Publications by authors named "Steven Coats"

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A B7-H4-Targeting Antibody-Drug Conjugate Shows Antitumor Activity in PARPi and Platinum-Resistant Cancers with B7-H4 Expression.
Sarah B Gitto, Margaret Whicker, Gareth Davies, Sushil Kumar, Krista Kinneer, Steven Coats

Clin Cancer Res· April 2024

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Preclinical radiolabeling, in vivo biodistribution and positron emission tomography of a novel pyrrolobenzodiazepine (PBD)-based antibody drug conjugate targeting ASCT2.
Christian Werner Wichmann, Ingrid Julienne Georgette Burvenich, Nancy Guo, Angela Rigopoulos, Alexander McDonald, Steven Coats

Nucl Med Biol· November 2023

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HIV nucleoside reverse transcriptase inhibitors.
Franck Amblard, Dharmeshkumar Patel, Eleftherios Michailidis, Steven J Coats, Mahesh Kasthuri

Eur J Med Chem· October 2022

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Diastereoselective Synthesis of 2'-Dihalopyrimidine Ribonucleoside Inhibitors of Hepatitis C Virus Replication.
Longhu Zhou, Hongwang Zhang, Chengwei Li, Coralie De Schutter, Ozkan Sari, Steven J Coats

ACS Omega· January 2022

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HER2-targeted antibody-drug conjugate induces host immunity against cancer stem cells.
Leiming Xia, Lu Wen, You Qin, Hannah E Dobson, Tao Zhang, Steven R Coats

Cell Chem Biol· May 2021

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Articulation Rate in American English in a Corpus of YouTube Videos.
Steven Coats

Lang Speech· December 2020

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Intracellular metabolism and potential cardiotoxicity of a β-D-2'--methyl-2,6-diaminopurine ribonucleoside phosphoramidate that inhibits hepatitis C virus replication.
Sijia Tao, Longhu Zhou, Hongwang Zhang, Shaoman Zhou, Sheida Amiralaei, Steven J Coats

Nucleosides Nucleotides Nucleic Acids· September 2020

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Antibody-Drug Conjugates: Future Directions in Clinical and Translational Strategies to Improve the Therapeutic Index.
Steven Coats, Marna Williams, Benjamin Kebble, Rakesh Dixit, Leo Tseng

Clin Cancer Res· September 2019

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A Biparatopic HER2-Targeting Antibody-Drug Conjugate Induces Tumor Regression in Primary Models Refractory to or Ineligible for HER2-Targeted Therapy.
John Y Li, Samuel R Perry, Vanessa Muniz-Medina, Xinzhong Wang, Leslie K Wetzel, Steven R Coats

Cancer Cell· June 2019

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Discovery of a Series of 2'-α-Fluoro,2'-β-bromo-ribonucleosides and Their Phosphoramidate Prodrugs as Potent Pan-Genotypic Inhibitors of Hepatitis C Virus.
Seema Mengshetti, Longhu Zhou, Ozkan Sari, Coralie De Schutter, Hongwang Zhang, Steven J Coats

J Med Chem· February 2019

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Synthesis and anti-HCV activity of β-d-2'-deoxy-2'-α-chloro-2'-β-fluoro and β-d-2'-deoxy-2'-α-bromo-2'-β-fluoro nucleosides and their phosphoramidate prodrugs.
Reuben Ovadia, Ahmed Khalil, Hao Li, Coralie De Schutter, Seema Mengshetti, Steven J Coats

Bioorg Med Chem· February 2019

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Synthesis and anti-HCV activity of a series of β-d-2'-deoxy-2'-dibromo nucleosides and their corresponding phosphoramidate prodrugs.
Zhe Chen, Bryan D Cox, Ethel C Garnier-Amblard, Tamara R McBrayer, Steven J Coats

Bioorg Med Chem Lett· December 2017

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Synthesis of (2S)-2-Chloro-2-fluororibolactone via Stereoselective Electrophilic Fluorination.
Coralie De Schutter, Ozkan Sari, Steven J Coats, Franck Amblard, Raymond F Schinazi

J Org Chem· December 2017

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Nucleotide Substrate Specificity of Anti-Hepatitis C Virus Nucleoside Analogs for Human Mitochondrial RNA Polymerase.
Maryam Ehteshami, Longhu Zhou, Sheida Amiralaei, Jadd R Shelton, Jong Hyun Cho, Steven J Coats

Antimicrob Agents Chemother· August 2017

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A Therapeutic Uricase with Reduced Immunogenicity Risk and Improved Development Properties.
Andrew C Nyborg, Chris Ward, Anna Zacco, Benoy Chacko, Luba Grinberg, Steven Coats

PLoS One· July 2017

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2'-Chloro,2'-fluoro Ribonucleotide Prodrugs with Potent Pan-genotypic Activity against Hepatitis C Virus Replication in Culture.
Shaoman Zhou, Sawsan Mahmoud, Peng Liu, Longhu Zhou, Maryam Ehteshami, Steven J Coats

J Med Chem· July 2017

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Synthesis and antiviral evaluation of novel heteroarylpyrimidines analogs as HBV capsid effectors.
Sebastien Boucle, Xiao Lu, Leda Bassit, Tugba Ozturk, Olivia Ollinger Russell, Steven J Coats

Bioorg Med Chem Lett· February 2017

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Synthesis and antiviral evaluation of 2',2',3',3'-tetrafluoro nucleoside analogs.
Ozkan Sari, Leda Bassit, Christina Gavegnano, Tamara R McBrayer, Louise McCormick, Steven J Coats

Tetrahedron Lett· February 2017

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Synthesis and antiviral evaluation of fluorinated acyclo-nucleosides and their phosphoramidates.
Sawsan Mahmoud, Hao Li, Tamara R McBrayer, Leda Bassit, Sherif F Hammad, Steven J Coats

Nucleosides Nucleotides Nucleic Acids· January 2017

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Biochemical Characterization of the Active Anti-Hepatitis C Virus Metabolites of 2,6-Diaminopurine Ribonucleoside Prodrug Compared to Sofosbuvir and BMS-986094.
Maryam Ehteshami, Sijia Tao, Tugba Ozturk, Longhu Zhou, Jong Hyun Cho, Steven J Coats

Antimicrob Agents Chemother· August 2016

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Development of an antibody that neutralizes soluble IgE and eliminates IgE expressing B cells.
Andrew C Nyborg, Anna Zacco, Rachel Ettinger, M Jack Borrok, Jie Zhu, Steven Coats

Cell Mol Immunol· May 2016

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A Biparatopic HER2-Targeting Antibody-Drug Conjugate Induces Tumor Regression in Primary Models Refractory to or Ineligible for HER2-Targeted Therapy.
John Y Li, Samuel R Perry, Vanessa Muniz-Medina, Xinzhong Wang, Leslie K Wetzel, Steven R Coats

Cancer Cell· January 2016

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Synthesis and Evaluation of 2,6-Modified Purine 2'-C-Methyl Ribonucleosides as Inhibitors of HCV Replication.
Longhu Zhou, Hongwang Zhang, Sijia Tao, Maryam Ehteshami, Jong Hyun Cho, Steven J Coats

ACS Med Chem Lett· January 2016

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Design, synthesis and evaluation of novel anti-HCV molecules that deliver intracellularly three highly potent NS5A inhibitors.
Sebastien Boucle, Sijia Tao, Franck Amblard, Richard A Stanton, James H Nettles, Steven J Coats

Bioorg Med Chem Lett· September 2015

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Synthesis of carbocyclic nucleoside analogs with five-membered heterocyclic nucleobases.
Jong Hyun Cho, Steven J Coats, Raymond F Schinazi

Tetrahedron Lett· June 2015

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