Publications by authors named "Stephane Bach"

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Sibiriline, a novel dual inhibitor of necroptosis and ferroptosis, prevents RIPK1 kinase activity and (phospho)lipid peroxidation as a potential therapeutic strategy.
Claire Delehouzé, Melodie Mallais, Arnaud Comte, Romain Lucas, Blandine Baratte, Stéphane Bach

Cell Death Discov· November 2025

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Research towards selective inhibition of the CLK3 kinase.
Vinay Kumar Singh, Frédéric Justaud, Dabbugoddu Brahmaiah, Nangunoori Sampath Kumar, Blandine Baratte, Stéphane Bach

Beilstein J Org Chem· October 2025

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Pharmacophore-guided optimization of the hit compound CTN1122 in the design of promising imidazo[1,2-]pyrazine derivatives targeting the casein kinase 1 for antileishmanial therapy.
Lhana Tisseur, Cédric Logé, Sandrine Cojean, Khadidiatou Gassama, Lilian Karcher, Stéphane Bach

RSC Med Chem· June 2025

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New Insights into the Anticancer Effects and Toxicogenomic Safety of Two β-Lapachone Derivatives.
José Rivaldo De Lima, Alexandre José Da Silva Góes, Elizabeth Fernanda De Oliveira Borba, Meykson Alexandre da Silva, Rodrigo Ribeiro Alves Caiana, Stéphane Bach

Pharmaceuticals (Basel)· June 2025

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Development of a novel family of antifungal agents based on a quinone methide oxime framework.
Monika Janeczko, Maciej Masłyk, Oleg M Demchuk, Antonina Kurowska-Okoń, Mateusz Kwaśnik, Stéphane Bach

Sci Rep· April 2025

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Investigating the C2 Modulation of the Imidazo[1,2-a]pyrazine-Based Hit Compound CTN1122: Synthesis, in vitro Antileishmanial Activity, Cytotoxicity and Casein Kinase 1 Inhibition.
Lhana Tisseur, Sandrine Cojean, Khadidiatou Gassama, Cédric Logé, Fabrice Pagniez, Stéphane Bach

ChemMedChem· March 2025

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XPS Investigation of Co-Ni Oxidized Compounds Surface Using Peak-On-Satellite Ratio. Application to CoNi Passive Layer Structure and Composition.
Barbara Laïk, Morgane Richet, Nicolas Emery, Stephane Bach, Loïc Perrière

ACS Omega· October 2024

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Novel Thiazole-Fused [4,5-] or [5,4-]Quinazolin-8-ones and Their Quinazoline Analogues: Synthesis and Biological Evaluation.
Nathan Broudic, Alexandra Pacheco-Benichou, Cécile Corbière, Blandine Baratte, Thomas Robert, Stéphane Bach

Pharmaceuticals (Basel)· October 2024

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New Fusarochromanone Derivatives from the Marine Fungus UBOCC-A-117302.
Giang Nam Pham, Béatrice Josselin, Arnaud Cousseau, Blandine Baratte, Marie Dayras, Stéphane Bach

Mar Drugs· September 2024

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Ethaverine and Papaverine Target Cyclin-Dependent Kinase 5 and Inhibit Lung Cancer Cell Proliferation and Migration.
Arthur Laure, Chloé Royet, Frederic Bihel, Blandine Baratte, Stéphane Bach

ACS Pharmacol Transl Sci· May 2024

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Quinazoline-based VEGFR-2 inhibitors as potential anti-angiogenic agents: A contemporary perspective of SAR and molecular docking studies.
Mahfam Moradi, Alireza Mousavi, Zahra Emamgholipour, Johanna Giovannini, Setareh Moghimi, Stéphane Bach

Eur J Med Chem· November 2023

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Overexpression of Eimeria tenella Rhoptry Kinase 2 Induces Early Production of Schizonts.
Adeline Ribeiro E Silva, Mamadou Amadou Diallo, Alix Sausset, Thomas Robert, Stéphane Bach

Microbiol Spectr· August 2023

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Oxazolo[5,4-f]quinoxaline-type selective inhibitors of glycogen synthase kinase-3α (GSK-3α): Development and impact on temozolomide treatment of glioblastoma cells.
Mohamed Hasyeoui, Frédéric Lassagne, William Erb, Manal Nael, Khaled M Elokely, Stéphane Bach

Bioorg Chem· May 2023

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Identification of Novel Compounds Inhibiting the Kinase Activity of the CDK5/p25 Complex via Direct Binding to p25.
Riheb Jabeur, Caroline Corbel, Pascal Loyer, Annabelle Le Parc, Adélaide Le Grand, Stéphane Bach

Biochemistry· May 2023

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Imidazo[1,2-a]quinazolines as novel, potent EGFR-TK inhibitors: Design, synthesis, bioactivity evaluation, and in silico studies.
Zaman Hasanvand, Tayebeh Oghabi Bakhshaiesh, Fariba Peytam, Loghman Firoozpour, Elaheh Hosseinzadeh, Stéphane Bach

Bioorg Chem· April 2023

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Design and biological evaluation of substituted 5,7-dihydro-6-indolo[2,3-]quinolin-6-one as novel selective Haspin inhibitors.
Sreenivas Avula, Xudan Peng, Xingfen Lang, Micky Tortorella, Béatrice Josselin, Stéphane Bach

J Enzyme Inhib Med Chem· December 2022

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An Optimized Workflow for the Discovery of New Antimicrobial Compounds Targeting Bacterial RNA Polymerase Complex Formation.
Alessia Caputo, Sara Sartini, Elisabetta Levati, Ilaria Minato, Gian Marco Elisi, Stéphane Bach

Antibiotics (Basel)· October 2022

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Structure Activity Relationship Studies around , a Potent and Selective Inhibitor of CLK Kinases.
Dabbugoddu Brahmaiah, Anagani Kanaka Durga Bhavani, Pasula Aparna, Nangunoori Sampath Kumar, Hélène Solhi, Stéphane Bach

Molecules· September 2022

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Nigratine as dual inhibitor of necroptosis and ferroptosis regulated cell death.
Claire Delehouzé, Arnaud Comte, Stephen Adonai Leon-Icaza, Céline Cougoule, Marcelle Hauteville, Stéphane Bach

Sci Rep· March 2022

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Synthesis and biological evaluation of selected 7H-pyrrolo[2,3-d]pyrimidine derivatives as novel CDK9/CyclinT and Haspin inhibitors.
Lianie Pieterse, Richard M Beteck, Blandine Baratte, Omobolanle J Jesumoroti, Thomas Robert, Stéphane Bach

Chem Biol Interact· November 2021

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Discovery of thiazolidin-4-one analogue as selective GSK-3β inhibitor through structure based virtual screening.
Bhanwar Singh Choudhary, Sukanya, Pakhuri Mehta, Stephane Bach, Sandrine Ruchaud

Bioorg Med Chem Lett· November 2021

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Dibenzofuran Derivatives Inspired from Cercosporamide as Dual Inhibitors of Pim and CLK1 Kinases.
Viet Hung Dao, Isabelle Ourliac-Garnier, Cédric Logé, Florence O McCarthy, Stéphane Bach

Molecules· October 2021

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Exploration of 7-azaindole-coumaranone hybrids and their analogues as protein kinase inhibitors.
Malikotsi A Qhobosheane, Richard M Beteck, Blandine Baratte, Thomas Robert, Sandrine Ruchaud, Stéphane Bach

Chem Biol Interact· July 2021

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Betulin, a Newly Characterized Compound in Bark, Is a Multi-Target Protein Kinase Inhibitor.
Augustine A Ahmadu, Claire Delehouzé, Anas Haruna, Lukman Mustapha, Bilqis A Lawal, Stéphane Bach

Molecules· July 2021

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New Quinoxaline Derivatives as Dual Pim-1/2 Kinase Inhibitors: Design, Synthesis and Biological Evaluation.
Bruno Oyallon, Marie Brachet-Botineau, Cédric Logé, Thomas Robert, Stéphane Bach

Molecules· February 2021

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