Publications by authors named "Steven A Short"

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The human ACC2 CT-domain C-terminus is required for full functionality and has a novel twist.
Kevin P Madauss, William A Burkhart, Thomas G Consler, David J Cowan, William K Gottschalk, Steven A Short

Acta Crystallogr D Biol Crystallogr· May 2009

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Structural basis for the improved drug resistance profile of new generation benzophenone non-nucleoside HIV-1 reverse transcriptase inhibitors.
Jingshan Ren, Philip P Chamberlain, Anna Stamp, Steven A Short, Kurt L Weaver

J Med Chem· August 2008

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Relationship of potency and resilience to drug resistant mutations for GW420867X revealed by crystal structures of inhibitor complexes for wild-type, Leu100Ile, Lys101Glu, and Tyr188Cys mutant HIV-1 reverse transcriptases.
Jingshan Ren, Charles E Nichols, Philip P Chamberlain, Kurt L Weaver, Steven A Short

J Med Chem· May 2007

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Structural insights into mechanisms of non-nucleoside drug resistance for HIV-1 reverse transcriptases mutated at codons 101 or 138.
Jingshan Ren, Charles E Nichols, Anna Stamp, Phillip P Chamberlain, Robert Ferris, Steven A Short

FEBS J· August 2006

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Structure-activity relationship studies of novel benzophenones leading to the discovery of a potent, next generation HIV nonnucleoside reverse transcriptase inhibitor.
Karen R Romines, George A Freeman, Lee T Schaller, Jill R Cowan, Steve S Gonzales, Steven A Short

J Med Chem· January 2006

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Anti-human immunodeficiency virus type 1 activity of the nonnucleoside reverse transcriptase inhibitor GW678248 in combination with other antiretrovirals against clinical isolate viruses and in vitro selection for resistance.
Richard J Hazen, Robert J Harvey, Marty H St Clair, Robert G Ferris, George A Freeman, Steven A Short

Antimicrob Agents Chemother· November 2005

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Antiviral activity of GW678248, a novel benzophenone nonnucleoside reverse transcriptase inhibitor.
Robert G Ferris, Richard J Hazen, Grace B Roberts, Marty H St Clair, Joseph H Chan, Steven A Short

Antimicrob Agents Chemother· October 2005

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Design of non-nucleoside inhibitors of HIV-1 reverse transcriptase with improved drug resistance properties. 2.
George A Freeman, C Webster Andrews Iii, Andrew L Hopkins, Gina S Lowell, Lee T Schaller, Steven A Short

J Med Chem· November 2004

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Fourier transform ion cyclotron resonance MS reveals the presence of a water molecule in an enzyme transition-state analogue complex.
Christoph H Borchers, Victor E Marquez, Gottfried K Schroeder, Steven A Short, Mark J Snider

Proc Natl Acad Sci U S A· October 2004

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Progesterone receptor ligand binding pocket flexibility: crystal structures of the norethindrone and mometasone furoate complexes.
Kevin P Madauss, Su-Jun Deng, Robert J H Austin, Millard H Lambert, Iain McLay, Steven A Short

J Med Chem· June 2004

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Novel benzophenones as non-nucleoside reverse transcriptase inhibitors of HIV-1.
Joseph H Chan, George A Freeman, Jeffrey H Tidwell, Karen R Romines, Lee T Schaller, Steven A Short

J Med Chem· February 2004

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