Publications by authors named "Stephane Demine"

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Pharmacological inhibition of tyrosine protein-kinase 2 reduces islet inflammation and delays type 1 diabetes onset in mice.
Farooq Syed, Olivia Ballew, Chih-Chun Lee, Jyoti Rana, Preethi Krishnan, Stephane Demine

EBioMedicine· July 2025

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PTPRK regulates glycolysis and de novo lipogenesis to promote hepatocyte metabolic reprogramming in obesity.
Eduardo H Gilglioni, Ao Li, Wadsen St-Pierre-Wijckmans, Tzu-Keng Shen, Israel Pérez-Chávez, Stéphane Demine

Nat Commun· November 2024

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Pharmacological inhibition of tyrosine protein-kinase 2 reduces islet inflammation and delays type 1 diabetes onset in mice.
Farooq Syed, Olivia Ballew, Chih-Chun Lee, Jyoti Rana, Preethi Krishnan, Stephane Demine

bioRxiv· May 2024

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HAMSAB diet ameliorates dysfunctional signaling in pancreatic islets in autoimmune diabetes.
Valerie Vandenbempt, Sema Elif Eski, Manoja K Brahma, Ao Li, Javier Negueruela, Stéphane Demine

iScience· January 2024

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Transcription and splicing regulation by NLRC5 shape the interferon response in human pancreatic β cells.
Florian Szymczak, Maria Inês Alvelos, Sandra Marín-Cañas, Ângela Castela, Stéphane Demine

Sci Adv· September 2022

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Nova1 or Bim Deficiency in Pancreatic β-Cells Does Not Alter Multiple Low-Dose Streptozotocin-Induced Diabetes and Diet-Induced Obesity in Mice.
Manoja K Brahma, Peng Xiao, Madalina Popa, Javier Negueruela, Valerie Vandenbempt, Stéphane Demine

Nutrients· September 2022

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Beta Cell Imaging-From Pre-Clinical Validation to First in Man Testing.
Stephane Demine, Michael L Schulte, Paul R Territo, Decio L Eizirik

Int J Mol Sci· October 2020

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A nanobody-based nuclear imaging tracer targeting dipeptidyl peptidase 6 to determine the mass of human beta cell grafts in mice.
Stéphane Demine, Rita Garcia Ribeiro, Julien Thevenet, Lorella Marselli, Piero Marchetti

Diabetologia· April 2020

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Pro-inflammatory cytokines induce cell death, inflammatory responses, and endoplasmic reticulum stress in human iPSC-derived beta cells.
Stéphane Demine, Andrea Alex Schiavo, Sandra Marín-Cañas, Piero Marchetti, Miriam Cnop

Stem Cell Res Ther· January 2020

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Mitochondrial Uncoupling: A Key Controller of Biological Processes in Physiology and Diseases.
Stéphane Demine, Patricia Renard, Thierry Arnould

Cells· July 2019

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Pancreatic β-cell tRNA hypomethylation and fragmentation link TRMT10A deficiency with diabetes.
Cristina Cosentino, Sanna Toivonen, Esteban Diaz Villamil, Mohamed Atta, Jean-Luc Ravanat, Stéphane Demine

Nucleic Acids Res· November 2018

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Imaging of Human Insulin Secreting Cells with Gd-DOTA-P88, a Paramagnetic Contrast Agent Targeting the Beta Cell Biomarker FXYD2γa.
Stéphane Demine, Alexander Balhuizen, Vinciane Debaille, Lieke Joosten, Maïté Fereau

Molecules· August 2018

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Mild mitochondrial uncoupling induces HSL/ATGL-independent lipolysis relying on a form of autophagy in 3T3-L1 adipocytes.
Stéphane Demine, Silvia Tejerina, Benoît Bihin, Marc Thiry, Nagabushana Reddy

J Cell Physiol· February 2018

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A nanobody-based tracer targeting DPP6 for non-invasive imaging of human pancreatic endocrine cells.
Alexander Balhuizen, Sam Massa, Iris Mathijs, Jean-Valery Turatsinze, Jens De Vos, Stéphane Demine

Sci Rep· November 2017

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Lipin-1 regulates cancer cell phenotype and is a potential target to potentiate rapamycin treatment.
Laura Brohée, Stéphane Demine, Jérome Willems, Thierry Arnould, Alain C Colige

Oncotarget· May 2015

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Unraveling biochemical pathways affected by mitochondrial dysfunctions using metabolomic approaches.
Stéphane Demine, Nagabushana Reddy, Patricia Renard, Martine Raes, Thierry Arnould

Metabolites· September 2014

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Different molecular mechanisms involved in spontaneous and oxidative stress-induced mitochondrial fragmentation in tripeptidyl peptidase-1 (TPP-1)-deficient fibroblasts.
Guillaume Van Beersel, Eliane Tihon, Stéphane Demine, Isabelle Hamer, Michel Jadot

Biosci Rep· February 2013

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Macroautophagy and cell responses related to mitochondrial dysfunction, lipid metabolism and unconventional secretion of proteins.
Stéphane Demine, Sébastien Michel, Kayleen Vannuvel, Anaïs Wanet, Patricia Renard

Cells· June 2012

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Mild mitochondrial uncoupling does not affect mitochondrial biogenesis but downregulates pyruvate carboxylase in adipocytes: role for triglyceride content reduction.
Aurélia De Pauw, Stéphane Demine, Silvia Tejerina, Marc Dieu, Edouard Delaive

Am J Physiol Endocrinol Metab· May 2012

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