Publications by authors named "Steven Burakoff"

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A perspective on HPK1 as a novel immuno-oncology drug target.
Sansana Sawasdikosol, Steven Burakoff

Elife· September 2020

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HPK1 Influences Regulatory T Cell Functions.
Sansana Sawasdikosol, Renyuan Zha, Timothy S Fisher, Saba Alzabin, Steven J Burakoff

Immunohorizons· July 2020

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Multiple conformational states of the HPK1 kinase domain in complex with sunitinib reveal the structural changes accompanying HPK1 trans-regulation.
Eric Johnson, Michele McTigue, Rebecca A Gallego, Ted W Johnson, Sergei Timofeevski, Steven Burakoff

J Biol Chem· June 2019

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The Structure of HPK1 Kinase Domain: To Boldly Go Where No Immuno-Oncology Drugs Have Gone Before.
Sansana Sawasdikosol, Steven Burakoff

Structure· January 2019

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Dissection of immune gene networks in primary melanoma tumors critical for antitumor surveillance of patients with stage II-III resectable disease.
Shanthi Sivendran, Rui Chang, Lisa Pham, Robert G Phelps, Sara T Harcharik, Steven J Burakoff

J Invest Dermatol· August 2014

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Identification of a novel binding site between HIV type 1 Nef C-terminal flexible loop and AP2 required for Nef-mediated CD4 downregulation.
Yong-Jiu Jin, Catherine Yi Cai, Mihaly Mezei, Michael Ohlmeyer, Roberto Sanchez, Steven J Burakoff

AIDS Res Hum Retroviruses· April 2013

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HPK1 as a novel target for cancer immunotherapy.
Sansana Sawasdikosol, Renyuan Zha, Boyu Yang, Steven Burakoff

Immunol Res· December 2012

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A remembrance of Baruj Benacerraf (AAI '57) 1920-2011.
Ronald N Germain, Steven J Burakoff

J Immunol· December 2011

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CD43 regulates the threshold for T cell activation by targeting Cbl functions.
Gustavo Pedraza-Alva, Lilia B Mérida, Roxana del Rio, Nora A Fierro, Mario E Cruz-Muñoz, Steven J Burakoff

IUBMB Life· October 2011

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Non-invasive in vivo imaging for liver tumour progression using an orthotopic hepatocellular carcinoma model in immunocompetent mice.
Qin Wang, Wei Luan, Vadim Goz, Steven J Burakoff, Spiros P Hiotis

Liver Int· September 2011

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Cancer therapy from bench to bedside.
William K Oh, Steven J Burakoff

Mt Sinai J Med· June 2011

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Two sorting motifs, a ubiquitination motif and a tyrosine motif, are involved in HIV-1 and simian immunodeficiency virus Nef-mediated receptor endocytosis.
Catherine Yi Cai, Xiaoping Zhang, Patrick J Sinko, Steven J Burakoff, Yong-Jiu Jin

J Immunol· May 2011

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Alkylating HIV-1 Nef - a potential way of HIV intervention.
Yong-Jiu Jin, Xiaoping Zhang, Catherine Yi Cai, Steven J Burakoff

AIDS Res Ther· July 2010

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Hematopoietic progenitor kinase 1 is a critical component of prostaglandin E2-mediated suppression of the anti-tumor immune response.
Saba Alzabin, Saiju Pyarajan, Herman Yee, Friedemann Kiefer, Akira Suzuki, Steven Burakoff

Cancer Immunol Immunother· March 2010

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Hematopoietic progenitor kinase 1 is a negative regulator of dendritic cell activation.
Saba Alzabin, Nina Bhardwaj, Friedemann Kiefer, Sansana Sawasdikosol, Steven Burakoff

J Immunol· May 2009

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Interleukin-3 (IL-3)-induced c-fos activation is modulated by Gab2-calcineurin interaction.
Saiju Pyarajan, Gabriel Matejovic, Joanne C Pratt, Shairaz Baksh, Steven J Burakoff

J Biol Chem· August 2008

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Lysine 144, a ubiquitin attachment site in HIV-1 Nef, is required for Nef-mediated CD4 down-regulation.
Yong-Jiu Jin, Catherine Yi Cai, Xiaoping Zhang, Steven J Burakoff

J Immunol· June 2008

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Prostaglandin E2 activates HPK1 kinase activity via a PKA-dependent pathway.
Sansana Sawasdikosol, Saiju Pyarajan, Saba Alzabin, Gabriel Matejovic, Steven J Burakoff

J Biol Chem· November 2007

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From bytes to bedside: data integration and computational biology for translational cancer research.
Jomol P Mathew, Barry S Taylor, Gary D Bader, Saiju Pyarajan, Marco Antoniotti, Steven J Burakoff

PLoS Comput Biol· February 2007

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A CD8/Lck transgene is able to drive thymocyte differentiation.
Ruben C Fragoso, Saiju Pyarajan, Hanna Yoko Irie, Steven J Burakoff

J Immunol· November 2006

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Signaling T-cell survival and death by IL-2 and IL-15.
Elizabeth Zambricki, Alana Shigeoka, Hidehiro Kishimoto, Jon Sprent, Steven Burakoff

Am J Transplant· November 2005

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HIV Nef-mediated CD4 down-regulation is adaptor protein complex 2 dependent.
Yong-Jiu Jin, Catherine Yi Cai, Xiaoping Zhang, Hui-Tang Zhang, John A Hirst, Steven J Burakoff

J Immunol· September 2005

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Nicotine activates nuclear factor of activated T cells c2 (NFATc2) and prevents cell cycle entry in T cells.
Ashley A Frazer-Abel, Shairaz Baksh, Susan P Fosmire, Derall Willis, Angela M Pierce, Steven J Burakoff

J Pharmacol Exp Ther· November 2004

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CD4 phosphorylation partially reverses Nef down-regulation of CD4.
Yong-Jiu Jin, Xiaoping Zhang, J Gildade Boursiquot, Steven J Burakoff

J Immunol· November 2004

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Fratricide of CD8+ cytotoxic T lymphocytes is dependent on cellular activation and perforin-mediated killing.
Michael Wei-Chih Su, Saiju Pyarajan, Jin-Hong Chang, Chao-Lan Yu, Yong-Jiu Jin, Steven J Burakoff

Eur J Immunol· September 2004

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