Publications by authors named "Steven Wagner"

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Multi-omic analysis of meningeal cerebral amyloid angiopathy reveals enrichment of unsubstituted glucosamine and extracellular proteins.
Joshua E Mayfield, Alexander J Rajic, Patricia Aguilar-Calvo, Katrin Soldau, Samantha Flores, Steven L Wagner

J Neuropathol Exp Neurol· May 2025

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Integrative multiomics reveals common endotypes across PSEN1, PSEN2, and APP mutations in familial Alzheimer's disease.
Phoebe Valdes, Andrew B Caldwell, Qing Liu, Michael Q Fitzgerald, Srinivasan Ramachandran, Steven L Wagner

Alzheimers Res Ther· January 2025

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PS1/gamma-secretase acts as rogue chaperone of glutamate transporter EAAT2/GLT-1 in Alzheimer's disease.
Florian Perrin, Lauren C Anderson, Shane P C Mitchell, Priyanka Sinha, Yuliia Turchyna, Steven L Wagner

Acta Neuropathol Commun· October 2024

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PS1/gamma-secretase acts as rogue chaperone of glutamate transporter EAAT2/GLT-1 in Alzheimer's disease.
Florian Perrin, Lauren C Anderson, Shane P C Mitchell, Priyanka Sinha, Yuliia Turchyna, Steven L Wagner

Res Sq· November 2023

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Endotype reversal as a novel strategy for screening drugs targeting familial Alzheimer's disease.
Andrew B Caldwell, Qing Liu, Can Zhang, Gary P Schroth, Douglas R Galasko, Steven L Wagner

Alzheimers Dement· November 2022

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Transcriptomic profiling of sporadic Alzheimer's disease patients.
Andrew B Caldwell, Balaji G Anantharaman, Srinivasan Ramachandran, Phuong Nguyen, Qing Liu, Steven L Wagner

Mol Brain· October 2022

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The GSM BPN-15606 as a Potential Candidate for Preventative Therapy in Alzheimer's Disease.
Olga Prikhodko, Kevin D Rynearson, Travis Sekhon, Mike M Mante, Phuong D Nguyen, Steven L Wagner

J Alzheimers Dis· May 2021

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Preclinical validation of a potent γ-secretase modulator for Alzheimer's disease prevention.
Kevin D Rynearson, Moorthi Ponnusamy, Olga Prikhodko, Yuhuan Xie, Can Zhang, Steven L Wagner

J Exp Med· April 2021

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Molecular imaging of Alzheimer's disease-related gamma-secretase in mice and nonhuman primates.
Yulong Xu, Changning Wang, Hsiao-Ying Wey, Yingxia Liang, Zude Chen, Steven L Wagner

J Exp Med· December 2020

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Design and synthesis of novel methoxypyridine-derived gamma-secretase modulators.
Kevin D Rynearson, Ronald N Buckle, R Jason Herr, Nicholas J Mayhew, Xinchao Chen, Steven L Wagner

Bioorg Med Chem· November 2020

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Dedifferentiation and neuronal repression define familial Alzheimer's disease.
Andrew B Caldwell, Qing Liu, Gary P Schroth, Douglas R Galasko, Shauna H Yuan, Steven L Wagner

Sci Adv· November 2020

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Optically accessible generic exhaust gas test bench for the investigation of fundamental SCR-relevant processes.
Anna Schmidt, Sani van der Kley, Steven Wagner

Appl Opt· August 2020

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γ-Secretase Partitioning into Lipid Bilayers Remodels Membrane Microdomains after Direct Insertion.
Marilia Barros, William J Houlihan, Chelsea J Paresi, Matthew Brendel, Kevin D Rynearson, Steven L Wagner

Langmuir· June 2020

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Amyloid-β42/40 ratio drives tau pathology in 3D human neural cell culture models of Alzheimer's disease.
Sang Su Kwak, Kevin J Washicosky, Emma Brand, Djuna von Maydell, Jenna Aronson, Steven L Wagner

Nat Commun· March 2020

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Efficient Bayesian inference of absorbance spectra from transmitted intensity spectra.
Johannes Emmert, Samuel J Grauer, Steven Wagner, Kyle J Daun

Opt Express· September 2019

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Malignant phyllodes tumor in Lynch syndrome: a case report.
Shayma Kazmi, Steven Wagner, Rebecca Heintzelman, Melanie Corbman

J Med Case Rep· July 2019

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Utilization of a Radiation Safety Time-Out Reduces Radiation Exposure During Electrophysiology Procedures.
Anthony Aizer, Jessica K Qiu, Austin V Cheng, Patrick B Wu, Douglas S Holmes, Steven R Wagner

JACC Clin Electrophysiol· May 2019

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APP-Mediated Signaling Prevents Memory Decline in Alzheimer's Disease Mouse Model.
Carole Deyts, Mary Clutter, Nicholas Pierce, Paramita Chakrabarty, Thomas B Ladd, Steven L Wagner

Cell Rep· April 2019

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Comparison of two measurement strategies to obtain the residence time distribution in combustion chambers using tunable diode laser absorption spectroscopy.
Sebastian Bürkle, Lukas G Becker, Maria A Agizza, Andreas Dreizler, Steven Wagner

Appl Opt· April 2019

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Cholesterol Metabolism Is a Druggable Axis that Independently Regulates Tau and Amyloid-β in iPSC-Derived Alzheimer's Disease Neurons.
Rik van der Kant, Vanessa F Langness, Cheryl M Herrera, Daniel A Williams, Lauren K Fong, Steven L Wagner

Cell Stem Cell· March 2019

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Reduction of the expression of the late-onset Alzheimer's disease (AD) risk-factor does not affect amyloid pathology in an AD mouse model.
Robert J Andrew, Pierre De Rossi, Phuong Nguyen, Haley R Kowalski, Aleksandra J Recupero, Steven L Wagner

J Biol Chem· March 2019

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PolySpec: polynomial spectrum models for fast and light-weight spectroscopic evaluation.
Johannes Emmert, Niels Göran Blume, Andreas Dreizler, Steven Wagner

Appl Opt· December 2018

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Data analysis and uncertainty estimation in supercontinuum laser absorption spectroscopy.
Johannes Emmert, Niels Göran Blume, Andreas Dreizler, Steven Wagner

Sci Rep· July 2018

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Lack of BACE1 S-palmitoylation reduces amyloid burden and mitigates memory deficits in transgenic mouse models of Alzheimer's disease.
Robert J Andrew, Celia G Fernandez, Molly Stanley, Hong Jiang, Phuong Nguyen, Steven L Wagner

Proc Natl Acad Sci U S A· November 2017

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Soluble Gamma-secretase Modulators Attenuate Alzheimer's β-amyloid Pathology and Induce Conformational Changes in Presenilin 1.
Frank Raven, Joseph F Ward, Katarzyna M Zoltowska, Yu Wan, Enjana Bylykbashi, Steven L Wagner

EBioMedicine· October 2017

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