Publications by authors named "Stephen B Long"

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Structure of the human TWIK-2 potassium channel and its inhibition by pimozide.
Nandish K Khanra, Chongyuan Wang, Bryce D Delgado, Stephen B Long

Proc Natl Acad Sci U S A· May 2025

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The pentameric chloride channel BEST1 is activated by extracellular GABA.
Swati Pant, Stephanie W Tam, Stephen B Long

Proc Natl Acad Sci U S A· April 2025

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Structure of the human TWIK-2 potassium channel and its inhibition by pimozide.
Nandish K Khanra, Chongyuan Wang, Bryce D Delgado, Stephen B Long

bioRxiv· February 2025

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The pentameric chloride channel BEST1 is activated by extracellular GABA.
Swati Pant, Stephanie W Tam, Stephen B Long

bioRxiv· November 2024

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Mechanisms of ion selectivity and throughput in the mitochondrial calcium uniporter.
Bryce D Delgado, Stephen B Long

Sci Adv· December 2022

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Gating choreography and mechanism of the human proton-activated chloride channel ASOR.
Chongyuan Wang, Maya M Polovitskaya, Bryce D Delgado, Thomas J Jentsch, Stephen B Long

Sci Adv· February 2022

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Substrate and product complexes reveal mechanisms of Hedgehog acylation by HHAT.
Yiyang Jiang, Thomas L Benz, Stephen B Long

Science· June 2021

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Cryo-EM structure of the calcium release-activated calcium channel Orai in an open conformation.
Xiaowei Hou, Ian R Outhwaite, Leanne Pedi, Stephen Barstow Long

Elife· November 2020

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Structure and Reconstitution of an MCU-EMRE Mitochondrial Ca Uniporter Complex.
Chongyuan Wang, Rozbeh Baradaran, Stephen Barstow Long

J Mol Biol· September 2020

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Structures reveal gatekeeping of the mitochondrial Ca uniporter by MICU1-MICU2.
Chongyuan Wang, Agata Jacewicz, Bryce D Delgado, Rozbeh Baradaran, Stephen Barstow Long

Elife· July 2020

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Molecular mechanisms of gating in the calcium-activated chloride channel bestrophin.
Alexandria N Miller, George Vaisey, Stephen B Long

Elife· January 2019

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An allosteric mechanism of inactivation in the calcium-dependent chloride channel BEST1.
George Vaisey, Stephen B Long

J Gen Physiol· November 2018

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Structures reveal opening of the store-operated calcium channel Orai.
Xiaowei Hou, Shana R Burstein, Stephen Barstow Long

Elife· August 2018

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Cryo-EM structures of fungal and metazoan mitochondrial calcium uniporters.
Rozbeh Baradaran, Chongyuan Wang, Andrew Francis Siliciano, Stephen Barstow Long

Nature· July 2018

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Atomic structure of the eukaryotic intramembrane RAS methyltransferase ICMT.
Melinda M Diver, Leanne Pedi, Akiko Koide, Shohei Koide, Stephen B Long

Nature· January 2018

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Distinct regions that control ion selectivity and calcium-dependent activation in the bestrophin ion channel.
George Vaisey, Alexandria N Miller, Stephen B Long

Proc Natl Acad Sci U S A· November 2016

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Structure and insights into the function of a Ca(2+)-activated Cl(-) channel.
Veronica Kane Dickson, Leanne Pedi, Stephen B Long

Nature· December 2014

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Mutational analysis of the integral membrane methyltransferase isoprenylcysteine carboxyl methyltransferase (ICMT) reveals potential substrate binding sites.
Melinda M Diver, Stephen B Long

J Biol Chem· September 2014

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Crystal structure of the calcium release-activated calcium channel Orai.
Xiaowei Hou, Leanne Pedi, Melinda M Diver, Stephen B Long

Science· December 2012

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Crystal structure of the human two-pore domain potassium channel K2P1.
Alexandria N Miller, Stephen B Long

Science· January 2012

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Merlin/NF2 functions upstream of the nuclear E3 ubiquitin ligase CRL4DCAF1 to suppress oncogenic gene expression.
Jonathan Cooper, Wei Li, Liru You, Gaia Schiavon, Angela Pepe-Caprio, Stephen B Long

Sci Signal· August 2011

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Merlin/NF2 suppresses tumorigenesis by inhibiting the E3 ubiquitin ligase CRL4(DCAF1) in the nucleus.
Wei Li, Liru You, Jonathan Cooper, Gaia Schiavon, Angela Pepe-Caprio, Stephen B Long

Cell· February 2010

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Crystal structure of an RNA aptamer bound to thrombin.
Stephen B Long, Meredith B Long, Rebekah R White, Bruce A Sullenger

RNA· December 2008

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Atomic structure of a voltage-dependent K+ channel in a lipid membrane-like environment.
Stephen B Long, Xiao Tao, Ernest B Campbell, Roderick MacKinnon

Nature· November 2007

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Crystal structure of a mammalian voltage-dependent Shaker family K+ channel.
Stephen B Long, Ernest B Campbell, Roderick Mackinnon

Science· August 2005

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