Publications by authors named "Steven M Rowe"

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A ferret model demonstrates sustained fibrosis, restrictive physiology, and airway proximalization.
Jacelyn E Peabody Lever, Qian Li, Nikoleta Pavelkova, Shah S Hussain, Sayan Bakshi, Steven M Rowe

NPJ Regen Med· November 2025

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ACE-2 blockade and TMPRSS2 inhibition mitigate SARS-CoV-2 severity following cigarette smoke exposure in airway epithelial cells .
Shah S Hussain, Emily Falk Libby, Jacelyn E Peabody Lever, Jennifer L Tipper, Scott E Phillips, Steven M Rowe

Mol Ther Nucleic Acids· September 2025

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Identity, functional consequences, and context effects of amino acids inserted during suppression of CFTR nonsense mutations.
Kari Thrasher, Jianguo Chen, Lianwu Fu, Dominique Benson, Jenna Ekstrom, Steven M Rowe

J Cyst Fibros· September 2025

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is influenced by mucus accumulation, airway inflammation and cystic fibrosis transmembrane conductance regulator function.
T Spencer Poore, Anh Nguyen, Levi Schaefers, Anna Solomonik, Ashleigh Rieglers, Steven M Rowe

ERJ Open Res· September 2025

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Glycemia and Insulin Secretion in Cystic Fibrosis 2 Years After Elexacaftor/Tezacaftor/Ivacaftor: PROMISE-ENDO.
Christine L Chan, Meghan Shirley Bezerra, Darko Stefanovski, Robert J Gallop, Rachel Walega, Steven M Rowe

J Clin Endocrinol Metab· August 2025

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Fecal microbiota changes in people with cystic fibrosis after 6 months of elexacaftor/tezacaftor/ivacaftor: Findings from the promise study.
Jennifer T Duong, Hillary S Hayden, Adrian J Verster, Christopher E Pope, Carson Miller, Steven M Rowe

J Cyst Fibros· July 2025

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Hyaluronan Ameliorates Viral Pneumonia in Mice and Humans by Inhibiting E2F1 Transcription Factor.
Vandy P Stober, Carol S Trempus, Flavia Galdi, Negin P Martin, Wesley Gladwell, Steven M Rowe

Am J Respir Cell Mol Biol· July 2025

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Lumacaftor inhibits channel activity of rescued F508del cystic fibrosis transmembrane conductance regulator.
Adam D Ambrosetti, Zachary J Hagedorn, Taylor R Bono, Hui Wen, Rodney Nguyen, Steven M Rowe

Am J Physiol Lung Cell Mol Physiol· June 2025

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Ivacaftor for Chronic Obstructive Pulmonary Disease: Results from a Phase 2, Randomized Controlled Trial.
Kadambari Vijaykumar, George M Solomon, Jennifer Guimbellot, Edward P Acosta, Pradeep G Bhambhavni, Steven M Rowe

Am J Respir Crit Care Med· May 2025

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AirSeg: Learnable Interconnected Attention Framework for Robust Airway Segmentation.
Chetana Krishnan, Shah Hussain, Denise Stanford, Venkata Sthanam, Sandeep Bodduluri, Steven M Rowe

J Imaging Inform Med· May 2025

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Toward in vivo bronchoscopic functional CFTR assessment using a short circuit current measurement probe.
David O Otuya, Zhongyu Liu, Reny Joseph, Mohammed A Hanafy, Kadambari Vijaykumar, Steven M Rowe

Am J Physiol Lung Cell Mol Physiol· February 2025

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Elexacaftor/Tezacaftor/Ivacaftor Markedly Reduces in Cystic Fibrosis.
Sarah J Morgan, David P Nichols, Windy Ni, Gina Hong, Stephen J Salipante, Steven M Rowe

Am J Respir Crit Care Med· November 2024

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Metachrony drives effective mucociliary transport via a calcium-dependent mechanism.
Jacelyn E Peabody Lever, K Brett Turner, Courtney M Fernandez, Hui Min Leung, Shah Saddad Hussain, Steven M Rowe

Am J Physiol Lung Cell Mol Physiol· September 2024

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Association between biomarkers of tobacco smoke exposure and clinical efficacy of ivacaftor in the G551D observational trial (GOAL).
Elizabeth Baker, William T Harris, Jennifer S Guimbellot, Kyle Bliton, Steven M Rowe

J Cyst Fibros· September 2024

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Elexacaftor/tezacaftor/ivacaftor's effects on cystic fibrosis infections are maintained, but not increased, after 3.5 years of treatment.
Sarah J Morgan, Ellis Coulter, Hannah L Betts, George M Solomon, John P Clancy, Steven M Rowe

J Clin Invest· September 2024

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Comparison of a novel potentiator of CFTR channel activity to ivacaftor in ameliorating mucostasis caused by cigarette smoke in primary human bronchial airway epithelial cells.
Adrian Constantin Tanjala, Jia Xin Jiang, Paul D W Eckford, Mohabir Ramjeesingh, Canhui Li, Steven M Rowe

Respir Res· July 2024

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Reduced sialylation of airway mucin impairs mucus transport by altering the biophysical properties of mucin.
Elex S Harris, Hannah J McIntire, Marina Mazur, Hinnerk Schulz-Hildebrandt, Hui Min Leung, Steven M Rowe

Sci Rep· July 2024

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Pulmonary Fibrosis Ferret Model Demonstrates Sustained Fibrosis, Restrictive Physiology, and Aberrant Repair.
Jacelyn E Peabody Lever, Qian Li, Nikoleta Pavelkova, Shah S Hussain, Sayan Bakshi, Steven M Rowe

bioRxiv· June 2024

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Loss of cell junctional components and matrix alterations drive cell desquamation and fibrotic changes in Idiopathic Pulmonary Fibrosis.
Rachana R Chandran, Preethi Vijayaraj, Rolando Garcia-Milian, Jade King, Kristen Castillo, Steven M Rowe

bioRxiv· June 2024

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ACE-2 Blockade & TMPRSS2 Inhibition Mitigate SARS-CoV-2 Severity Following Cigarette Smoke Exposure in Airway Epithelial Cells In Vitro.
Shah S Hussain, Emily Falk Libby, Jacelyn E Peabody Lever, Jennifer L Tipper, Scott E Phillips, Steven M Rowe

bioRxiv· June 2024

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The effect of discontinuing hypertonic saline or dornase alfa on mucociliary clearance in elexacaftor/tezacaftor/ivacaftor treated people with cystic fibrosis: The SIMPLIFY-MCC Study.
Scott H Donaldson, Timothy E Corcoran, Joseph M Pilewski, Beth L Laube, Peter Mogayzel, Steven M Rowe

J Cyst Fibros· May 2024

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Alterations in the fecal microbiota in patients with advanced cystic fibrosis liver disease after 6 months of elexacaftor/tezacaftor/ivacaftor.
Jennifer T Duong, Christopher E Pope, Hillary S Hayden, Carson Miller, Stephen J Salipante, Steven M Rowe

J Cyst Fibros· May 2024

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Reduced Sialylation of Airway Mucin Impairs Mucus Transport by Altering the Biophysical Properties of Mucin.
Elex S Harris, Hannah J McIntire, Marina Mazur, Hinnerk Schulz-Hildebrandt, Hui Min Leung, Steven M Rowe

Res Sq· May 2024

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Longitudinal improvements in clinical and functional outcomes following initiation of elexacaftor/tezacaftor/ivacaftor in patients with cystic fibrosis.
Kadambari Vijaykumar, Hui Min Leung, Amilcar Barrios, Justin Wade, Heather Y Hathorne, Steven M Rowe

Heliyon· April 2024

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Comparison of a novel potentiator of CFTR channel activity to ivacaftor in ameliorating mucostasis caused by cigarette smoke in primary human bronchial airway epithelial cells.
Adrian Constantin Tanjala, Jia Xin Jiang, Paul D W Eckford, Mohabir Ramjeesingh, Canhui Li, Steven M Rowe

bioRxiv· March 2024

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