Publications by authors named "Steven A Howell"

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The yeast RNA methylation complex consists of conserved yet reconfigured components with m6A-dependent and independent roles.
Imke Ensinck, Alexander Maman, Waleed S Albihlal, Michelangelo Lassandro, Giulia Salzano, Steven A Howell

Elife· July 2023

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A malaria parasite phospholipase facilitates efficient asexual blood stage egress.
Abhinay Ramaprasad, Paul-Christian Burda, Konstantinos Koussis, James A Thomas, Emma Pietsch, Steven A Howell

PLoS Pathog· June 2023

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Autocatalytic activation of a malarial egress protease is druggable and requires a protein cofactor.
Michele S Y Tan, Konstantinos Koussis, Chrislaine Withers-Martinez, Steven A Howell, James A Thomas

EMBO J· June 2021

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Response to Comment on "Circadian rhythms in the absence of the clock gene ".
Sandipan Ray, Utham K Valekunja, Alessandra Stangherlin, Steven A Howell, Ambrosius P Snijders

Science· April 2021

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Response to Comment on "Circadian rhythms in the absence of the clock gene ".
Sandipan Ray, Utham K Valekunja, Alessandra Stangherlin, Steven A Howell, Ambrosius P Snijders

Science· April 2021

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Ca signals critical for egress and gametogenesis in malaria parasites depend on a multipass membrane protein that interacts with PKG.
Aurélia C Balestra, Konstantinos Koussis, Natacha Klages, Steven A Howell, Helen R Flynn

Sci Adv· March 2021

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The malaria parasite sheddase SUB2 governs host red blood cell membrane sealing at invasion.
Christine R Collins, Fiona Hackett, Steven A Howell, Ambrosius P Snijders, Matthew Rg Russell

Elife· December 2020

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Depleted circulatory complement-lysis inhibitor (CLI) in childhood cerebral malaria returns to normal with convalescence.
Samuel Eneọjọ Abah, Florence Burté, Steven A Howell, Ikeoluwa Lagunju, Wuraola A Shokunbi

Malar J· April 2020

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Circadian rhythms in the absence of the clock gene .
Sandipan Ray, Utham K Valekunja, Alessandra Stangherlin, Steven A Howell, Ambrosius P Snijders

Science· February 2020

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Divergent roles for the RH5 complex components, CyRPA and RIPR in human-infective malaria parasites.
Ellen Knuepfer, Katherine E Wright, Surendra Kumar Prajapati, Thomas A Rawlinson, Franziska Mohring, Steven A Howell

PLoS Pathog· June 2019

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Compositional and expression analyses of the glideosome during the life cycle reveal an additional myosin light chain required for maximum motility.
Judith L Green, Richard J Wall, Juha Vahokoski, Noor A Yusuf, Mohd A Mohd Ridzuan, Steven A Howell

J Biol Chem· October 2017

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The Binding of Plasmodium falciparum Adhesins and Erythrocyte Invasion Proteins to Aldolase Is Enhanced by Phosphorylation.
Suraya A Diaz, Stephen R Martin, Steven A Howell, Munira Grainger, Robert W Moon

PLoS One· August 2017

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Imidazopyridazine Inhibitors of Plasmodium falciparum Calcium-Dependent Protein Kinase 1 Also Target Cyclic GMP-Dependent Protein Kinase and Heat Shock Protein 90 To Kill the Parasite at Different Stages of Intracellular Development.
Judith L Green, Robert W Moon, David Whalley, Paul W Bowyer, Claire Wallace, Steven A Howell

Antimicrob Agents Chemother· December 2015

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Phospho-dependent Regulation of SAMHD1 Oligomerisation Couples Catalysis and Restriction.
Laurence H Arnold, Harriet C T Groom, Simone Kunzelmann, David Schwefel, Sarah J Caswell, Steven A Howell

PLoS Pathog· October 2015

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The Plasmodium Class XIV Myosin, MyoB, Has a Distinct Subcellular Location in Invasive and Motile Stages of the Malaria Parasite and an Unusual Light Chain.
Noor A Yusuf, Judith L Green, Richard J Wall, Ellen Knuepfer, Robert W Moon, Steven A Howell

J Biol Chem· May 2015

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Plasmodium falciparum SERA5 plays a non-enzymatic role in the malarial asexual blood-stage lifecycle.
Robert Stallmach, Manoli Kavishwar, Chrislaine Withers-Martinez, Fiona Hackett, Christine R Collins, Steven A Howell

Mol Microbiol· April 2015

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Plasmodium falciparum aldolase and the C-terminal cytoplasmic domain of certain apical organellar proteins promote actin polymerization.
Suraya A Diaz, Stephen R Martin, Munira Grainger, Steven A Howell, Judith L Green

Mol Biochem Parasitol· October 2014

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The malaria parasite egress protease SUB1 is a calcium-dependent redox switch subtilisin.
Chrislaine Withers-Martinez, Malcolm Strath, Fiona Hackett, Lesley F Haire, Steven A Howell

Nat Commun· May 2014

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Structure of mammalian AMPK and its regulation by ADP.
Bing Xiao, Matthew J Sanders, Elizabeth Underwood, Richard Heath, Faith V Mayer, Steven A Howell

Nature· April 2011

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Targeted disruption of py235ebp-1: invasion of erythrocytes by Plasmodium yoelii using an alternative Py235 erythrocyte binding protein.
Solabomi A Ogun, Rita Tewari, Thomas D Otto, Steven A Howell, Ellen Knuepfer

PLoS Pathog· February 2011

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Phosphorylation of the human papillomavirus type 16 E1--E4 protein at T57 by ERK triggers a structural change that enhances keratin binding and protein stability.
Qian Wang, Alan Kennedy, Papia Das, Pauline B McIntosh, Steven A Howell

J Virol· April 2009

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Malarial EBA-175 region VI crystallographic structure reveals a KIX-like binding interface.
Chrislaine Withers-Martinez, Lesley F Haire, Fiona Hackett, Philip A Walker, Steven A Howell

J Mol Biol· January 2008

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Intramembrane proteolysis mediates shedding of a key adhesin during erythrocyte invasion by the malaria parasite.
Rebecca A O'Donnell, Fiona Hackett, Steven A Howell, Moritz Treeck, Nicole Struck

J Cell Biol· September 2006

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A member of the py235 gene family of Plasmodium yoelii encodes an erythrocyte binding protein recognised by a protective monoclonal antibody.
Solabomi A Ogun, Steven A Howell, Helen M Taylor, Anthony A Holder

Mol Biochem Parasitol· May 2006

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Distinct mechanisms govern proteolytic shedding of a key invasion protein in apicomplexan pathogens.
Steven A Howell, Fiona Hackett, Artemio M Jongco, Chrislaine Withers-Martinez, Kami Kim

Mol Microbiol· September 2005

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