Publications by authors named "Simone Boehrer"

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Erratum to: Flt3 receptor inhibition reduces constitutive NFκB activation in high-risk myelodysplastic syndrome and acute myeloid leukemia.
Jennifer Grosjean-Raillard, Lionel Adès, Simone Boehrer, Maximilien Tailler, Claire Fabre

Apoptosis· December 2015

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A phase I/II trial of Erlotinib in higher risk myelodysplastic syndromes and acute myeloid leukemia after azacitidine failure.
Sylvain Thepot, Simone Boehrer, Valérie Seegers, Thomas Prebet, Odile Beyne-Rauzy

Leuk Res· December 2014

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Tyrosine kinase inhibitors for the treatment of acute myeloid leukemia: delineation of anti-leukemic mechanisms of action.
Elodie Lainey, Sylvain Thépot, Cyrielle Bouteloup, Marie Sébert, Lionel Adès, Simone Boehrer

Biochem Pharmacol· November 2011

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Coordinated epigenetic regulation of autophagy and apoptosis.
Simone Boehrer, Elodie Lainey, Guido Kroemer

Cell Cycle· September 2011

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Erlotinib antagonizes constitutive activation of SRC family kinases and mTOR in acute myeloid leukemia.
Simone Boehrer, Lorenzo Galluzzi, Elodie Lainey, Cyrielle Bouteloup, Maximilien Tailler

Cell Cycle· September 2011

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Cytotoxic effects of the trifunctional bispecific antibody FBTA05 in ex-vivo cells of chronic lymphocytic leukaemia depend on immune-mediated mechanism.
Simone Boehrer, Petra Schroeder, Tina Mueller, Judith Atz, Kai Uwe Chow

Anticancer Drugs· July 2011

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Hypomethylating agents reactivate FOXO3A in acute myeloid leukemia.
Sylvain Thépot, Elodie Lainey, Thomas Cluzeau, Marie Sébert, Carole Leroy, Simone Boehrer

Cell Cycle· July 2011

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Prognostic factors for response and overall survival in 282 patients with higher-risk myelodysplastic syndromes treated with azacitidine.
Raphael Itzykson, Sylvain Thépot, Bruno Quesnel, Francois Dreyfus, Odile Beyne-Rauzy, Simone Boehrer

Blood· January 2011

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Efficacy and safety of lenalidomide in intermediate-2 or high-risk myelodysplastic syndromes with 5q deletion: results of a phase 2 study.
Lionel Adès, Simone Boehrer, Thomas Prebet, Odile Beyne-Rauzy, Laurence Legros

Blood· April 2009

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Erlotinib and gefitinib for the treatment of myelodysplastic syndrome and acute myeloid leukemia: a preclinical comparison.
Simone Boehrer, Lionel Adès, Lorenzo Galluzzi, Nicolas Tajeddine, Maximilien Tailler

Biochem Pharmacol· December 2008

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Flt3 receptor inhibition reduces constitutive NFkappaB activation in high-risk myelodysplastic syndrome and acute myeloid leukemia.
Jennifer Grosjean-Raillard, Lionel Adès, Simone Boehrer, Maximilien Tailler, Claire Fabre

Apoptosis· September 2008

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A novel effect of DNA methyltransferase and histone deacetylase inhibitors: NFkappaB inhibition in malignant myeloblasts.
Claire Fabre, Jennifer Grosjean, Maximilien Tailler, Simone Boehrer, Lionel Adès

Cell Cycle· July 2008

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Erlotinib exhibits antineoplastic off-target effects in AML and MDS: a preclinical study.
Simone Boehrer, Lionel Adès, Thorsten Braun, Lorenzo Galluzzi, Jennifer Grosjean

Blood· February 2008

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Nonapoptotic role for Apaf-1 in the DNA damage checkpoint.
Yael Zermati, Shahul Mouhamad, Lilli Stergiou, Benjamin Besse, Lorenzo Galluzzi, Simone Boehrer

Mol Cell· November 2007

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Src kinase inhibitors induce apoptosis and mediate cell cycle arrest in lymphoma cells.
Daniel Nowak, Simone Boehrer, Simone Hochmuth, Bettina Trepohl, Wencke Hofmann

Anticancer Drugs· October 2007

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The tyrosine kinase inhibitor AMN107 (Nilotinib) exhibits off-target effects in lymphoblastic cell lines.
Kai Uwe Chow, Daniel Nowak, Bettina Trepohl, Simone Hochmuth, Bernd Schneider, Simone Boehrer

Leuk Lymphoma· July 2007

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Differentiating megakaryocytes in myelodysplastic syndromes succumb to mitochondrial derangement without caspase activation.
Thorsten Braun, Gabrielle Carvalho, Jennifer Grosjean, Lionel Ades, Claire Fabre, Simone Boehrer

Apoptosis· June 2007

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The molecular biology of TRAIL-mediated signaling and its potential therapeutic exploitation in hematopoietic malignancies.
Simone Boehrer, Daniel Nowak, Dieter Hoelzer, Paris S Mitrou, Kai Uwe Chow

Curr Med Chem· September 2006

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Prostate-apoptosis-response-gene-4 increases sensitivity to TRAIL-induced apoptosis.
Simone Boehrer, Daniel Nowak, Elena Puccetti, Martin Ruthardt, Nicole Sattler

Leuk Res· May 2006

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Novel agents aiming at specific molecular targets increase chemosensitivity and overcome chemoresistance in hematopoietic malignancies.
Simone Boehrer, Daniel Nowak, Dieter Hoelzer, Paris S Mitrou, Kai Uwe Chow

Curr Pharm Des· February 2006

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In vivo drug-response in patients with leukemic non-Hodgkin's lymphomas is associated with in vitro chemosensitivity and gene expression profiling.
Kai Uwe Chow, Daniel Nowak, Soo-Zin Kim, Bernd Schneider, Martina Komor, Simone Boehrer

Pharmacol Res· January 2006

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High-dose melphalan is an effective salvage therapy in acute myeloid leukaemia patients with refractory relapse and relapse after autologous stem cell transplantation.
Gesine Bug, Johannes Atta, Stefan A Klein, Bernd Hertenstein, Lothar Bergmann, Simone Boehrer

Ann Hematol· October 2005

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The integrity of the charged pocket in the BTB/POZ domain is essential for the phenotype induced by the leukemia-associated t(11;17) fusion protein PLZF/RARalpha.
Elena Puccetti, Xiaomin Zheng, Daria Brambilla, Anita Seshire, Tim Beissert, Simone Boehrer

Cancer Res· July 2005

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Upon drug-induced apoptosis expression of prostate-apoptosis-response-gene-4 promotes cleavage of caspase-8, bid and mitochondrial release of cytochrome c.
Simone Boehrer, Natasa Kukoc-Zivojnov, Daniel Nowak, Marion Bergmann, Christine Baum

Hematology· April 2005

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Valproic acid stimulates proliferation and self-renewal of hematopoietic stem cells.
Gesine Bug, Hilal Gül, Kerstin Schwarz, Heike Pfeifer, Manuela Kampfmann, Simone Boehrer

Cancer Res· April 2005

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