Publications by authors named "Wolfram Engst"

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Formation of DNA Adducts by 1-Methoxy-3-indolylmethylalcohol, a Breakdown Product of a Glucosinolate, in the Mouse: Impact of the SULT1A1 Status-Wild-Type, Knockout or Humanised.
Hansruedi Glatt, Sarah Yasmin Weißenberg, Anke Ehlers, Alfonso Lampen, Albrecht Seidel, Wolfram Engst

Int J Mol Sci· March 2024

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Feeding Brassica vegetables to rats leads to the formation of characteristic DNA adducts (from 1-methoxy-3-indolylmethyl glucosinolate) in many tissues.
Hansruedi Glatt, Wolfram Engst, Simone Florian, Monika Schreiner, Chimgee Baasanjav-Gerber

Arch Toxicol· March 2022

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Methyleugenol DNA adducts in human liver are associated with SULT1A1 copy number variations and expression levels.
Roman Tremmel, Kristin Herrmann, Wolfram Engst, Walter Meinl, Kathrin Klein

Arch Toxicol· October 2017

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Chalcone Isomerase from Eubacterium ramulus Catalyzes the Ring Contraction of Flavanonols.
Annett Braune, Wolfram Engst, Paul W Elsinghorst, Norbert Furtmann, Jürgen Bajorath

J Bacteriol· November 2016

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Identification and functional expression of genes encoding flavonoid O- and C-glycosidases in intestinal bacteria.
Annett Braune, Wolfram Engst, Michael Blaut

Environ Microbiol· July 2016

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Mild gut inflammation modulates the proteome of intestinal Escherichia coli.
Sara Schumann, Carl Alpert, Wolfram Engst, Robert Klopfleisch, Gunnar Loh

Environ Microbiol· September 2014

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Determination of sulfotransferase forms involved in the metabolic activation of the genotoxicant 1-hydroxymethylpyrene using bacterially expressed enzymes and genetically modified mouse models.
Carolin Bendadani, Walter Meinl, Bernhard Monien, Gisela Dobbernack, Simone Florian, Wolfram Engst

Chem Res Toxicol· June 2014

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Formation of hepatic DNA adducts by methyleugenol in mouse models: drastic decrease by Sult1a1 knockout and strong increase by transgenic human SULT1A1/2.
Kristin Herrmann, Wolfram Engst, Walter Meinl, Simone Florian, Alexander T Cartus

Carcinogenesis· April 2014

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A secondary metabolite of Brassicales, 1-methoxy-3-indolylmethyl glucosinolate, as well as its degradation product, 1-methoxy-3-indolylmethyl alcohol, forms DNA adducts in the mouse, but in varying tissues and cells.
Fabian Schumacher, Simone Florian, Anke Schnapper, Bernhard H Monien, Inga Mewis, Wolfram Engst

Arch Toxicol· March 2014

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Identification and quantification of protein adducts formed by metabolites of 1-methoxy-3-indolylmethyl glucosinolate in vitro and in mouse models.
Gitte Barknowitz, Wolfram Engst, Stephan Schmidt, Mareike Bernau, Bernhard H Monien

Chem Res Toxicol· February 2014

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Identification and expression of genes involved in the conversion of daidzein and genistein by the equol-forming bacterium Slackia isoflavoniconvertens.
Christine Schröder, Anastasia Matthies, Wolfram Engst, Michael Blaut, Annett Braune

Appl Environ Microbiol· June 2013

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Abundance of DNA adducts of methyleugenol, a rodent hepatocarcinogen, in human liver samples.
Kristin Herrmann, Fabian Schumacher, Wolfram Engst, Klaus E Appel, Kathrin Klein

Carcinogenesis· May 2013

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Contribution of gut bacteria to the metabolism of cyanidin 3-glucoside in human microbiota-associated rats.
Laura Hanske, Wolfram Engst, Gunnar Loh, Silke Sczesny, Michael Blaut

Br J Nutr· April 2013

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Optimized enzymatic hydrolysis of DNA for LC-MS/MS analyses of adducts of 1-methoxy-3-indolylmethyl glucosinolate and methyleugenol.
Fabian Schumacher, Kristin Herrmann, Simone Florian, Wolfram Engst, Hansruedi Glatt

Anal Biochem· March 2013

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Metabolism of methyleugenol in liver microsomes and primary hepatocytes: pattern of metabolites, cytotoxicity, and DNA-adduct formation.
Alexander T Cartus, Kristin Herrmann, Lucas W Weishaupt, Karl-Heinz Merz, Wolfram Engst

Toxicol Sci· September 2012

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Identification of human and murine sulfotransferases able to activate hydroxylated metabolites of methyleugenol to mutagens in Salmonella typhimurium and detection of associated DNA adducts using UPLC-MS/MS methods.
Kristin Herrmann, Wolfram Engst, Klaus E Appel, Bernhard H Monien, Hansruedi Glatt

Mutagenesis· July 2012

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Mutagenicity of 5-hydroxymethylfurfural in V79 cells expressing human SULT1A1: identification and mass spectrometric quantification of DNA adducts formed.
Bernhard H Monien, Wolfram Engst, Gitte Barknowitz, Albrecht Seidel, Hansruedi Glatt

Chem Res Toxicol· July 2012

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Detection of DNA adducts originating from 1-methoxy-3-indolylmethyl glucosinolate using isotope-dilution UPLC-ESI-MS/MS.
Fabian Schumacher, Wolfram Engst, Bernhard H Monien, Simone Florian, Anke Schnapper

Anal Chem· July 2012

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Impact of nutritional factors on the proteome of intestinal Escherichia coli: induction of OxyR-dependent proteins AhpF and Dps by a lactose-rich diet.
Monique Rothe, Carl Alpert, Wolfram Engst, Stephanie Musiol, Gunnar Loh

Appl Environ Microbiol· May 2012

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Dextran sodium sulfate-induced inflammation alters the expression of proteins by intestinal Escherichia coli strains in a gnotobiotic mouse model.
Sara Schumann, Carl Alpert, Wolfram Engst, Gunnar Loh, Michael Blaut

Appl Environ Microbiol· March 2012

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1-Methoxy-3-indolylmethyl glucosinolate; a potent genotoxicant in bacterial and mammalian cells: Mechanisms of bioactivation.
Hansruedi Glatt, Chimgee Baasanjav-Gerber, Fabian Schumacher, Bernhard H Monien, Monika Schreiner, Wolfram Engst

Chem Biol Interact· June 2011

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Requirement of purine and pyrimidine synthesis for colonization of the mouse intestine by Escherichia coli.
Jacqueline Vogel-Scheel, Carl Alpert, Wolfram Engst, Gunnar Loh, Michael Blaut

Appl Environ Microbiol· August 2010

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Adaptation of protein expression by Escherichia coli in the gastrointestinal tract of gnotobiotic mice.
Carl Alpert, Jacqueline Scheel, Wolfram Engst, Gunnar Loh, Michael Blaut

Environ Microbiol· April 2009

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Time course of hepatic 1-methylpyrene DNA adducts in rats determined by isotope dilution LC-MS/MS and 32P-postlabeling.
Bernhard H Monien, Carolin Müller, Wolfram Engst, Heinz Frank, Albrecht Seidel

Chem Res Toxicol· October 2008

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Conversion of daidzein and genistein by an anaerobic bacterium newly isolated from the mouse intestine.
Anastasia Matthies, Thomas Clavel, Michael Gütschow, Wolfram Engst, Dirk Haller

Appl Environ Microbiol· August 2008

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