Publications by authors named "Stephan Buchmann"

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Characterization of Novel Antimalarial Compound ACT-451840: Preclinical Assessment of Activity and Dose-Efficacy Modeling.
Amélie Le Bihan, Ruben de Kanter, Iñigo Angulo-Barturen, Christoph Binkert, Christoph Boss, Stephan Buchmann

PLoS Med· October 2016

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Physiologically-Based Pharmacokinetic Modeling of Macitentan: Prediction of Drug-Drug Interactions.
Ruben de Kanter, Patricia N Sidharta, Stéphane Delahaye, Carmela Gnerre, Jerome Segrestaa, Stephan Buchmann

Clin Pharmacokinet· March 2016

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The discovery of N-[5-(4-bromophenyl)-6-[2-[(5-bromo-2-pyrimidinyl)oxy]ethoxy]-4-pyrimidinyl]-N'-propylsulfamide (Macitentan), an orally active, potent dual endothelin receptor antagonist.
Martin H Bolli, Christoph Boss, Christoph Binkert, Stephan Buchmann, Daniel Bur

J Med Chem· September 2012

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2-imino-thiazolidin-4-one derivatives as potent, orally active S1P1 receptor agonists.
Martin H Bolli, Stefan Abele, Christoph Binkert, Roberto Bravo, Stephan Buchmann

J Med Chem· May 2010

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Pharmacology of macitentan, an orally active tissue-targeting dual endothelin receptor antagonist.
Marc Iglarz, Christoph Binkert, Keith Morrison, Walter Fischli, John Gatfield, Stephan Buchmann

J Pharmacol Exp Ther· December 2008

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Promotion of sleep by targeting the orexin system in rats, dogs and humans.
Catherine Brisbare-Roch, Jasper Dingemanse, Ralf Koberstein, Petra Hoever, Hamed Aissaoui, Stephan Buchmann

Nat Med· February 2007

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Novel benzo[1,4]diazepin-2-one derivatives as endothelin receptor antagonists.
Martin H Bolli, Judith Marfurt, Corinna Grisostomi, Christoph Boss, Christoph Binkert, Stephan Buchmann

J Med Chem· May 2004

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