Publications by authors named "Stepan Kortus"

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Distinct Regulation of Early Trafficking of the NMDA Receptors by the Ligand-Binding Domains of the GluN1 and GluN2A Subunits.
Jakub Netolicky, Petra Zahumenska, Anna Misiachna, Marharyta Kolcheva, Kristyna Rehakova, Stepan Kortus

J Neurosci· June 2025

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Potent and reversible open-channel blocker of NMDA receptor derived from dizocilpine with enhanced membrane-to-channel inhibition.
Anna Misiachna, Jan Konecny, Marharyta Kolcheva, Marek Ladislav, Lukas Prchal, Stepan Kortus

Biomed Pharmacother· September 2024

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Subunit-Dependent Surface Mobility and Localization of NMDA Receptors in Hippocampal Neurons Measured Using Nanobody Probes.
Stepan Kortus, Kristyna Rehakova, Martin Klima, Marharyta Kolcheva, Marek Ladislav

J Neurosci· June 2023

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The pathogenic N650K variant in the GluN1 subunit regulates the trafficking, conductance, and pharmacological properties of NMDA receptors.
Marharyta Kolcheva, Marek Ladislav, Jakub Netolicky, Stepan Kortus, Kristyna Rehakova

Neuropharmacology· January 2023

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Structure-activity relationships of dually-acting acetylcholinesterase inhibitors derived from tacrine on N-methyl-d-Aspartate receptors.
Lukas Gorecki, Anna Misiachna, Jiri Damborsky, Rafael Dolezal, Jan Korabecny, Stepan Kortus

Eur J Med Chem· July 2021

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Specific pathogenic mutations in the M3 domain of the GluN1 subunit regulate the surface delivery and pharmacological sensitivity of NMDA receptors.
Marharyta Kolcheva, Stepan Kortus, Barbora Hrcka Krausova, Petra Barackova, Anna Misiachna

Neuropharmacology· May 2021

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Pursuing the Complexity of Alzheimer's Disease: Discovery of Fluoren-9-Amines as Selective Butyrylcholinesterase Inhibitors and -Methyl-d-Aspartate Receptor Antagonists.
Jan Konecny, Anna Misiachna, Martina Hrabinova, Lenka Pulkrabkova, Marketa Benkova, Stepan Kortus

Biomolecules· December 2020

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The pathogenic S688Y mutation in the ligand-binding domain of the GluN1 subunit regulates the properties of NMDA receptors.
Kristyna Skrenkova, Jae-Man Song, Stepan Kortus, Marharyta Kolcheva, Jakub Netolicky

Sci Rep· October 2020

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Structural features in the glycine-binding sites of the GluN1 and GluN3A subunits regulate the surface delivery of NMDA receptors.
Kristyna Skrenkova, Katarina Hemelikova, Marharyta Kolcheva, Stepan Kortus, Martina Kaniakova

Sci Rep· August 2019

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Sodium-calcium exchanger and R-type Ca(2+) channels mediate spontaneous [Ca(2+)]i oscillations in magnocellular neurones of the rat supraoptic nucleus.
Stepan Kortus, Chinnapaiyan Srinivasan, Oksana Forostyak, Martin Zapotocky, Yoichi Ueta

Cell Calcium· June 2016

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Physiology of spontaneous [Ca(2+)]i oscillations in the isolated vasopressin and oxytocin neurones of the rat supraoptic nucleus.
Stepan Kortus, Chinnapaiyan Srinivasan, Oksana Forostyak, Yoichi Ueta, Eva Sykova

Cell Calcium· June 2016

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Physiology of Ca(2+) signalling in stem cells of different origins and differentiation stages.
Oksana Forostyak, Serhiy Forostyak, Stepan Kortus, Eva Sykova, Alexei Verkhratsky

Cell Calcium· March 2016

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