Publications by authors named "Steven Cardinale"

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Identification and Characterization of a Metal Binding-Independent Rift Valley Fever Virus Endonuclease Inhibitor.
Cara D Kirby, Gai Liu, Farheen Fatma, Maris R Pedlow, Narendran G-Dayanandan, Steven C Cardinale

ACS Infect Dis· September 2025

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Unsaturated fatty acid perturbation combats emerging triazole antifungal resistance in the human fungal pathogen .
Cecilia Gutierrez-Perez, Charles Puerner, Jane T Jones, Sandeep Vellanki, Elisa M Vesely, Steven Cardinale

mBio· July 2024

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Investigating N-arylpyrimidinamine (NAPA) compounds as early-stage inhibitors against human cytomegalovirus.
Andrea J Parsons, Sabrina I Ophir, Thomas J Gardner, Jailene Casado Paredes, Kathryn R Stein, Steven C Cardinale

Antiviral Res· January 2023

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Optimized Pyridazinone Nutrient Channel Inhibitors Are Potent and Specific Antimalarial Leads.
Michelle M Butler, Samanthi L Waidyarachchi, Jinfeng Shao, Son T Nguyen, Xiaoyuan Ding, Steven C Cardinale

Mol Pharmacol· September 2022

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trans-Translation inhibitors bind to a novel site on the ribosome and clear Neisseria gonorrhoeae in vivo.
Zachary D Aron, Atousa Mehrani, Eric D Hoffer, Kristie L Connolly, Pooja Srinivas, Steven C Cardinale

Nat Commun· March 2021

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Filociclovir Is an Active Antiviral Agent against Ocular Adenovirus Isolates In Vitro and in the Ad5/NZW Rabbit Ocular Model.
Eric G Romanowski, Islam T M Hussein, Steven C Cardinale, Michelle M Butler, Lucas R Morin

Pharmaceuticals (Basel)· March 2021

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Optimization of a Benzothiazole Indolene Scaffold Targeting Bacterial Cell Wall Assembly.
Jay Chauhan, Wenbo Yu, Steven Cardinale, Timothy J Opperman, Alexander D MacKerell

Drug Des Devel Ther· October 2020

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6'-Fluoro-3-deazaneplanocin: Synthesis and antiviral properties, including Ebola.
Chong Liu, Qi Chen, Steven Cardinale, Terry L Bowlin, Stewart W Schneller

Bioorg Med Chem Lett· December 2018

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Design, Synthesis, and Evaluation of Novel Prodrugs of Transition State Inhibitors of Norovirus 3CL Protease.
Anushka C Galasiti Kankanamalage, Yunjeong Kim, Athri D Rathnayake, Kevin R Alliston, Michelle M Butler, Steven C Cardinale

J Med Chem· July 2017

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Towards Development of Small Molecule Lipid II Inhibitors as Novel Antibiotics.
Jamal Chauhan, Steven Cardinale, Lei Fang, Jing Huang, Steven M Kwasny

PLoS One· June 2017

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Molecular Mechanism Underlying the Action of Influenza A Virus Fusion Inhibitor MBX2546.
Arnab Basu, Gloria Komazin-Meredith, Courtney McCarthy, Aleksandar Antanasijevic, Steven C Cardinale

ACS Infect Dis· May 2017

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TAOK3 phosphorylates the methylenecyclopropane nucleoside MBX 2168 to its monophosphate.
Gloria Komazin-Meredith, Steven C Cardinale, Katelyn Comeau, Kevin J Magalhaes, Caroll B Hartline

Antiviral Res· July 2015

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Structure-activity relationships of a novel pyranopyridine series of Gram-negative bacterial efflux pump inhibitors.
Son T Nguyen, Steven M Kwasny, Xiaoyuan Ding, Steven C Cardinale, Courtney T McCarthy

Bioorg Med Chem· May 2015

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Human cytomegalovirus UL97 kinase is involved in the mechanism of action of methylenecyclopropane analogs with 6-ether and -thioether substitutions.
Gloria Komazin-Meredith, Sunwen Chou, Mark N Prichard, Caroll B Hartline, Steven C Cardinale

Antimicrob Agents Chemother· September 2014

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Small molecule inhibitors of anthrax lethal factor toxin.
John D Williams, Atiyya R Khan, Steven C Cardinale, Michelle M Butler, Terry L Bowlin

Bioorg Med Chem· January 2014

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Human herpesvirus 6 U69 kinase phosphorylates the methylenecyclopropane nucleosides cyclopropavir, MBX 2168, and MBX 1616 to their monophosphates.
Gloria Komazin-Meredith, Steven C Cardinale, John D Williams, Norton P Peet, Mark N Prichard

Antimicrob Agents Chemother· November 2013

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Time-dependent botulinum neurotoxin serotype A metalloprotease inhibitors.
Bing Li, Steven C Cardinale, Michelle M Butler, Ramdas Pai, Jonathan E Nuss

Bioorg Med Chem· December 2011

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Identification of a small-molecule entry inhibitor for filoviruses.
Arnab Basu, Bing Li, Debra M Mills, Rekha G Panchal, Steven C Cardinale

J Virol· April 2011

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Novel Benzimidazole Inhibitors of Botulinum Neurotoxin/A Display Enzyme and Cell-Based Potency.
Steven C Cardinale, Michelle M Butler, Gordon Ruthel, Jonathan E Nuss, Laura M Wanner

Botulinum J· January 2011

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Analysis of Botulinum Neurotoxin Serotype A Metalloprotease Inhibitors: Analogs of a Chemotype for Therapeutic Development in the Context of a Three-Zone Pharmacophore.
James C Burnett, Bing Li, Ramdas Pai, Steven C Cardinale, Michelle M Butler

Open Access Bioinformatics· April 2010

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Synthesis and biological evaluation of botulinum neurotoxin a protease inhibitors.
Bing Li, Ramdas Pai, Steven C Cardinale, Michelle M Butler, Norton P Peet

J Med Chem· March 2010

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