Publications by authors named "Stephen Tucker"

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Cryo-EM structure of the human THIK-1 K2P K channel reveals a lower Y gate regulated by lipids and anesthetics.
Karin E J Rödström, Bisher Eymsh, Peter Proks, Mehtab S Hayre, Sönke Cordeiro, Stephen J Tucker

Nat Struct Mol Biol· July 2025

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Structures of TASK-1 and TASK-3 K2P channels provide insight into their gating and dysfunction in disease.
Peter Rory Hall, Thibault Jouen-Tachoire, Marcus Schewe, Peter Proks, Thomas Baukrowitz, Stephen J Tucker

Structure· January 2025

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Electronic Polarizability Tunes the Function of the Human Bestrophin 1 Cl Channel.
Linda X Phan, Aaron P Owji, Tingting Yang, Jason Crain, Mark S P Sansom, Stephen J Tucker

J Chem Theory Comput· January 2025

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NIRS-BIDS: Brain Imaging Data Structure Extended to Near-Infrared Spectroscopy.
Robert Luke, Robert Oostenveld, Helena Cockx, Guiomar Niso, Maureen J Shader, Stephen Tucker

Sci Data· January 2025

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Electronic Polarizability Tunes the Function of the Human Bestrophin 1 Cl Channel.
Linda X Phan, Aaron P Owji, Tingting Yang, Jason Crain, Mark S P Sansom, Stephen J Tucker

bioRxiv· August 2024

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Extracellular modulation of TREK-2 activity with nanobodies provides insight into the mechanisms of K2P channel regulation.
Karin E J Rödström, Alexander Cloake, Janina Sörmann, Agnese Baronina, Kathryn H M Smith, Stephen J Tucker

Nat Commun· May 2024

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Temporal changes in toe-brachial index results in haemodialysis patients.
Belinda L Baines, Timothy Pianta, Mark Tacey, Cassandra Bramston, Matthew Cotchett, Stephen Tucker

PLoS One· April 2024

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ATI-1777, a Topical Jak1/3 Inhibitor, May Benefit Atopic Dermatitis without Systemic Drug Exposure: Results from Preclinical Development and Phase 2a Randomized Control Study ATI-1777-AD-201.
Paul Changelian, Canxin Xu, Steve Mnich, Heidi Hope, Kourtney Kostecki, Stephen Tucker

JID Innov· March 2024

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Transcending Markov: non-Markovian rate processes of thermosensitive TRP ion channels.
Yuval Ben-Abu, Stephen J Tucker, Sonia Contera

R Soc Open Sci· August 2023

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Limitations of non-polarizable force fields in describing anion binding poses in non-polar synthetic hosts.
David Seiferth, Stephen J Tucker, Philip C Biggin

Phys Chem Chem Phys· July 2023

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Optical coherence tomography-based design for a real-time motion corrected scanning microscope.
Stephen S Tucker, John T Giblin, Kivilcim Kiliç, Anderson Chen, Jianbo Tang

Opt Lett· July 2023

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Correction: Limitations of non-polarizable force fields in describing anion binding poses in non-polar synthetic hosts.
David Seiferth, Stephen J Tucker, Philip C Biggin

Phys Chem Chem Phys· July 2023

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Influence of electronic polarization on the binding of anions to a chloride-pumping rhodopsin.
Linda X Phan, Victor Cruces Chamorro, Hector Martinez-Seara, Jason Crain, Mark S P Sansom, Stephen J Tucker

Biophys J· April 2023

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Introduction to the shared near infrared spectroscopy format.
Stephen Tucker, Jay Dubb, Sreekanth Kura, Alexander von Lühmann, Robert Franke

Neurophotonics· January 2023

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When is a hydrophobic gate not a hydrophobic gate?
David Seiferth, Philip C Biggin, Stephen J Tucker

J Gen Physiol· November 2022

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Gain-of-function mutations in KCNK3 cause a developmental disorder with sleep apnea.
Janina Sörmann, Marcus Schewe, Peter Proks, Thibault Jouen-Tachoire, Shanlin Rao, Stephen J Tucker

Nat Genet· October 2022

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Structural basis for proton coupled cystine transport by cystinosin.
Mark Löbel, Sacha P Salphati, Kamel El Omari, Armin Wagner, Stephen J Tucker

Nat Commun· August 2022

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Influence of effective polarization on ion and water interactions within a biomimetic nanopore.
Linda X Phan, Charlotte I Lynch, Jason Crain, Mark S P Sansom, Stephen J Tucker

Biophys J· June 2022

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Transition between conformational states of the TREK-1 K2P channel promoted by interaction with PIP.
Adisorn Panasawatwong, Tanadet Pipatpolkai, Stephen J Tucker

Biophys J· June 2022

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Water Nanoconfined in a Hydrophobic Pore: Molecular Dynamics Simulations of Transmembrane Protein 175 and the Influence of Water Models.
Charlotte I Lynch, Gianni Klesse, Shanlin Rao, Stephen J Tucker, Mark S P Sansom

ACS Nano· December 2021

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Effects of ionic strength on gating and permeation of TREK-2 K2P channels.
Linus J Conrad, Peter Proks, Stephen J Tucker

PLoS One· November 2021

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Norfluoxetine inhibits TREK-2 K2P channels by multiple mechanisms including state-independent effects on the selectivity filter gate.
Peter Proks, Marcus Schewe, Linus J Conrad, Shanlin Rao, Kristin Rathje, Stephen J Tucker

J Gen Physiol· August 2021

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Ion channels as convergence points in the pathology of pulmonary arterial hypertension.
Thibault R H Jouen-Tachoire, Stephen J Tucker, Paolo Tammaro

Biochem Soc Trans· August 2021

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Biallelic Variants Associated with Intellectual Disability and Neurodevelopmental Disorders Alter TRESK Channel Activity.
Lisa Pavinato, Ehsan Nematian-Ardestani, Andrea Zonta, Silvia De Rubeis, Joseph Buxbaum, Stephen J Tucker

Int J Mol Sci· June 2021

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(Kir5.1) Gene Ablation Causes Subfertility and Increases the Prevalence of Morphologically Abnormal Spermatozoa.
Giulia Poli, Sonia Hasan, Silvia Belia, Marta Cenciarini, Stephen J Tucker

Int J Mol Sci· June 2021

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