Publications by authors named "Steven Duddy"

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Development of clinically viable non-muscle myosin II small molecule inhibitors.
Laszlo Radnai, Erica J Young, Carlos Kikuti, Katalin Toth, Minghai Zhou, Steven K Duddy

Cell· August 2025

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Development of Clinically Viable Non-Muscle Myosin II Small Molecule Inhibitors with Broad Therapeutic Potential.
Laszlo Radnai, Erica J Young, Carlos Kikuti, Madalyn Hafenbreidel, Rebecca F Stremel, Steven K Duddy

bioRxiv· October 2024

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Preclinical development of an EP2 antagonist for post-seizure cognitive deficits.
Nicholas H Varvel, Radhika Amaradhi, Claudia Espinosa-Garcia, Steven Duddy, Ronald Franklin

Neuropharmacology· February 2023

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Preclinical validation of a potent γ-secretase modulator for Alzheimer's disease prevention.
Kevin D Rynearson, Moorthi Ponnusamy, Olga Prikhodko, Yuhuan Xie, Can Zhang, Steven K Duddy

J Exp Med· April 2021

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Pharmacological and Toxicological Properties of the Potent Oral -Secretase Modulator BPN-15606.
Steven L Wagner, Kevin D Rynearson, Steven K Duddy, Can Zhang, Phuong D Nguyen

J Pharmacol Exp Ther· July 2017

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Pregabalin induces hepatic hypoxia and increases endothelial cell proliferation in mice, a process inhibited by dietary vitamin E supplementation.
Kay A Criswell, Jon C Cook, Dennis Morse, Michael Lawton, Christopher Somps, Steven Duddy

Toxicol Sci· July 2012

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Hemangiosarcoma in mice administered pregabalin: analysis of genotoxicity, tumor incidence, and tumor genetics.
David Pegg, Michael Bleavins, James Herman, Zbigniew Wojcinski, Michael Graziano, Steven Duddy

Toxicol Sci· July 2012

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Key components of the mode of action for hemangiosarcoma induction in pregabalin-treated mice: evidence of increased bicarbonate, dysregulated erythropoiesis, macrophage activation, and increased angiogenic growth factors in mice but not in rats.
Kay A Criswell, Zbigniew Wojcinski, David Pegg, Mudher Albassam, Steven Duddy

Toxicol Sci· July 2012

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