Publications by authors named "Steven M Block"

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Comprehensive sequence-to-function mapping of cofactor-dependent RNA catalysis in the glmS ribozyme.
Johan O L Andreasson, Andrew Savinov, Steven M Block, William J Greenleaf

Nat Commun· April 2020

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Self-cleavage of the ribozyme core is controlled by a fragile folding element.
Andrew Savinov, Steven M Block

Proc Natl Acad Sci U S A· November 2018

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Restoring Faculty Vitality in Academic Medicine When Burnout Threatens.
Darshana T Shah, Valerie N Williams, Luanne E Thorndyke, E Eugene Marsh, Roberta E Sonnino, Steven M Block

Acad Med· July 2018

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KIF15 nanomechanics and kinesin inhibitors, with implications for cancer chemotherapeutics.
Bojan Milic, Anirban Chakraborty, Kyuho Han, Michael C Bassik, Steven M Block

Proc Natl Acad Sci U S A· May 2018

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Observing Single RNA Polymerase Molecules Down to Base-Pair Resolution.
Anirban Chakraborty, Cong A Meng, Steven M Block

Methods Mol Biol· January 2018

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Real-time observation of polymerase-promoter contact remodeling during transcription initiation.
Cong A Meng, Furqan M Fazal, Steven M Block

Nat Commun· October 2017

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Intraflagellar transport velocity is governed by the number of active KIF17 and KIF3AB motors and their motility properties under load.
Bojan Milic, Johan O L Andreasson, Daniel W Hogan, Steven M Block

Proc Natl Acad Sci U S A· August 2017

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Direct observation of processive exoribonuclease motion using optical tweezers.
Furqan M Fazal, Daniel J Koslover, Ben F Luisi, Steven M Block

Proc Natl Acad Sci U S A· December 2015

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Observation of long-range tertiary interactions during ligand binding by the TPP riboswitch aptamer.
Van K Duesterberg, Irena T Fischer-Hwang, Christian F Perez, Daniel W Hogan, Steven M Block

Elife· December 2015

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Real-time observation of the initiation of RNA polymerase II transcription.
Furqan M Fazal, Cong A Meng, Kenji Murakami, Roger D Kornberg, Steven M Block

Nature· September 2015

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RNA BIOCHEMISTRY. Factor-dependent processivity in human eIF4A DEAD-box helicase.
Cuauhtémoc García-García, Kirsten L Frieda, Kateryna Feoktistova, Christopher S Fraser, Steven M Block

Science· June 2015

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The Mechanochemical Cycle of Mammalian Kinesin-2 KIF3A/B under Load.
Johan O L Andreasson, Shankar Shastry, William O Hancock, Steven M Block

Curr Biol· May 2015

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Examining kinesin processivity within a general gating framework.
Johan O L Andreasson, Bojan Milic, Geng-Yuan Chen, Nicholas R Guydosh, William O Hancock, Steven M Block

Elife· April 2015

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Defining "faculty" in academic medicine: responding to the challenges of a changing environment.
Steven M Block, Roberta E Sonnino, Lisa Bellini

Acad Med· March 2015

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A DNA-based molecular probe for optically reporting cellular traction forces.
Brandon L Blakely, Christoph E Dumelin, Britta Trappmann, Lynn M McGregor, Colin K Choi, Steven M Block

Nat Methods· December 2014

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Single-molecule studies of riboswitch folding.
Andrew Savinov, Christian F Perez, Steven M Block

Biochim Biophys Acta· October 2014

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Kinesin processivity is gated by phosphate release.
Bojan Milic, Johan O L Andreasson, William O Hancock, Steven M Block

Proc Natl Acad Sci U S A· September 2014

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Reconstructing folding energy landscapes by single-molecule force spectroscopy.
Michael T Woodside, Steven M Block

Annu Rev Biophys· August 2014

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Transcription factors TFIIF and TFIIS promote transcript elongation by RNA polymerase II by synergistic and independent mechanisms.
Volker Schweikhard, Cong Meng, Kenji Murakami, Craig D Kaplan, Roger D Kornberg, Steven M Block

Proc Natl Acad Sci U S A· May 2014

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A pause sequence enriched at translation start sites drives transcription dynamics in vivo.
Matthew H Larson, Rachel A Mooney, Jason M Peters, Tricia Windgassen, Dhananjaya Nayak, Steven M Block

Science· May 2014

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Single-molecule studies of RNAPII elongation.
Jing Zhou, Volker Schweikhard, Steven M Block

Biochim Biophys Acta· January 2013

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Efficient reconstitution of transcription elongation complexes for single-molecule studies of eukaryotic RNA polymerase II.
Murali Palangat, Matthew H Larson, Xiaopeng Hu, Averell Gnatt, Steven M Block

Transcription· November 2012

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Binding and translocation of termination factor rho studied at the single-molecule level.
Daniel J Koslover, Furqan M Fazal, Rachel A Mooney, Robert Landick, Steven M Block

J Mol Biol· November 2012

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Direct observation of cotranscriptional folding in an adenine riboswitch.
Kirsten L Frieda, Steven M Block

Science· October 2012

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Trigger loop dynamics mediate the balance between the transcriptional fidelity and speed of RNA polymerase II.
Matthew H Larson, Jing Zhou, Craig D Kaplan, Murali Palangat, Roger D Kornberg, Steven M Block

Proc Natl Acad Sci U S A· April 2012

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