Publications by authors named "Struan F A Grant"

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3D chromatin-based variant-to-gene maps across 57 human cell types reveal the cellular and genetic architecture of autoimmune disease susceptibility.
Khanh B Trang, Prabhat Sharma, Laura Cook, Zachary Mount, Rajan M Thomas, Struan F A Grant

Genome Biol· December 2025

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Integrated genomic analysis and CRISPRi implicates in Alzheimer's disease risk.
Yuk Yee Leung, Pavel P Kuksa, Luke Carter, Jeffrey Cifello, Emily Greenfest-Allen, Struan F A Grant

NPJ Dement· December 2025

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Race-neutral Pediatric Reference Ranges for Bone Mineral Density Predict Prospective Fractures in Childhood.
Babette S Zemel, Karen K Winer, Andrea Kelly, David S Freedman, Jonathan A Mitchell, Struan F A Grant

J Clin Endocrinol Metab· October 2025

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GWAS-informed data integration and non-coding CRISPRi screen illuminate genetic etiology of bone mineral density.
Mitchell Conery, James A Pippin, Yadav Wagley, Khanh Trang, Matthew C Pahl, Struan F A Grant

Genome Biol· October 2025

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Large-scale multiomic analysis identifies non-coding somatic driver mutations and nominates as a driver gene for pancreatic ductal adenocarcinoma.
Jun Zhong, Aidan O'Brien, Minal B Patel, Daina Eiser, Michael Mobaraki, Struan F A Grant

Gut· October 2025

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The gSOS Polygenic Score is Associated with Bone Density and Fracture Risk in Childhood.
Jonathan A Mitchell, Jonathan Bradfield, Shana E McCormack, Alessandra Chesi, Heidi J Kalkwarf, Struan F A Grant

J Bone Miner Res· October 2025

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Protocol for discovering genetic variants associated with ATAC-seq footprint-inferred transcription factor binding.
Max F Dudek, Brandon M Wenz, Benjamin F Voight, Laura Almasy, Struan F A Grant

STAR Protoc· October 2025

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Insomnia's Psychiatric Health Connection Through Shared Cellular Programs.
Amber J Zimmerman, Struan F A Grant, Philip Gehrman

Sleep· October 2025

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Polygenic prediction of body mass index and obesity through the life course and across ancestries.
Roelof A J Smit, Kaitlin H Wade, Qin Hui, Joshua D Arias, Xianyong Yin, Struan F A Grant

Nat Med· September 2025

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Accelerating Medicines Partnership in Type 2 Diabetes and Common Metabolic Diseases: Collaborating to Maximize the Value of Genetic and Genomic Data.
Maria C Costanzo, Beena Akolkar, Melina Claussnitzer, Jose C Florez, Anna L Gloyn, Struan F A Grant

Diabetes· July 2025

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Prevalence and predictors of low bone mineral density in pediatric inflammatory bowel disease.
Sharmistha Rudra, Kanak Kennedy, Sarah Neukrug, Jing Huang, Diana L Cousminer, Struan F A Grant

J Pediatr Gastroenterol Nutr· July 2025

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Mapping chromatin interactions at melanoma susceptibility loci uncovers distant cis-regulatory gene targets.
Rohit Thakur, Mai Xu, Hayley Sowards, Joshuah Yon, Lea Jessop, Struan F A Grant

Am J Hum Genet· July 2025

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Characterization of non-coding variants associated with transcription-factor binding through ATAC-seq-defined footprint QTLs in liver.
Max F Dudek, Brandon M Wenz, Christopher D Brown, Benjamin F Voight, Laura Almasy, Struan F A Grant

Am J Hum Genet· June 2025

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Parental autoimmunity genetics and offspring type 1 diabetes risk.
Anthony M Gacita, Struan F A Grant

Cell Genom· June 2025

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Integrated genomic analysis and CRISPRi implicates in Alzheimer's disease risk.
Yuk Yee Leung, Pavel P Kuksa, Luke Carter, Jeffrey Cifello, Emily Greenfest-Allen, Struan F A Grant

medRxiv· June 2025

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Multimodal analysis of hematopoiesis reveals blood cell-specific genetic impacts on complex disease traits.
Rong Qiu, Khanh B Trang, Carson Shalaby, James A Pippin, James Garifallou, Struan F A Grant

bioRxiv· May 2025

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Trans-ancestry genome-wide association study of childhood body mass index identifies novel loci and age-specific effects.
Carolina G Downie, Poojan Shrestha, Samson Okello, Mohammad Yaser, Harold H Lee, Struan F A Grant

HGG Adv· April 2025

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The gSOS Polygenic Score is Associated with Bone Density and Fracture Risk in Childhood.
Jonathan A Mitchell, Jonathan Bradfield, Shana E McCormack, Alessandra Chesi, Heidi J Kalkwarf, Struan F A Grant

medRxiv· April 2025

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Trans-ancestry genome-wide association meta-analysis of gallstone disease.
Junghyun Lim, Marijana Vujkovic, Michael G Levin, Kim Lorenz, Benjamin F Voight, Struan F A Grant

medRxiv· March 2025

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3D genomic features across >50 diverse cell types reveal insights into the genomic architecture of childhood obesity.
Khanh B Trang, Matthew C Pahl, James A Pippin, Chun Su, Sheridan H Littleton, Struan F A Grant

Elife· January 2025

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A framework for conducting GWAS using repeated measures data with an application to childhood BMI.
Kimberley Burrows, Anni Heiskala, Jonathan P Bradfield, Zhanna Balkhiyarova, Lijiao Ning, Struan F A Grant

Nat Commun· November 2024

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Mapping chromatin interactions at melanoma susceptibility loci and cell-type specific dataset integration uncovers distant gene targets of -regulation.
Rohit Thakur, Mai Xu, Hayley Sowards, Joshuah Yon, Lea Jessop, Struan F A Grant

medRxiv· November 2024

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Translation of genome-wide association study: from genomic signals to biological insights.
Winter S Bruner, Struan F A Grant

Front Genet· October 2024

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Cross-species evidence for a developmental origin of adult hypersomnia with loss of synaptic adhesion molecules .
Kyla Mace, Amber Zimmerman, Alessandra Chesi, Fusun Doldur-Balli, Hayle Kim, Struan F A Grant

bioRxiv· September 2024

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Characterization of non-coding variants associated with transcription factor binding through ATAC-seq-defined footprint QTLs in liver.
Max F Dudek, Brandon M Wenz, Christopher D Brown, Benjamin F Voight, Laura Almasy, Struan F A Grant

bioRxiv· September 2024

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