Publications by authors named "Steven D Buckingham"

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Automated phenotyping of mosquito larvae enables high-throughput screening for novel larvicides and offers potential for smartphone-based detection of larval insecticide resistance.
Steven D Buckingham, Frederick A Partridge, Beth C Poulton, Benjamin S Miller, Rachel A McKendry

PLoS Negl Trop Dis· June 2021

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Turning a Drug Target into a Drug Candidate: A New Paradigm for Neurological Drug Discovery?
Steven D Buckingham, Harry-Jack Mann, Olivia K Hearnden, David B Sattelle

Bioessays· September 2020

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Calcium signalling in mammalian cell lines expressing wild type and mutant human α1-Antitrypsin.
Nancy T Malintan, Steven D Buckingham, David A Lomas, David B Sattelle

Sci Rep· November 2019

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Insect toxins - selective pharmacological tools and drug/chemical leads.
Hamid S Kachel, Steven D Buckingham, David B Sattelle

Curr Opin Insect Sci· December 2018

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Improved reference genome of Aedes aegypti informs arbovirus vector control.
Benjamin J Matthews, Olga Dudchenko, Sarah B Kingan, Sergey Koren, Igor Antoshechkin, Steven D Buckingham

Nature· November 2018

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The fungal alkaloid Okaramine-B activates an L-glutamate-gated chloride channel from Ixodes scapularis, a tick vector of Lyme disease.
Shogo Furutani, Makoto Ihara, Kristin Lees, Steven D Buckingham, Frederick A Partridge

Int J Parasitol Drugs Drug Resist· August 2018

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An automated high-throughput system for phenotypic screening of chemical libraries on C. elegans and parasitic nematodes.
Frederick A Partridge, Anwen E Brown, Steven D Buckingham, Nicky J Willis, Graham M Wynne

Int J Parasitol Drugs Drug Resist· April 2018

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Modes of Action, Resistance and Toxicity of Insecticides Targeting Nicotinic Acetylcholine Receptors.
Makoto Ihara, Steven D Buckingham, Kazuhiko Matsuda, David B Sattelle

Curr Med Chem· October 2017

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Mechanisms of Action, Resistance and Toxicity of Insecticides Targeting GABA Receptors.
Steven D Buckingham, Makoto Ihara, David B Sattelle, Kazuhiko Matsuda

Curr Med Chem· October 2017

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Genomic insights into the Ixodes scapularis tick vector of Lyme disease.
Monika Gulia-Nuss, Andrew B Nuss, Jason M Meyer, Daniel E Sonenshine, R Michael Roe, Steven D Buckingham

Nat Commun· February 2016

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Actions of agonists, fipronil and ivermectin on the predominant in vivo splice and edit variant (RDLbd, I/V) of the Drosophila GABA receptor expressed in Xenopus laevis oocytes.
Kristin Lees, Maria Musgaard, Siros Suwanmanee, Steven David Buckingham, Philip Biggin

PLoS One· June 2015

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Automated, high-throughput, motility analysis in Caenorhabditis elegans and parasitic nematodes: Applications in the search for new anthelmintics.
Steven D Buckingham, Frederick A Partridge, David B Sattelle

Int J Parasitol Drugs Drug Resist· December 2014

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Glutamate-gated chloride channels of Haemonchus contortus restore drug sensitivity to ivermectin resistant Caenorhabditis elegans.
Susan K Glendinning, Steven D Buckingham, David B Sattelle, Susan Wonnacott, Adrian J Wolstenholme

PLoS One· December 2011

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A novel Caenorhabditis elegans allele, smn-1(cb131), mimicking a mild form of spinal muscular atrophy, provides a convenient drug screening platform highlighting new and pre-approved compounds.
James N Sleigh, Steven D Buckingham, Behrooz Esmaeili, Mohan Viswanathan, Edwin Cuppen

Hum Mol Genet· January 2011

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A Cys-loop mutation in the Caenorhabditis elegans nicotinic receptor subunit UNC-63 impairs but does not abolish channel function.
Andrew K Jones, Diego Rayes, Adam Al-Diwani, Thomas P R Maynard, Rachel Jones, Steven D Buckingham

J Biol Chem· January 2011

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Proteins interacting with nicotinic acetylcholine receptors: expanding functional and therapeutic horizons.
Andrew K Jones, Steven D Buckingham, David B Sattelle

Trends Pharmacol Sci· October 2010

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Alternative splicing of the Anopheles gambiae nicotinic acetylcholine receptor, Agamalphabeta9, generates both alpha and beta subunits.
Andrew K Jones, Steven D Buckingham, Laurence A Brown, David B Sattelle

Invert Neurosci· November 2009

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Allosteric modulation by benzodiazepines of GABA-gated chloride channels of an identified insect motor neurone.
Steven D Buckingham, Yoshiaki Higashino, David B Sattelle

Invert Neurosci· November 2009

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Comparative pharmacology and computational modelling yield insights into allosteric modulation of human alpha7 nicotinic acetylcholine receptors.
David B Sattelle, Steven D Buckingham, Miki Akamatsu, Kazuhiko Matsuda, Ilse S Pienaar

Biochem Pharmacol· October 2009

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Fast, automated measurement of nematode swimming (thrashing) without morphometry.
Steven D Buckingham, David B Sattelle

BMC Neurosci· July 2009

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Splice-variant- and stage-specific RNA editing of the Drosophila GABA receptor modulates agonist potency.
Andrew K Jones, Steven D Buckingham, Magdalini Papadaki, Maiko Yokota, Benedict M Sattelle

J Neurosci· April 2009

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Nicotinic acetylcholine receptor signalling: roles in Alzheimer's disease and amyloid neuroprotection.
Steven D Buckingham, Andrew K Jones, Laurence A Brown, David B Sattelle

Pharmacol Rev· March 2009

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Strategies for automated analysis of C. elegans locomotion.
Steven D Buckingham, David B Sattelle

Invert Neurosci· September 2008

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Action potential shape change in an electrically coupled network during propagation: a computer simulation.
Steven D Buckingham, Andrew N Spencer

Invert Neurosci· June 2008

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The Abeta1-42M35C mutated amyloid peptide Abeta1-42 and the 25-35 fragment fail to mimic the subtype-specificity of actions on recombinant human nicotinic acetylcholine receptors (alpha7, alpha4beta2, alpha3beta4).
Luanda J Pym, Steven D Buckingham, Victor Tsetlin, C A R Boyd, David B Sattelle

Neurosci Lett· October 2007

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