Publications by authors named "Steven Isakoff"

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Current landscape of sequencing ADCs in metastatic breast cancer.
Shannon McLaughlin, Lis V Ravani, Beverly Moy, Arielle J Medford, Steven J Isakoff

Ther Adv Med Oncol· December 2025

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Leveraging real-world evidence to personalize adjuvant therapy in HR+/HER2- early breast cancer.
Yael Bar, Steven J Isakoff, Seth A Wander

JNCI Cancer Spectr· September 2025

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Selection biases in the systematic collection of breast biobank specimens.
Yael Bar, Gary X Wang, Gabrielle E Gioia, Geoffrey Fell, Shinn-Huey S Chou, Steven J Isakoff

NPJ Breast Cancer· August 2025

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TOP1 Mutations and Cross-Resistance to Antibody-Drug Conjugates in Patients with Metastatic Breast Cancer.
Rachel O Abelman, Bogang Wu, Haley Barnes, Arielle Medford, Bryanna Norden, Steven J Isakoff

Clin Cancer Res· May 2025

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Dynamic HER2-low status among patients with triple negative breast cancer (TNBC) and the impact of repeat biopsies.
Yael Bar, Geoffrey Fell, Aylin Dedeoglu, Natalie Moffett, Neelima Vidula, Steven J Isakoff

NPJ Breast Cancer· March 2025

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Adjuvant endocrine therapy with cyclin-dependent kinase 4/6 inhibitor, ribociclib, for localized hormone receptor-positive/HER2- breast cancer (LEADER).
Laura M Spring, Lauren Scarpetti, Arielle J Medford, Andrzej Niemierko, Amy Comander, Steven J Isakoff

NPJ Breast Cancer· January 2025

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A TROP2/Claudin Program Mediates Immune Exclusion to Impede Checkpoint Blockade in Breast Cancer.
Bogang Wu, Win Thant, Elena Bitman, Ting Liu, Jie Liu, Steven J Isakoff

bioRxiv· December 2024

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Adjuvant Trastuzumab Emtansine Versus Paclitaxel Plus Trastuzumab for Stage I Human Epidermal Growth Factor Receptor 2-Positive Breast Cancer: 5-Year Results and Correlative Analyses From ATEMPT.
Paolo Tarantino, Nabihah Tayob, Guillermo Villacampa, Chau Dang, Denise A Yardley, Steven J Isakoff

J Clin Oncol· November 2024

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Ipatasertib plus Paclitaxel for Patients with PIK3CA/AKT1/PTEN-Altered Locally Advanced Unresectable or Metastatic Triple-Negative Breast Cancer in the IPATunity130 Phase III Trial.
Rebecca A Dent, Sung-Bae Kim, Mafalda Oliveira, Carlos Barrios, Joyce O'Shaughnessy, Steven J Isakoff

Clin Cancer Res· October 2024

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Antibody-Drug Conjugate Sacituzumab Govitecan Enables a Sequential TOP1/PARP Inhibitor Therapy Strategy in Patients with Breast Cancer.
Aditya Bardia, Sheng Sun, Nayana Thimmiah, James T Coates, Bogang Wu, Steven J Isakoff

Clin Cancer Res· July 2024

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Searching for the "Holy Grail" of breast cancer recurrence risk: a narrative review of the hunt for a better biomarker and the promise of circulating tumor DNA (ctDNA).
Lucy Gao, Arielle Medford, Laura Spring, Yael Bar, Bonnie Hu, Steven J Isakoff

Breast Cancer Res Treat· June 2024

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Functional hemodynamic imaging markers for the prediction of pathological outcomes in breast cancer patients treated with neoadjuvant chemotherapy.
Bin Deng, Ailis Muldoon, Jayne Cormier, Nathaniel D Mercaldo, Elizabeth Niehoff, Steven J Isakoff

J Biomed Opt· June 2024

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A prospective study of HER3 expression pre and post neoadjuvant therapy of different breast cancer subtypes: implications for HER3 imaging therapy guidance.
Nicoleta Sinevici, Christine E Edmonds, Brian N Dontchos, Gary Wang, Constance D Lehman, Steven Isakoff

Breast Cancer Res· June 2024

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Genomic spectrum of actionable alterations in serial cell free DNA (cfDNA) analysis of patients with metastatic breast cancer.
Yael Bar, Jennifer C Keenan, Andrzej Niemierko, Arielle J Medford, Steven J Isakoff

NPJ Breast Cancer· April 2024

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Allosteric PI3Kα Inhibition Overcomes On-target Resistance to Orthosteric Inhibitors Mediated by Secondary PIK3CA Mutations.
Andreas Varkaris, Ferran Fece de la Cruz, Elizabeth E Martin, Bryanna L Norden, Nicholas Chevalier, Steven J Isakoff

Cancer Discov· February 2024

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First-Line Ipatasertib, Atezolizumab, and Taxane Triplet for Metastatic Triple-Negative Breast Cancer: Clinical and Biomarker Results.
Peter Schmid, Nicholas C Turner, Carlos H Barrios, Steven J Isakoff, Sung-Bae Kim

Clin Cancer Res· February 2024

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Virtual Molecular and Precision Medicine Clinic to Improve Access to Clinical Trials for Patients With Metastatic Breast Cancer: An Academic/Community Collaboration.
Laura M Spring, Lindsey Mortensen, Elizabeth Abraham, Jennifer Keenan, Arielle Medford, Steven J Isakoff

JCO Oncol Pract· January 2024

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Stressed target cancer cells drive nongenetic reprogramming of CAR T cells and solid tumor microenvironment.
Yufeng Wang, David L Drum, Ruochuan Sun, Yida Zhang, Feng Chen, Steven J Isakoff

Nat Commun· September 2023

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Feasibility of introducing a smartphone navigation application into the care of breast cancer patients (The FIONA Study).
Steven J Isakoff, Maya R Said, Agnes H Kwak, Eva Glieberman, Emily A O'Rourke

Breast Cancer Res Treat· June 2023

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Therapeutic Role of Tamoxifen for Triple-Negative Breast Cancer: Leveraging the Interaction Between ERβ and Mutant p53.
Lauren Scarpetti, Chetan C Oturkar, Dejan Juric, Maria Shellock, Giuliana Malvarosa, Steven Isakoff

Oncologist· April 2023

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Utilizing cell-free DNA to predict risk of developing brain metastases in patients with metastatic breast cancer.
Neelima Vidula, Andrzej Niemierko, Katherine Hesler, Lianne Ryan, Beverly Moy, Steven Isakoff

NPJ Breast Cancer· April 2023

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Stressed target cancer cells drive nongenetic reprogramming of CAR T cells and tumor microenvironment, overcoming multiple obstacles of CAR T therapy for solid tumors.
Yufeng Wang, David L Drum, Ruochuan Sun, Yida Zhang, Ling Yu, Steven J Isakoff

Res Sq· February 2023

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Adjuvant trastuzumab and vinorelbine for early-stage HER2+ breast cancer.
Shannon McLaughlin, Erika Nakajima, Yael Bar, Jennifer A Hutchinson, Jennifer Shin, Steven J Isakoff

Ther Adv Med Oncol· January 2023

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Treatment discontinuation, patient-reported toxicities and quality-of-life by age following trastuzumab emtansine or paclitaxel/trastuzumab (ATEMPT).
Tal Sella, Yue Zheng, Nabihah Tayob, Kathryn J Ruddy, Rachel A Freedman, Steven J Isakoff

NPJ Breast Cancer· November 2022

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Immunogenicity of SARS-CoV-2 vaccines in patients with breast cancer.
Elyssa Denault, Erika Nakajima, Vivek Naranbhai, Jennifer A Hutchinson, Lindsey Mortensen, Steven J Isakoff

Ther Adv Med Oncol· August 2022

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