

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Identification of thieno[3,2-b]pyrroles as allosteric inhibitors of hepatitis C virus NS5B polymerase.
Jesus M Ontoria, Jose I Martìn Hernando, Savina Malancona, Barbara Attenni, Ian Stansfield, Simona Ponzi

Bioorg Med Chem Lett· August 2006

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Active site inhibitors of HCV NS5B polymerase. The development and pharmacophore of 2-thienyl-5,6-dihydroxypyrimidine-4-carboxylic acid.
Ian Stansfield, Salvatore Avolio, Stefania Colarusso, Nadia Gennari, Frank Narjes, Simona Ponzi

Bioorg Med Chem Lett· October 2004

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Capped dipeptide alpha-ketoacid inhibitors of the HCV NS3 protease.
Emanuela Nizi, Uwe Koch, Simona Ponzi, Victor G Matassa, Cristina Gardelli

Bioorg Med Chem Lett· November 2002

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