Publications by authors named "Spencer Dech"

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Improved translation of Na1.5 channel inhibition to in vivo QRS interval prolongation via the hIPSC cardiomyocyte model.
John P Imredy, Holly Clouse, Mei Zhang, Spencer Dech, Qiuwei Xu

J Pharmacol Toxicol Methods· September 2025

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Interaction between amiodarone and hepatitis-C virus nucleotide inhibitors in human induced pluripotent stem cell-derived cardiomyocytes and HEK-293 Cav1.2 over-expressing cells.
Armando Lagrutta, Haoyu Zeng, John Imredy, Bharathi Balasubramanian, Spencer Dech

Toxicol Appl Pharmacol· October 2016

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Vasoprotective endothelial effects of a standardized grape product in humans.
Alysia A Chaves, Mandar S Joshi, Christen M Coyle, Joshua E Brady, Spencer J Dech

Vascul Pharmacol· April 2009

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Modeling of the adrenergic response of the human IKs current (hKCNQ1/hKCNE1) stably expressed in HEK-293 cells.
John P Imredy, Jacob R Penniman, Spencer J Dech, Winston D Irving, Joseph J Salata

Am J Physiol Heart Circ Physiol· November 2008

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Improved throughput of PatchXpress hERG assay using intracellular potassium fluoride.
Haoyu Zeng, Jacob R Penniman, Fumi Kinose, David Kim, Elena S Trepakova, Spencer J Dech

Assay Drug Dev Technol· April 2008

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Application of PatchXpress planar patch clamp technology to the screening of new drug candidates for cardiac KCNQ1/KCNE1 (I Ks) activity.
Elena S Trepakova, Manish G Malik, John P Imredy, Jacob R Penniman, Spencer J Dech

Assay Drug Dev Technol· October 2007

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Abnormal diastolic currents in ventricular myocytes from spontaneous hypertensive heart failure rats.
Arun Sridhar, Spencer J Dech, Veronique A Lacombe, Terry S Elton, Sylvia A McCune

Am J Physiol Heart Circ Physiol· November 2006

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Flunarizine is a highly potent inhibitor of cardiac hERG potassium current.
Elena S Trepakova, Spencer J Dech, Joseph J Salata

J Cardiovasc Pharmacol· February 2006

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Age and anesthetic effects on murine electrocardiography.
Alysia A Chaves, Spencer J Dech, Tomohiro Nakayama, Robert L Hamlin, John Anthony Bauer

Life Sci· April 2003

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Effects of dihydrotestosterone on cardiac inward rectifier K(+) current.
Cynthia A Carnes, Spencer J Dech

Int J Androl· August 2002

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