Publications by authors named "Streamson Chua"

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Liver-innervating vagal sensory neurons are indispensable for the development of hepatic steatosis and anxiety-like behavior in diet-induced obese mice.
Jiyeon Hwang, Sangbhin Lee, Junichi Okada, Li Liu, Jeffrey E Pessin, Streamson C Chua

Nat Commun· January 2025

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Liver-innervating vagal sensory neurons are indispensable for the development of hepatic steatosis and anxiety-like behavior in diet-induced obese mice.
Jiyeon Hwang, Sangbhin Lee, Junichi Okada, Li Liu, Jeffrey E Pessin, Streamson C Chua

bioRxiv· December 2024

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The gut signals to AGRP-expressing cells of the pituitary to control glucose homeostasis.
Shun-Mei Liu, Bruno Ifebi, Fred Johnson, Alison Xu, Jacquelin Ho, Streamson Chua

J Clin Invest· April 2023

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Cyclin-dependent kinase 4/6 inhibitors require an arcuate-to-paraventricular hypothalamus melanocortin circuit to treat diet-induced obesity.
Niloy Jafar Iqbal, Gary J Schwartz, Hongling Zhao, Liang Zhu, Streamson Chua

Am J Physiol Endocrinol Metab· March 2021

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Conversion of the death inhibitor ARC to a killer activates pancreatic β cell death in diabetes.
Wendy M McKimpson, Yun Chen, James A Irving, Min Zheng, Jeremy Weinberger, Streamson C Chua

Dev Cell· March 2021

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Optogenetic stimulation of the liver-projecting melanocortinergic pathway promotes hepatic glucose production.
Eunjin Kwon, Hye-Young Joung, Shun-Mei Liu, Streamson C Chua, Gary J Schwartz

Nat Commun· December 2020

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Leptin-mediated differential regulation of microsomal triglyceride transfer protein in the intestine and liver affects plasma lipids.
Jahangir Iqbal, Eduardo Mascareno, Streamson Chua, M Mahmood Hussain

J Biol Chem· March 2020

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Neuronal Cell Cycle Events Link Caloric Intake to Obesity.
Niloy Iqbal, LIang Zhu, Streamson C Chua

Trends Endocrinol Metab· January 2020

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Cutting Edge: Elevated Leptin during Diet-Induced Obesity Reduces the Efficacy of Tumor Immunotherapy.
Katherine A Murphy, Britnie R James, Frances V Sjaastad, Tamara A Kucaba, Hyunjoon Kim, Streamson C Chua

J Immunol· October 2018

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Cyclin-dependent kinase 4 is a preclinical target for diet-induced obesity.
Niloy Jafar Iqbal, Zhonglei Lu, Shun Mei Liu, Gary J Schwartz, Streamson Chua

JCI Insight· September 2018

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Activation of temperature-sensitive TRPV1-like receptors in ARC POMC neurons reduces food intake.
Jae Hoon Jeong, Dong Kun Lee, Shun-Mei Liu, Streamson C Chua, Gary J Schwartz

PLoS Biol· April 2018

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A gut-brain axis regulating glucose metabolism mediated by bile acids and competitive fibroblast growth factor actions at the hypothalamus.
Shunmei Liu, Genevieve Marcelin, Clemence Blouet, Jae Hoon Jeong, Young-Hwan Jo, Streamson Chua

Mol Metab· February 2018

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Leptin Function and Regulation.
Yiying Zhang, Streamson Chua

Compr Physiol· December 2017

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Single-Cell Gene Expression Analysis of Cholinergic Neurons in the Arcuate Nucleus of the Hypothalamus.
Jae Hoon Jeong, Young Jae Woo, Streamson Chua, Young-Hwan Jo

PLoS One· August 2017

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ARC is essential for maintaining pancreatic islet structure and β-cell viability during type 2 diabetes.
Wendy M McKimpson, Min Zheng, Streamson C Chua, Jeffrey E Pessin, Richard N Kitsis

Sci Rep· August 2017

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mTORC1 in AGRP neurons integrates exteroceptive and interoceptive food-related cues in the modulation of adaptive energy expenditure in mice.
Luke K Burke, Tamana Darwish, Althea R Cavanaugh, Sam Virtue, Emma Roth, Streamson Chua

Elife· May 2017

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FGF 19 and Bile Acids Increase Following Roux-en-Y Gastric Bypass but Not After Medical Management in Patients with Type 2 Diabetes.
Saachi Sachdev, Qi Wang, Charles Billington, John Connett, Leaque Ahmed, Streamson Chua

Obes Surg· May 2016

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Leptin potentiates astrogenesis in the developing hypothalamus.
Daniele M Rottkamp, Ivan A Rudenko, Matthew T Maier, Sahar Roshanbin, Ernie Yulyaningsih, Streamson Chua

Mol Metab· November 2015

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Cholinergic neurons in the dorsomedial hypothalamus regulate mouse brown adipose tissue metabolism.
Jae Hoon Jeong, Dong Kun Lee, Clemence Blouet, Henry H Ruiz, Christoph Buettner, Streamson Chua

Mol Metab· June 2015

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Loss of the RNA polymerase III repressor MAF1 confers obesity resistance.
Nicolas Bonhoure, Ashlee Byrnes, Robyn D Moir, Wassim Hodroj, Frédéric Preitner, Streamson C Chua

Genes Dev· May 2015

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Interplay between glucose and leptin signalling determines the strength of GABAergic synapses at POMC neurons.
Dong Kun Lee, Jae Hoon Jeong, Sung-Kun Chun, Streamson Chua, Young-Hwan Jo

Nat Commun· March 2015

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The antidepressant trans-2-phenylcyclopropylamine protects mice from high-fat-diet-induced obesity.
Adi Shemesh, Arian Abdulla, Fajun Yang, Streamson C Chua, Jeffrey E Pessin

PLoS One· January 2015

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Role of melanocortin signaling in neuroendocrine and metabolic actions of leptin in male rats with uncontrolled diabetes.
Thomas H Meek, Miles E Matsen, Vincent Damian, Alex Cubelo, Streamson C Chua

Endocrinology· November 2014

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Intestinal deletion of leptin signaling alters activity of nutrient transporters and delayed the onset of obesity in mice.
Annabelle Tavernier, Jean-Baptiste Cavin, Maude Le Gall, Robert Ducroc, Raphaël G P Denis, Streamson Chua

FASEB J· September 2014

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Central action of FGF19 reduces hypothalamic AGRP/NPY neuron activity and improves glucose metabolism.
Geneviève Marcelin, Young-Hwan Jo, Xiaosong Li, Gary J Schwartz, Ying Zhang, Streamson Chua

Mol Metab· February 2014

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