Publications by authors named "Stephan Dickgiesser"

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FlexTORCH: An Improved Flexible Fluorophore-Linker-Quencher Molecule Enlightening ADC Research.
Tim Neumann, Katrin Schreiber, Min Shan, Nicolas Rasche, Stephan Dickgiesser

Bioconjug Chem· September 2025

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Elucidating Critical Factors of Internalization and Drug Release of Antibody-Drug Conjugates (ADCs) Using Kinetic Parameters Evaluated by a Novel Tool Named TORCH.
Stanley Sweeney-Lasch, Marie Quillmann, Jens Hannewald, Stephan Dickgiesser, Nicolas Rasche

Bioconjug Chem· May 2025

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Welding PROxAb Shuttles: A Modular Approach for Generating Bispecific Antibodies via Site-Specific Protein-Protein Conjugation.
Tanja Lehmann, Hendrik Schneider, Jason Tonillo, Jennifer Schanz, Daniel Schwarz, Stephan Dickgiesser

Bioconjug Chem· June 2024

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Potent antitumor activity of anti-HER2 antibody-topoisomerase I inhibitor conjugate based on self-immolative dendritic dimeric-linker.
Yulia Liubomirski, Galia Tiram, Anna Scomparin, Samer Gnaim, Sayantan Das, Stephan Dickgiesser

J Control Release· March 2024

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A Generic Approach for Miniaturized Unbiased High-Throughput Screens of Bispecific Antibodies and Biparatopic Antibody-Drug Conjugates.
Nadine Barron, Stephan Dickgiesser, Markus Fleischer, Angelika-Nicole Bachmann, Daniel Klewinghaus

Int J Mol Sci· February 2024

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From strain engineering to process development: monoclonal antibody production with an unnatural amino acid in Pichia pastoris.
Nora Tir, Lina Heistinger, Clemens Grünwald-Gruber, Leo A Jakob, Stephan Dickgiesser

Microb Cell Fact· August 2022

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Efficient spontaneous site-selective cysteine-mediated toxin attachment within a structural loop of antibodies.
Gerhard Stadlmayr, Florian Stracke, Katharina Stadlbauer, Jakub Rybka, Stephan Dickgiesser

Biochim Biophys Acta Gen Subj· July 2022

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EGFR binding Fc domain-drug conjugates: stable and highly potent cytotoxic molecules mediate selective cell killing.
Sebastian Jäger, Stephan Dickgiesser, Jason Tonillo, Stefan Hecht, Harald Kolmar

Biol Chem· April 2022

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Effect of Conjugation Site and Technique on the Stability and Pharmacokinetics of Antibody-Drug Conjugates.
Anna Kaempffe, Stephan Dickgiesser, Nicolas Rasche, Andrea Paoletti, Elisa Bertotti

J Pharm Sci· December 2021

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Isolation of Anti-Hapten Antibodies by Fluorescence-Activated Cell Sorting of Yeast-Displayed B-Cell Receptor Gene Repertoires.
Sebastian Jäger, Simon Krah, Doreen Könning, Janis Rosskopf, Stephan Dickgiesser

Methods Mol Biol· December 2020

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Site-Specific Conjugation of Thiol-Reactive Cytotoxic Agents to Nonnative Cysteines of Engineered Monoclonal Antibodies.
Stephan Dickgiesser, Roland Kellner, Harald Kolmar, Nicolas Rasche

Methods Mol Biol· April 2020

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Site-Specific Conjugation of Native Antibodies Using Engineered Microbial Transglutaminases.
Stephan Dickgiesser, Marcel Rieker, Dirk Mueller-Pompalla, Christian Schröter, Jason Tonillo

Bioconjug Chem· April 2020

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Site-Specific Antibody-Drug Conjugation Using Microbial Transglutaminase.
Stephan Dickgiesser, Lukas Deweid, Roland Kellner, Harald Kolmar, Nicolas Rasche

Methods Mol Biol· March 2020

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Sortagged anti-EGFR immunoliposomes exhibit increased cytotoxicity on target cells.
Steffen Wöll, Stephan Dickgiesser, Nicolas Rasche, Stefan Schiller, Regina Scherließ

Eur J Pharm Biopharm· March 2019

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Engineering bispecific antibodies with defined chain pairing.
Simon Krah, Carolin Sellmann, Laura Rhiel, Christian Schröter, Stephan Dickgiesser

N Biotechnol· October 2017

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Semi-synthetic vNAR libraries screened against therapeutic antibodies primarily deliver anti-idiotypic binders.
Doreen Könning, Laura Rhiel, Martin Empting, Julius Grzeschik, Carolin Sellmann

Sci Rep· August 2017

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An Apoptosis-Inducing Peptidic Heptad That Efficiently Clusters Death Receptor 5.
Bernhard Valldorf, Heiko Fittler, Lukas Deweid, Aileen Ebenig, Stephan Dickgiesser

Angew Chem Int Ed Engl· April 2016

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Locked by Design: A Conformationally Constrained Transglutaminase Tag Enables Efficient Site-Specific Conjugation.
Vanessa Siegmund, Stefan Schmelz, Stephan Dickgiesser, Jan Beck, Aileen Ebenig

Angew Chem Int Ed Engl· November 2015

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Self-Assembled Hybrid Aptamer-Fc Conjugates for Targeted Delivery: A Modular Chemoenzymatic Approach.
Stephan Dickgiesser, Nicolas Rasche, Daichi Nasu, Stephen Middel, Sebastian Hörner

ACS Chem Biol· September 2015

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Cystine-knot peptides targeting cancer-relevant human cytotoxic T lymphocyte-associated antigen 4 (CTLA-4).
Franziska Maaß, Joycelyn Wüstehube-Lausch, Stephan Dickgießer, Bernhard Valldorf, Michael Reinwarth

J Pept Sci· August 2015

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The Shark Strikes Twice: Hypervariable Loop 2 of Shark IgNAR Antibody Variable Domains and Its Potential to Function as an Autonomous Paratope.
Stefan Zielonka, Martin Empting, Doreen Könning, Julius Grzeschik, Simon Krah

Mar Biotechnol (NY)· August 2015

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