Publications by authors named "Stephen Methot"

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A scheduler for rhythmic gene expression.
Dimos Gaidatzis, Maike Graf-Landua, Stephen P Methot, Michaela Wölk, Giovanna Brancati

Mol Syst Biol· December 2025

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Addendum: Protein arginine methyltransferase 1 regulates B cell fate after positive selection in the germinal center in mice.
Ludivine C Litzler, Astrid Zahn, Kiersten L Dionne, Adrien Sprumont, Silvana R Ferreira, Stephen P Methot

J Exp Med· December 2025

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A scheduler for rhythmic gene expression.
Dimos Gaidatzis, Maike Graf-Landua, Stephen P Methot, Michaela Wölk, Giovanna Brancati

bioRxiv· September 2025

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Protein arginine methyltransferase 1 regulates B cell fate after positive selection in the germinal center in mice.
Ludivine C Litzler, Astrid Zahn, Kiersten L Dionne, Adrien Sprumont, Silvana R Ferreira, Stephen P Methot

J Exp Med· September 2023

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Establishment of H3K9-methylated heterochromatin and its functions in tissue differentiation and maintenance.
Jan Padeken, Stephen P Methot, Susan M Gasser

Nat Rev Mol Cell Biol· September 2022

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Author Correction: SETDB1-like MET-2 promotes transcriptional silencing and development independently of its H3K9me-associated catalytic activity.
Colin E Delaney, Stephen P Methot, Veronique Kalck, Jan Seebacher, Daniel Hess

Nat Struct Mol Biol· May 2022

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SETDB1-like MET-2 promotes transcriptional silencing and development independently of its H3K9me-associated catalytic activity.
Colin E Delaney, Stephen P Methot, Veronique Kalck, Jan Seebacher, Daniel Hess

Nat Struct Mol Biol· February 2022

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H3K9me selectively blocks transcription factor activity and ensures differentiated tissue integrity.
Stephen P Methot, Jan Padeken, Giovanna Brancati, Peter Zeller, Colin E Delaney

Nat Cell Biol· November 2021

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AID overexpression leads to aggressive murine CLL and nonimmunoglobulin mutations that mirror human neoplasms.
Pablo Elías Morande, Xiao-Jie Yan, Julieta Sepulveda, Noé Seija, María Elena Marquez, Stephen P Methot

Blood· July 2021

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Argonaute NRDE-3 and MBT domain protein LIN-61 redundantly recruit an H3K9me3 HMT to prevent embryonic lethality and transposon expression.
Jan Padeken, Stephen Methot, Peter Zeller, Colin E Delaney, Veronique Kalck

Genes Dev· January 2021

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Synergistic lethality between BRCA1 and H3K9me2 loss reflects satellite derepression.
Jan Padeken, Peter Zeller, Benjamin Towbin, Iskra Katic, Veronique Kalck, Stephen P Methot

Genes Dev· April 2019

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Heterochromatic foci and transcriptional repression by an unstructured MET-2/SETDB1 co-factor LIN-65.
Colin E Delaney, Stephen P Methot, Micol Guidi, Iskra Katic, Susan M Gasser

J Cell Biol· March 2019

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PRMT5 is essential for B cell development and germinal center dynamics.
Ludivine C Litzler, Astrid Zahn, Alexandre P Meli, Steven Hébert, Anne-Marie Patenaude, Stephen P Methot

Nat Commun· January 2019

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A licensing step links AID to transcription elongation for mutagenesis in B cells.
Stephen P Methot, Ludivine C Litzler, Poorani Ganesh Subramani, Anil K Eranki, Heather Fifield

Nat Commun· March 2018

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Pharmacological manipulation of AID.
Stephen P Methot, Javier M Di Noia

Oncotarget· September 2015

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Consecutive interactions with HSP90 and eEF1A underlie a functional maturation and storage pathway of AID in the cytoplasm.
Stephen P Methot, Ludivine C Litzler, Felipe Trajtenberg, Astrid Zahn, Francis Robert

J Exp Med· April 2015

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Targeting the tumour vasculature: exploitation of low oxygenation and sensitivity to NOS inhibition by treatment with a hypoxic cytotoxin.
Jennifer H E Baker, Alastair H Kyle, Kirsten L Bartels, Stephen P Methot, Erin J Flanagan

PLoS One· August 2014

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Activation induced deaminase C-terminal domain links DNA breaks to end protection and repair during class switch recombination.
Astrid Zahn, Anil K Eranki, Anne-Marie Patenaude, Stephen P Methot, Heather Fifield

Proc Natl Acad Sci U S A· March 2014

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A combined nuclear and nucleolar localization motif in activation-induced cytidine deaminase (AID) controls immunoglobulin class switching.
Yi Hu, Ida Ericsson, Kathrin Torseth, Stephen P Methot, Ottar Sundheim

J Mol Biol· January 2013

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Optimal functional levels of activation-induced deaminase specifically require the Hsp40 DnaJa1.
Alexandre Orthwein, Astrid Zahn, Stephen P Methot, David Godin, Silvestro G Conticello

EMBO J· February 2012

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Guanine-rich RNAs and DNAs that bind heme robustly catalyze oxygen transfer reactions.
Lester C-H Poon, Stephen P Methot, William Morabi-Pazooki, Frédéric Pio, Andrew J Bennet

J Am Chem Soc· February 2011

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