Publications by authors named "Steven Bartz"

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DGAT2 Inhibition Alters Aspects of Triglyceride Metabolism in Rodents but Not in Non-human Primates.
David G McLaren, Seongah Han, Beth Ann Murphy, Larissa Wilsie, Steven J Stout, Steven R Bartz

Cell Metab· June 2018

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Dose-dependent effects of siRNA-mediated inhibition of SCAP on PCSK9, LDLR, and plasma lipids in mouse and rhesus monkey.
Kristian K Jensen, Marija Tadin-Strapps, Sheng-Ping Wang, James Hubert, Yanqing Kan, Steven Bartz

J Lipid Res· December 2016

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Alterations in the hepatic transcriptional landscape after RNAi mediated ApoB silencing in cynomolgus monkeys.
M Sabry Hamza, Chanchal Kumar, Ser Mien Chia, Vidhya Anandalakshmi, Nicole Boo, Steven Bartz

Atherosclerosis· October 2015

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Targeting of hepatic angiotensinogen using chemically modified siRNAs results in significant and sustained blood pressure lowering in a rat model of hypertension.
Jeffrey Olearczyk, Sheng Gao, Marianne Eybye, Satyasri Yendluri, Lori Andrews, Steven Bartz

Hypertens Res· May 2014

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A multiplexed siRNA screening strategy to identify genes in the PARP pathway.
Erica Stec, Louis Locco, Stacey Szymanski, Steven R Bartz, Carlo Toniatti

J Biomol Screen· December 2012

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Assessing unintended hybridization-induced biological effects of oligonucleotides.
Morten Lindow, Hans-Peter Vornlocher, Donald Riley, Douglas J Kornbrust, Julja Burchard, Steven Bartz

Nat Biotechnol· October 2012

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Attenuation of Slc27a5 gene expression followed by LC-MS measurement of bile acid reconjugation using metabolomics and a stable isotope tracer strategy.
Jose M Castro-Perez, Thomas P Roddy, Vinit Shah, Sheng-Ping Wang, Xuesong Ouyang, Steven R Bartz

J Proteome Res· October 2011

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Gene expression signature of c-MYC-immortalized human fibroblasts reveals loss of growth inhibitory response to TGFβ.
Myra L Wang, Ryan Walsh, Kristin L Robinson, Julja Burchard, Steven R Bartz

Cell Cycle· August 2011

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siRNA-induced liver ApoB knockdown lowers serum LDL-cholesterol in a mouse model with human-like serum lipids.
Marija Tadin-Strapps, Laurence B Peterson, Anne-Marie Cumiskey, Raymond L Rosa, Vivienne Halili Mendoza, Steven R Bartz

J Lipid Res· June 2011

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Improved efficacy for ezetimibe and rosuvastatin by attenuating the induction of PCSK9.
Brandon Ason, Samnang Tep, Harry R Davis, Yiming Xu, Glen Tetzloff, Steven R Bartz

J Lipid Res· April 2011

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The siRNA sequence and guide strand overhangs are determinants of in vivo duration of silencing.
Walter R Strapps, Victoria Pickering, Gladys T Muiru, Julie Rice, Stacey Orsborn, Steven R Bartz

Nucleic Acids Res· August 2010

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Chromosome 20q amplification regulates in vitro response to Kinesin-5 inhibitor.
Aimee L Jackson, Mao Mao, Sumire Kobayashi, Teresa Ward, Matthew Biery, Steven R Bartz

Cancer Inform· May 2010

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MicroRNA miR-210 modulates cellular response to hypoxia through the MYC antagonist MNT.
Zhan Zhang, Hong Sun, Hongyue Dai, Ryan M Walsh, Maki Imakura, Steven R Bartz

Cell Cycle· September 2009

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MicroRNA-like off-target transcript regulation by siRNAs is species specific.
Julja Burchard, Aimee L Jackson, Vladislav Malkov, Rachel H V Needham, Yejun Tan, Steven R Bartz

RNA· February 2009

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An efficient and fully automated high-throughput transfection method for genome-scale siRNA screens.
Namjin Chung, Louis Locco, Kevin W Huff, Steven Bartz, Peter S Linsley

J Biomol Screen· February 2008

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Median absolute deviation to improve hit selection for genome-scale RNAi screens.
Namjin Chung, Xiaohua Douglas Zhang, Anthony Kreamer, Louis Locco, Pei-Fen Kuan, Steven Bartz

J Biomol Screen· February 2008

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Hypoxia-inducible factor linked to differential kidney cancer risk seen with type 2A and type 2B VHL mutations.
Lianjie Li, Liang Zhang, Xiaoping Zhang, Qin Yan, Yoji Andrew Minamishima, Steven Bartz

Mol Cell Biol· August 2007

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The hypoxia-inducible factor 2alpha N-terminal and C-terminal transactivation domains cooperate to promote renal tumorigenesis in vivo.
Qin Yan, Steven Bartz, Mao Mao, Lianjie Li, William G Kaelin

Mol Cell Biol· March 2007

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Transcripts targeted by the microRNA-16 family cooperatively regulate cell cycle progression.
Peter S Linsley, Janell Schelter, Julja Burchard, Miho Kibukawa, Melissa M Martin, Steven R Bartz

Mol Cell Biol· March 2007

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Small interfering RNA screens reveal enhanced cisplatin cytotoxicity in tumor cells having both BRCA network and TP53 disruptions.
Steven R Bartz, Zhan Zhang, Julja Burchard, Maki Imakura, Melissa Martin

Mol Cell Biol· December 2006

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A genome wide analysis of ubiquitin ligases in APP processing identifies a novel regulator of BACE1 mRNA levels.
Amy S Espeseth, Qian Huang, Adam Gates, Min Xu, Yuanjiang Yu, Steven Bartz

Mol Cell Neurosci· November 2006

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LRRTM3 promotes processing of amyloid-precursor protein by BACE1 and is a positional candidate gene for late-onset Alzheimer's disease.
John Majercak, William J Ray, Amy Espeseth, Adam Simon, Xiao-Ping Shi, Steven Bartz

Proc Natl Acad Sci U S A· November 2006

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How will RNAi facilitate drug development?
Steven Bartz, Aimee L Jackson

Sci STKE· August 2005

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Expression profiling reveals off-target gene regulation by RNAi.
Aimee L Jackson, Steven R Bartz, Janell Schelter, Sumire V Kobayashi, Julja Burchard

Nat Biotechnol· June 2003

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HIV-1 Vpr does not inhibit CTL-mediated apoptosis of HIV-1 infected cells.
Deborah A Lewinsohn, Rebecca Lines, David M Lewinsohn, Stanley R Riddell, Philip D Greenberg, Steven R Bartz

Virology· March 2002

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