Publications by authors named "Stefan Hart"

Claim this Profile
V
VS-5584 mediates potent anti-myeloma activity via the upregulation of a class II tumor suppressor gene, RARRES3 and the activation of Bim.
Nurulhuda Mustafa, Jeannie Xue Ting Lee, Huey Fang Adina Nee, Chonglei Bi, Tae-Hoon Chung, Stefan Hart

Oncotarget· November 2017

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
E
Effect of Ang-2-VEGF-A Bispecific Antibody in Renal Cell Carcinoma.
Hideharu Bessho, Bernice Wong, Dachuan Huang, Jing Tan, Choon Kiat Ong, Stefan Hart

Cancer Invest· April 2016

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Structure and ligand-based design of mTOR and PI3-kinase inhibitors leading to the clinical candidates VS-5584 (SB2343) and SB2602.
Anders Poulsen, Harish Nagaraj, Angeline Lee, Stéphanie Blanchard, Chang Kai Soh, Stefan Hart

J Chem Inf Model· November 2014

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Scalable spheroid model of human hepatocytes for hepatitis C infection and replication.
Abhishek Ananthanarayanan, Bramasta Nugraha, Miriam Triyatni, Stefan Hart, Suryanarayana Sankuratri

Mol Pharm· July 2014

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
R
Reduction of HBV replication prolongs the early immunological response to IFNα therapy.
Anthony T Tan, Long Truong Hoang, Daniel Chin, Erik Rasmussen, Uri Lopatin, Stefan Hart

J Hepatol· January 2014

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
V
VS-5584, a novel and highly selective PI3K/mTOR kinase inhibitor for the treatment of cancer.
Stefan Hart, Veronica Novotny-Diermayr, Kee Chuan Goh, Meredith Williams, Yong Cheng Tan

Mol Cancer Ther· February 2013

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
P
Phase I study of a novel oral Janus kinase 2 inhibitor, SB1518, in patients with relapsed lymphoma: evidence of clinical and biologic activity in multiple lymphoma subtypes.
Anas Younes, Jorge Romaguera, Michelle Fanale, Peter McLaughlin, Frederick Hagemeister, Stefan Hart

J Clin Oncol· November 2012

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
SB1578, a novel inhibitor of JAK2, FLT3, and c-Fms for the treatment of rheumatoid arthritis.
Babita Madan, Kee Chuan Goh, Stefan Hart, Anthony D William, Ramesh Jayaraman

J Immunol· October 2012

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Discovery of the macrocycle (9E)-15-(2-(pyrrolidin-1-yl)ethoxy)-7,12,25-trioxa-19,21,24-triaza-tetracyclo[18.3.1.1(2,5).1(14,18)]hexacosa-1(24),2,4,9,14(26),15,17,20,22-nonaene (SB1578), a potent inhibitor of janus kinase 2/fms-like tyrosine kinase-3 (JAK2/FLT3) for the treatment of rheumatoid arthritis.
Anthony D William, Angeline C-H Lee, Anders Poulsen, Kee Chuan Goh, Babita Madan, Stefan Hart

J Med Chem· March 2012

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Discovery of the macrocycle 11-(2-pyrrolidin-1-yl-ethoxy)-14,19-dioxa-5,7,26-triaza-tetracyclo[19.3.1.1(2,6).1(8,12)]heptacosa-1(25),2(26),3,5,8,10,12(27),16,21,23-decaene (SB1518), a potent Janus kinase 2/fms-like tyrosine kinase-3 (JAK2/FLT3) inhibitor for the treatment of myelofibrosis and lymphoma.
Anthony D William, Angeline C-H Lee, Stéphanie Blanchard, Anders Poulsen, Ee Ling Teo, Stefan Hart

J Med Chem· July 2011

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
SB939, a novel potent and orally active histone deacetylase inhibitor with high tumor exposure and efficacy in mouse models of colorectal cancer.
Veronica Novotny-Diermayr, Kanda Sangthongpitag, Chang Yong Hu, Xiaofeng Wu, Nina Sausgruber, Stefan Hart

Mol Cancer Ther· March 2010

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
F
Fibroblast growth factor receptor 4 regulates proliferation, anti-apoptosis and alpha-fetoprotein secretion during hepatocellular carcinoma progression and represents a potential target for therapeutic intervention.
Han Kiat Ho, Sharon Pok, Sylvia Streit, Jens E Ruhe, Stefan Hart

J Hepatol· January 2009

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
G
Genetic alterations in the tyrosine kinase transcriptome of human cancer cell lines.
Jens E Ruhe, Sylvia Streit, Stefan Hart, Chee-Hong Wong, Katja Specht

Cancer Res· December 2007

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
E
EGFR signaling leads to downregulation of PTP-LAR via TACE-mediated proteolytic processing.
Jens E Ruhe, Sylvia Streit, Stefan Hart, Axel Ullrich

Cell Signal· September 2006

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Dissecting the epidermal growth factor receptor signal transactivation pathway.
Oliver M Fischer, Stefan Hart, Axel Ullrich

Methods Mol Biol· July 2006

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
G
GPCR-induced migration of breast carcinoma cells depends on both EGFR signal transactivation and EGFR-independent pathways.
Stefan Hart, Oliver M Fischer, Norbert Prenzel, Esther Zwick-Wallasch, Matthias Schneider

Biol Chem· September 2005

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
M
Mammary gland remodeling depends on gp130 signaling through Stat3 and MAPK.
Ling Zhao, Stefan Hart, JrGang Cheng, J Joseph Melenhorst, Brian Bierie

J Biol Chem· October 2004

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
O
Oxidative and osmotic stress signaling in tumor cells is mediated by ADAM proteases and heparin-binding epidermal growth factor.
Oliver M Fischer, Stefan Hart, Andreas Gschwind, Norbert Prenzel, Axel Ullrich

Mol Cell Biol· June 2004

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
Cannabinoids induce cancer cell proliferation via tumor necrosis factor alpha-converting enzyme (TACE/ADAM17)-mediated transactivation of the epidermal growth factor receptor.
Stefan Hart, Oliver M Fischer, Axel Ullrich

Cancer Res· March 2004

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
B
Beyond Herceptin and Gleevec.
Oliver M Fischer, Sylvia Streit, Stefan Hart, Axel Ullrich

Curr Opin Chem Biol· August 2003

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
TACE cleavage of proamphiregulin regulates GPCR-induced proliferation and motility of cancer cells.
Andreas Gschwind, Stefan Hart, Oliver M Fischer, Axel Ullrich

EMBO J· May 2003

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis