Publications by authors named "Simone Thum"

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A common mechanism allows selective targeting of GluN2B subunit-containing -methyl-D-aspartate receptors.
Julian A Schreiber, Dirk Schepmann, Bastian Frehland, Simone Thum, Maia Datunashvili

Commun Biol· May 2020

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Tetrahydro-3-benzazepines with fluorinated side chains as NMDA and σ receptor antagonists: Synthesis, receptor affinity, selectivity and antiallodynic activity.
Simone Thum, Dirk Schepmann, Eva Ayet, Marta Pujol, Francisco R Nieto

Eur J Med Chem· September 2019

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Synthesis and pharmacological evaluation of fluorinated benzo[7]annulen-7-amines as GluN2B-selective NMDA receptor antagonists.
Simone Thum, Dirk Schepmann, Raquel F Reinoso, Inés Alvarez, Simon M Ametamey

J Labelled Comp Radiopharm· June 2019

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Replacement of the Benzylpiperidine Moiety with Fluorinated Phenylalkyl Side Chains for the Development of GluN2B Receptor Ligands.
Simone Thum, Dirk Schepmann, Dmitrii V Kalinin, Simon M Ametamey, Bernhard Wünsch

ChemMedChem· December 2018

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Synthesis, Receptor Affinity, and Antiallodynic Activity of Spirocyclic σ Receptor Ligands with Exocyclic Amino Moiety.
Melanie Bergkemper, Elisabeth Kronenberg, Simone Thum, Frederik Börgel, Constantin Daniliuc

J Med Chem· November 2018

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Synthesis and biological evaluation of chemokine receptor ligands with 2-benzazepine scaffold.
Simone Thum, Artur K Kokornaczyk, Tomoaki Seki, Monica De Maria, Natalia V Ortiz Zacarias

Eur J Med Chem· July 2017

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Do GluN2B subunit containing NMDA receptors tolerate a fluorine atom in the phenylalkyl side chain?
Yoshihiro Shuto, Simone Thum, Louisa Temme, Dirk Schepmann, Masato Kitamura

Medchemcomm· May 2017

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