Publications by authors named "Simone Florian"

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A facile, semi-automatic protocol for the design and production of 3D printed, anatomical customized orthopedic casts for forearm fractures.
Davide Ranaldo, Filippo Zonta, Simone Florian, Jacopo Lazzaro

J Clin Orthop Trauma· July 2023

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Feeding Brassica vegetables to rats leads to the formation of characteristic DNA adducts (from 1-methoxy-3-indolylmethyl glucosinolate) in many tissues.
Hansruedi Glatt, Wolfram Engst, Simone Florian, Monika Schreiner, Chimgee Baasanjav-Gerber

Arch Toxicol· March 2022

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1-Methoxy-3-indolylmethyl DNA adducts in six tissues, and blood protein adducts, in mice under pak choi diet: time course and persistence.
Melanie Wiesner-Reinhold, Gitte Barknowitz, Simone Florian, Inga Mewis, Fabian Schumacher

Arch Toxicol· June 2019

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Impact of genetic modulation of SULT1A enzymes on DNA adduct formation by aristolochic acids and 3-nitrobenzanthrone.
Volker M Arlt, Walter Meinl, Simone Florian, Eszter Nagy, Frantisek Barta

Arch Toxicol· April 2017

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The glucosinolate metabolite 1-methoxy-3-indolylmethyl alcohol induces a gene expression profile in mouse liver similar to the expression signature caused by known genotoxic hepatocarcinogens.
Anke Ehlers, Simone Florian, Fabian Schumacher, Walter Meinl, Dido Lenze

Mol Nutr Food Res· April 2015

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Glucosinolates from pak choi and broccoli induce enzymes and inhibit inflammation and colon cancer differently.
Doris Lippmann, Carsten Lehmann, Simone Florian, Gitte Barknowitz, Michael Haack

Food Funct· June 2014

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Determination of sulfotransferase forms involved in the metabolic activation of the genotoxicant 1-hydroxymethylpyrene using bacterially expressed enzymes and genetically modified mouse models.
Carolin Bendadani, Walter Meinl, Bernhard Monien, Gisela Dobbernack, Simone Florian

Chem Res Toxicol· June 2014

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Deletion of glutathione peroxidase-2 inhibits azoxymethane-induced colon cancer development.
Mike F Müller, Simone Florian, Stefanie Pommer, Martin Osterhoff, R Steven Esworthy

PLoS One· April 2014

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Formation of hepatic DNA adducts by methyleugenol in mouse models: drastic decrease by Sult1a1 knockout and strong increase by transgenic human SULT1A1/2.
Kristin Herrmann, Wolfram Engst, Walter Meinl, Simone Florian, Alexander T Cartus

Carcinogenesis· April 2014

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A secondary metabolite of Brassicales, 1-methoxy-3-indolylmethyl glucosinolate, as well as its degradation product, 1-methoxy-3-indolylmethyl alcohol, forms DNA adducts in the mouse, but in varying tissues and cells.
Fabian Schumacher, Simone Florian, Anke Schnapper, Bernhard H Monien, Inga Mewis

Arch Toxicol· March 2014

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Identification and quantification of protein adducts formed by metabolites of 1-methoxy-3-indolylmethyl glucosinolate in vitro and in mouse models.
Gitte Barknowitz, Wolfram Engst, Stephan Schmidt, Mareike Bernau, Bernhard H Monien, Simone Florian

Chem Res Toxicol· February 2014

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Optimized enzymatic hydrolysis of DNA for LC-MS/MS analyses of adducts of 1-methoxy-3-indolylmethyl glucosinolate and methyleugenol.
Fabian Schumacher, Kristin Herrmann, Simone Florian, Wolfram Engst, Hansruedi Glatt

Anal Biochem· March 2013

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Detection of DNA adducts originating from 1-methoxy-3-indolylmethyl glucosinolate using isotope-dilution UPLC-ESI-MS/MS.
Fabian Schumacher, Wolfram Engst, Bernhard H Monien, Simone Florian, Anke Schnapper

Anal Chem· July 2012

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Toxicity studies with 5-hydroxymethylfurfural and its metabolite 5-sulphooxymethylfurfural in wild-type mice and transgenic mice expressing human sulphotransferases 1A1 and 1A2.
Morana Bauer-Marinovic, Felicitas Taugner, Simone Florian, Hansruedi Glatt

Arch Toxicol· May 2012

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Study of 5-hydroxymethylfurfural and its metabolite 5-sulfooxymethylfurfural on induction of colonic aberrant crypt foci in wild-type mice and transgenic mice expressing human sulfotransferases 1A1 and 1A2.
Simone Florian, Morana Bauer-Marinovic, Felicitas Taugner, Gisela Dobbernack, Bernhard H Monien

Mol Nutr Food Res· April 2012

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Glutathione peroxidase-2 and selenium decreased inflammation and tumors in a mouse model of inflammation-associated carcinogenesis whereas sulforaphane effects differed with selenium supply.
Susanne Krehl, Maria Loewinger, Simone Florian, Anna P Kipp, Antje Banning

Carcinogenesis· March 2012

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Specific alterations of carbohydrate metabolism are associated with hepatocarcinogenesis in mitochondrially impaired mice.
René Thierbach, Simone Florian, Katharina Wolfrum, Anja Voigt, Gunnar Drewes

Hum Mol Genet· February 2012

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Altered tissue distribution of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine-DNA adducts in mice transgenic for human sulfotransferases 1A1 and 1A2.
Gisela Dobbernack, Walter Meinl, Nicole Schade, Simone Florian, Korinna Wend

Carcinogenesis· November 2011

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Metabolic activation of furfuryl alcohol: formation of 2-methylfuranyl DNA adducts in Salmonella typhimurium strains expressing human sulfotransferase 1A1 and in FVB/N mice.
Bernhard H Monien, Kristin Herrmann, Simone Florian, Hansruedi Glatt

Carcinogenesis· October 2011

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Loss of GPx2 increases apoptosis, mitosis, and GPx1 expression in the intestine of mice.
Simone Florian, Susanne Krehl, Maria Loewinger, Anna Kipp, Antje Banning

Free Radic Biol Med· December 2010

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Telomerase deficiency impairs glucose metabolism and insulin secretion.
Doreen Kuhlow, Simone Florian, Guido von Figura, Sandra Weimer, Nadja Schulz

Aging (Albany NY)· October 2010

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Glutathione Peroxidase 2 Inhibits Cyclooxygenase-2-Mediated Migration and Invasion of HT-29 Adenocarcinoma Cells but Supports Their Growth as Tumors in Nude Mice.
Antje Banning, Anna Kipp, Stephanie Schmitmeier, Maria Löwinger, Simone Florian

Cancer Res· December 2008

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ADP-ribosylation factor-like GTPase ARFRP1 is required for trans-Golgi to plasma membrane trafficking of E-cadherin.
Claudia Zahn, Alexander Jaschke, Jörg Weiske, Angela Hommel, Deike Hesse, Simone Florian

J Biol Chem· October 2008

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GPx2 counteracts PGE2 production by dampening COX-2 and mPGES-1 expression in human colon cancer cells.
Antje Banning, Simone Florian, Stefanie Deubel, Sophie Thalmann, Katrin Müller-Schmehl

Antioxid Redox Signal· September 2008

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Pectin does not inhibit intestinal carcinogenesis in APC-deficient Min/+ mice.
Gisela Jacobasch, Gerhard Dongowski, Simone Florian, Katrin Müller-Schmehl, Barbara Raab

J Agric Food Chem· February 2008

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