Publications by authors named "Stephin Vervoort"

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CRISPR screens define unified hallmarks of cancer cell-autonomous immune evasion.
Anne Huber, Tirta M Djajawi, Isela Sarahi Rivera, Stephin J Vervoort, Conor J Kearney

Cell Rep· December 2025

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A TAK1 cytokine toxicity checkpoint controls anti-cancer immunity.
Tirta M Djajawi, Anne Huber, Sarahi Mendoza Rivera, Akash Srivaths, Maede Salehi, Stephin J Vervoort

Cell Rep· December 2025

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Protocol for double-crosslinking ChIP-seq to improve data quality and enhance detection of challenging chromatin targets.
Yu Bao, Roberta Cacioppo, Alastair Crisp, Ivan Shlamovitz, Julian E Sale, Stephin J Vervoort

STAR Protoc· October 2025

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A CDK11-dependent RNA polymerase II pause-checkpoint precedes CDK9-mediated transition to transcriptional elongation.
Jennifer R Devlin, Ben Martin, Nenad Bartonicek, Keziah Ting, Zheng Fan, Stephin J Vervoort

Mol Cell· September 2025

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MORC2 is a phosphorylation-dependent DNA compaction machine.
Winnie Tan, Jeongveen Park, Hariprasad Venugopal, Jieqiong Lou, Prabavi Shayana Dias, Stephin J Vervoort

Nat Commun· July 2025

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Lipid-metabolism-focused CRISPR screens identify enzymes of the mevalonate pathway as essential for prostate cancer growth.
Gio Fidelito, Izabela Todorovski, Leonie Cluse, Stephin J Vervoort, Renea A Taylor

Cell Rep· April 2025

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Intracellular zinc protects tumours from T cell-mediated cytotoxicity.
Emily J Lelliott, Jonathan Naddaf, Katherine Ganio, Jessica Michie, Shelly Wang, Stephin J Vervoort

Cell Death Differ· December 2024

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RNA kinetics influence the response to transcriptional perturbation in leukaemia cell lines.
Izabela Todorovski, Mary-Jane Tsang, Breon Feran, Zheng Fan, Sreeja Gadipally, Stephin J Vervoort

NAR Cancer· December 2024

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Mapping the IMiD-dependent cereblon interactome using BioID-proximity labelling.
Matteo Costacurta, Jarrod J Sandow, Belinda Maher, Olivia Susanto, Stephin J Vervoort

FEBS J· November 2024

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MORC2 phosphorylation fine tunes its DNA compaction activity.
Winnie Tan, Jeong Veen Park, Hariprasad Venugopal, Jie Qiong Lou, Prabavi Shayana Dias, Stephin J Vervoort

bioRxiv· June 2024

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Tumor immune evasion: insights from CRISPR screens and future directions.
Tirta Mario Djajawi, Johannes Wichmann, Stephin J Vervoort, Conor J Kearney

FEBS J· April 2024

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PRMT1 acts as a suppressor of MHC-I and anti-tumor immunity.
Tirta M Djajawi, Lizzy Pijpers, Akash Srivaths, David Chisanga, Kok Fei Chan, Stephin J Vervoort

Cell Rep· March 2024

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CRISPR-Cas9 screening identifies an IRF1-SOCS1-mediated negative feedback loop that limits CXCL9 expression and antitumor immunity.
Imran G House, Emily B Derrick, Kevin Sek, Amanda X Y Chen, Jasmine Li, Stephin J Vervoort

Cell Rep· February 2024

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Epigenetic changes in inflammatory arthritis monocytes contribute to disease and can be targeted by JAK inhibition.
Janneke G C Peeters, Arjan Boltjes, Rianne C Scholman, Stephin J Vervoort, Paul J Coffer

Rheumatology (Oxford)· August 2023

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CRISPR-Cas9 screening identifies an IRF1-SOCS1-mediated negative feedback loop that limits CXCL9 expression and antitumor immunity.
Imran G House, Emily B Derrick, Kevin Sek, Amanda X Y Chen, Jasmine Li, Stephin J Vervoort

Cell Rep· August 2023

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Epigenetic modulators of B cell fate identified through coupled phenotype-transcriptome analysis.
Isabella Y Kong, Stephanie Trezise, Amanda Light, Izabela Todorovski, Gisela Mir Arnau, Stephin J Vervoort

Cell Death Differ· December 2022

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Inhibition of pyrimidine biosynthesis targets protein translation in acute myeloid leukemia.
Joan So, Alexander C Lewis, Lorey K Smith, Kym Stanley, Rheana Franich, Stephin J Vervoort

EMBO Mol Med· July 2022

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Distinct modulation of IFNγ-induced transcription by BET bromodomain and catalytic P300/CBP inhibition in breast cancer.
Simon J Hogg, Olga Motorna, Conor J Kearney, Emily B Derrick, Imran G House, Stephin J Vervoort

Clin Epigenetics· July 2022

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Epigenetic Activation of Plasmacytoid DCs Drives IFNAR-Dependent Therapeutic Differentiation of AML.
Jessica M Salmon, Izabela Todorovski, Kym L Stanley, Claudia Bruedigam, Conor J Kearney, Stephin J Vervoort

Cancer Discov· June 2022

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Integrated clinical and genomic evaluation of guadecitabine (SGI-110) in peripheral T-cell lymphoma.
Jonathan Wong, Emily Gruber, Belinda Maher, Mark Waltham, Zahra Sabouri-Thompson, Stephin Vervoort

Leukemia· June 2022

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Targeting transcription cycles in cancer.
Stephin J Vervoort, Jennifer R Devlin, Nicholas Kwiatkowski, Mingxing Teng, Nathanael S Gray

Nat Rev Cancer· January 2022

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BET Inhibition Enhances TNF-Mediated Antitumor Immunity.
Lisa C Wellinger, Simon J Hogg, Dane M Newman, Thomas Friess, Daniela Geiss, Stephin J Vervoort

Cancer Immunol Res· January 2022

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HOIP limits anti-tumor immunity by protecting against combined TNF and IFN-gamma-induced apoptosis.
Andrew J Freeman, Stephin J Vervoort, Jessica Michie, Kelly M Ramsbottom, John Silke

EMBO Rep· November 2021

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Loss of erythroblasts in acute myeloid leukemia causes iron redistribution with clinical implications.
Marta Lopes, Tiago L Duarte, Maria J Teles, Laura Mosteo, Sérgio Chacim, Stephin Vervoort

Blood Adv· August 2021

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Targeting histone acetylation dynamics and oncogenic transcription by catalytic P300/CBP inhibition.
Simon J Hogg, Olga Motorna, Leonie A Cluse, Timothy M Johanson, Hannah D Coughlan, Stephin J Vervoort

Mol Cell· May 2021

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