Publications by authors named "Miriam Cnop"

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Declining FXR expression coordinates neonatal beta cell mass development with microbial bile acid metabolism maturation in mice.
Chenyang Fu, Tingting Li, Yiming Hao, Yiting Lin, Yixuan Qiu, Miriam Cnop

Diabetologia· December 2025

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Recessive TMEM167A variants cause neonatal diabetes, microcephaly, and epilepsy syndrome.
Enrico Virgilio, Sylvia Tielens, Georgia Bonfield, Fang-Shin Nian, Toshiaki Sawatani, Miriam Cnop

J Clin Invest· November 2025

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Identification of novel type 1 and type 2 diabetes genes by co-localization of human islet eQTL and GWAS variants with colocRedRibbon.
Anthony Piron, Florian Szymczak, Lise Folon, Daniel J M Crouch, Theodora Papadopoulou, Miriam Cnop

Cell Genom· November 2025

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Functional recovery of islet β cells in human type 2 diabetes: Transcriptome signatures unveil therapeutic approaches.
Mara Suleiman, Toshiaki Sawatani, Marta Tesi, Xiaoyan Yi, Theodora Papadopoulou, Miriam Cnop

Sci Adv· October 2025

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Diabetes mellitus and the key role of endoplasmic reticulum stress in pancreatic β cells.
Maria Lytrivi, Yue Tong, Enrico Virgilio, Xiaoyan Yi, Miriam Cnop

Nat Rev Endocrinol· September 2025

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Minimum effective low dose of antithymocyte globulin in people aged 5-25 years with recent-onset stage 3 type 1 diabetes (MELD-ATG): a phase 2, multicentre, double-blind, randomised, placebo-controlled, adaptive dose-ranging trial.
Chantal Mathieu, Julie Wych, A Emile J Hendriks, Lisa Van Ryckeghem, Timothy Tree, Miriam Cnop

Lancet· September 2025

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Exercise-induced meteorin-like protein protects human pancreatic beta cells from cytokine-induced apoptosis.
José Maria Costa-Junior, Alexandra Coomans de Brachène, Anyïshai E Musuaya, Priscila L Zimath, Eugenia Martin-Vazquez, Miriam Cnop

Diabetologia· July 2025

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Health-related fitness benefits following concurrent high-intensity interval training and resistance training in patients with type-1 diabetes or type-2 diabetes.
Corentin Scoubeau, Malgorzata Klass, Bert Celie, Chantal Godefroid, Miriam Cnop

Front Physiol· November 2024

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Functional genetics reveals the contribution of delta opioid receptor to type 2 diabetes and beta-cell function.
Sarah Meulebrouck, Judith Merrheim, Gurvan Queniat, Cyril Bourouh, Mehdi Derhourhi, Miriam Cnop

Nat Commun· August 2024

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Multi-omics characterization of type 2 diabetes associated genetic variation.
Ravi Mandla, Kim Lorenz, Xianyong Yin, Ozvan Bocher, Alicia Huerta-Chagoya, Miriam Cnop

medRxiv· July 2024

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Proinsulin folding and trafficking defects trigger a common pathological disturbance of endoplasmic reticulum homeostasis.
Anoop Arunagiri, Maroof Alam, Leena Haataja, Hassan Draz, Bashiyer Alasad, Miriam Cnop

Protein Sci· April 2024

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Impact of metformin and Dysosmobacter welbionis on diet-induced obesity and diabetes: from clinical observation to preclinical intervention.
Emilie Moens de Hase, Audrey M Neyrinck, Julie Rodriguez, Miriam Cnop, Nicolas Paquot

Diabetologia· February 2024

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RedRibbon: A new rank-rank hypergeometric overlap for gene and transcript expression signatures.
Anthony Piron, Florian Szymczak, Theodora Papadopoulou, Maria Inês Alvelos, Matthieu Defrance, Miriam Cnop

Life Sci Alliance· February 2024

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EndoC-βH5 cells are storable and ready-to-use human pancreatic beta cells with physiological insulin secretion.
Bruno Blanchi, Marion Taurand, Claire Colace, Sofia Thomaidou, Charlotte Audeoud, Miriam Cnop

Mol Metab· October 2023

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Impact of saturated compared with unsaturated dietary fat on insulin sensitivity, pancreatic β-cell function and glucose tolerance: a systematic review and meta-analysis of randomized, controlled trials.
Maria Lytrivi, Carolina Gomes Da Silveira Cauduro, Jésabelle Kibanda, Paulus Kristanto, Marianne Paesmans, Miriam Cnop

Am J Clin Nutr· October 2023

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LncRNA ARGI Contributes to Virus-Induced Pancreatic β Cell Inflammation Through Transcriptional Activation of IFN-Stimulated Genes.
Itziar González-Moro, Koldo Garcia-Etxebarria, Luis Manuel Mendoza, Nora Fernández-Jiménez, Jon Mentxaka, Miriam Cnop

Adv Sci (Weinh)· September 2023

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Inferring regulators of cell identity in the human adult pancreas.
Lotte Vanheer, Federica Fantuzzi, San Kit To, Andrea Schiavo, Matthias Van Haele, Miriam Cnop

NAR Genom Bioinform· September 2023

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Inhibition of the type 1 diabetes candidate gene PTPN2 aggravates TNF-α-induced human beta cell dysfunction and death.
Arturo Roca-Rivada, Sandra Marín-Cañas, Maikel L Colli, Chiara Vinci, Toshiaki Sawatani, Miriam Cnop

Diabetologia· August 2023

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A machine learning-based classification of adult-onset diabetes identifies patients at risk of liver-related complications.
Lukas Otero Sanchez, Clara-Yongxiang Zhan, Carolina Gomes da Silveira Cauduro, Laurent Crenier, Hassane Njimi, Miriam Cnop

JHEP Rep· August 2023

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GLP-1R agonists demonstrate potential to treat Wolfram syndrome in human preclinical models.
Vyron Gorgogietas, Bahareh Rajaei, Chae Heeyoung, Bruno J Santacreu, Sandra Marín-Cañas, Miriam Cnop

Diabetologia· July 2023

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The power of TOPMed imputation for the discovery of Latino-enriched rare variants associated with type 2 diabetes.
Alicia Huerta-Chagoya, Philip Schroeder, Ravi Mandla, Aaron J Deutsch, Wanying Zhu, Miriam Cnop

Diabetologia· July 2023

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Exercise as a non-pharmacological intervention to protect pancreatic beta cells in individuals with type 1 and type 2 diabetes.
Alexandra Coomans de Brachène, Corentin Scoubeau, Anyïshai E Musuaya, Jose Maria Costa-Junior, Angela Castela, Miriam Cnop

Diabetologia· March 2023

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A long non-coding RNA that harbors a SNP associated with type 2 diabetes regulates the expression of gene in pancreatic beta cells.
Itziar González-Moro, Henar Rojas-Márquez, Maialen Sebastian-delaCruz, Jon Mentxaka-Salgado, Ane Olazagoitia-Garmendia, Miriam Cnop

Front Endocrinol (Lausanne)· February 2023

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Sphingolipid subtypes differentially control proinsulin processing and systemic glucose homeostasis.
Kerstin Griess, Michael Rieck, Nadine Müller, Gergely Karsai, Sonja Hartwig, Miriam Cnop

Nat Cell Biol· January 2023

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A single-cell human islet interactome atlas identifies disrupted autocrine and paracrine communications in type 2 diabetes.
Emanuele Bosi, Lorella Marselli, Mara Suleiman, Marta Tesi, Carmela De Luca, Miriam Cnop

NAR Genom Bioinform· December 2022

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