Publications by authors named "Simone Spuler"

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Advanced peptide nanoparticles enable robust and efficient delivery of gene editors across cell types.
Oskar Gustafsson, Supriya Krishna, Sophia Borate, Marziyeh Ghaeidamini, Xiuming Liang, Simone Spuler

J Control Release· October 2025

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High-Density Lipoprotein-Associated Cholesterol Abnormalities in a Clinical Outcomes Study of Dysferlin-Deficient Limb-Girdle Muscular Dystrophy Type R2.
Zoe White, Laura Rufibach, Heather Gordish Dressman, Heather Hilsden, Dan Cox, Simone Spuler

J Cachexia Sarcopenia Muscle· August 2025

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Lessons from a negative gene therapy trial for Duchenne muscular dystrophy.
Simone Spuler, Gian Domenico Borasio, Ulrike Grittner

Nat Med· January 2025

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Gene-editing in patient and humanized-mice primary muscle stem cells rescues dysferlin expression in dysferlin-deficient muscular dystrophy.
Helena Escobar, Silvia Di Francescantonio, Julia Smirnova, Robin Graf, Stefanie Müthel, Simone Spuler

Nat Commun· January 2025

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Undetected Neuromuscular Disease in Patients after Heart Transplantation.
Biniam Melese Bekele, Elisabetta Gazzerro, Felix Schoenrath, Volkmar Falk, Simone Rost, Simone Spuler

Int J Mol Sci· July 2024

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Development and systematic evaluation of decellularization protocols in different application models for diaphragmatic tissue engineering.
Marco N Andreas, Agnes K Boehm, Peter Tang, Simon Moosburner, Oliver Klein, Simone Spuler

Biomater Adv· October 2023

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Cas9-induced single cut enables highly efficient and template-free repair of a muscular dystrophy causing founder mutation.
Stefanie Müthel, Andreas Marg, Busem Ignak, Janine Kieshauer, Helena Escobar, Simone Spuler

Mol Ther Nucleic Acids· March 2023

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Corrigendum: Exercise blood-drop metabolic profiling links metabolism with perceived exertion.
Tobias Opialla, Benjamin Gollasch, Peter H J L Kuich, Lars Klug, Gabriele Rahn, Simone Spuler

Front Mol Biosci· March 2023

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Disintegration of the NuRD Complex in Primary Human Muscle Stem Cells in Critical Illness Myopathy.
Joanna Schneider, Devakumar Sundaravinayagam, Alexander Blume, Andreas Marg, Stefanie Grunwald, Simone Spuler

Int J Mol Sci· February 2023

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"suMus," a novel digital system for arm movement metrics and muscle energy expenditure.
Teresa Gerhalter, Christina Müller, Elke Maron, Markus Thielen, Teresa Schätzl, Simone Spuler

Front Physiol· January 2023

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Co-Regulated Gene Expression as a Suitable Readout after Precise Gene Correction.
Haicui Wang, Anne Krause, Helena Escobar, Stefanie Müthel, Eric Metzler, Simone Spuler

Int J Mol Sci· December 2022

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Exercise blood-drop metabolic profiling links metabolism with perceived exertion.
Tobias Opialla, Benjamin Gollasch, Peter H J L Kuich, Lars Klug, Gabriele Rahn, Simone Spuler

Front Mol Biosci· December 2022

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Human primary muscle stem cells regenerate injured urethral sphincter in athymic rats.
Biniam M Bekele, Verena Schöwel-Wolf, Janine Kieshauer, Andreas Marg, Andreas Busjahn, Simone Spuler

Animal Model Exp Med· October 2022

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Therapeutic targeting of ATR in alveolar rhabdomyosarcoma.
Heathcliff Dorado García, Fabian Pusch, Yi Bei, Jennifer von Stebut, Glorymar Ibáñez, Simone Spuler

Nat Commun· July 2022

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mRNA-mediated delivery of gene editing tools to human primary muscle stem cells.
Christian Stadelmann, Silvia Di Francescantonio, Andreas Marg, Stefanie Müthel, Simone Spuler

Mol Ther Nucleic Acids· June 2022

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Cardiac and pulmonary findings in dysferlinopathy: A 3-year, longitudinal study.
Ursula Moore, Roberto Fernandez-Torron, Marni Jacobs, Heather Gordish-Dressman, Jordi Diaz-Manera, Simone Spuler

Muscle Nerve· May 2022

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Myofibrillar protein synthesis rates are increased in chronically exercised skeletal muscle despite decreased anabolic signaling.
Henning T Langer, Daniel West, Joan Senden, Simone Spuler, Luc J C van Loon

Sci Rep· May 2022

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Generation of hiPSC-Derived Skeletal Muscle Cells: Exploiting the Potential of Skeletal Muscle-Derived hiPSCs.
Eric Metzler, Helena Escobar, Daniele Yumi Sunaga-Franze, Sascha Sauer, Sebastian Diecke, Simone Spuler

Biomedicines· May 2022

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Assessing the Relationship of Patient Reported Outcome Measures With Functional Status in Dysferlinopathy: A Rasch Analysis Approach.
Anna G Mayhew, Meredith K James, Ursula Moore, Helen Sutherland, Marni Jacobs, Simone Spuler

Front Neurol· March 2022

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Statins Aggravate the Risk of Insulin Resistance in Human Muscle.
Stefanie A Grunwald, Stefanie Haafke, Ulrike Grieben, Ursula Kassner, Elisabeth Steinhagen-Thiessen, Simone Spuler

Int J Mol Sci· February 2022

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4-Phenylbutyrate restores localization and membrane repair to human dysferlin mutations.
Kana Tominaga, Naoomi Tominaga, Eric O Williams, Laura Rufibach, Verena Schöwel, Simone Spuler

iScience· January 2022

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Progressive myocardial injury in myotonic dystrophy type II and facioscapulohumeral muscular dystrophy 1: a cardiovascular magnetic resonance follow-up study.
Edyta Blaszczyk, Carolin Lim, Peter Kellman, Luisa Schmacht, Jan Gröschel, Simone Spuler

J Cardiovasc Magn Reson· November 2021

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[Diagnostics and treatment of statin-associated muscle symptoms].
Ursula Kassner, Stefanie Grunwald, Dominik Spira, Nikolaus Buchmann, Thomas Bobbert, Simone Spuler

Internist (Berl)· August 2021

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Myogenic Cell Transplantation in Genetic and Acquired Diseases of Skeletal Muscle.
Olivier Boyer, Gillian Butler-Browne, Hector Chinoy, Giulio Cossu, Francesco Galli, Simone Spuler

Front Genet· August 2021

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Base editing repairs an SGCA mutation in human primary muscle stem cells.
Helena Escobar, Anne Krause, Sandra Keiper, Janine Kieshauer, Stefanie Müthel, Simone Spuler

JCI Insight· May 2021

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