Publications by authors named "Stuart Caldwell"

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Simultaneous and sensitive quantification of protein and low molecular weight persulfides, polysulfides and HS in biological samples.
Jan Lj Miljkovic, Nils Burger, Chak Shun Yu, Alexander H Harkiss, Stefan Warrington, Stuart T Caldwell

Nat Commun· December 2025

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Sub-organellar mitochondrial hydrogen peroxide observed using a SNAP tag targeted coumarin-based fluorescent reporter.
Ross Eaglesfield, Erika Fernandez-Vizarra, Erik Lacko, Stuart T Caldwell, Nikki L Sloan

Redox Biol· March 2025

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Incorporating a Polyethyleneglycol Linker to Enhance the Hydrophilicity of Mitochondria-Targeted Triphenylphosphonium Constructs.
Shinpei Uno, Alexander H Harkiss, Roy Chowdhury, Stuart T Caldwell, Tracy A Prime

Chembiochem· June 2023

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Rapid and selective generation of HS within mitochondria protects against cardiac ischemia-reperfusion injury.
Jan Lj Miljkovic, Nils Burger, Justyna M Gawel, John F Mulvey, Abigail A I Norman, Stuart T Caldwell

Redox Biol· September 2022

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Ester Prodrugs of Malonate with Enhanced Intracellular Delivery Protect Against Cardiac Ischemia-Reperfusion Injury In Vivo.
Hiran A Prag, Laura Pala, Duvaraka Kula-Alwar, John F Mulvey, Du Luping, Stuart T Caldwell

Cardiovasc Drugs Ther· February 2022

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Nrf2 is activated by disruption of mitochondrial thiol homeostasis but not by enhanced mitochondrial superoxide production.
Filip Cvetko, Stuart T Caldwell, Maureen Higgins, Takafumi Suzuki, Masayuki Yamamoto

J Biol Chem· August 2021

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Photoactivated release of membrane impermeant sulfonates inside cells.
Stuart T Caldwell, Sean N O'Byrne, Calum Wilson, Filip Cvetko, Michael P Murphy

Chem Commun (Camb)· April 2021

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Targeting Methylglyoxal in Diabetic Kidney Disease Using the Mitochondria-Targeted Compound MitoGamide.
Sih Min Tan, Runa S J Lindblom, Mark Ziemann, Adrienne Laskowski, Cesare Granata, Stuart T Caldwell

Nutrients· April 2021

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Tetra-arylborate lipophilic anions as targeting groups.
Kishore K Gaddale Devanna, Justyna M Gawel, Tracy A Prime, Filip Cvetko, Cristiane Benincá, Stuart T Caldwell

Chem Commun (Camb)· March 2021

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Confirmation of the Cardioprotective Effect of MitoGamide in the Diabetic Heart.
Min Park, Takanori Nishimura, Carlos D Baeza-Garza, Stuart T Caldwell, Pamela Boon Li Pun

Cardiovasc Drugs Ther· December 2020

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Selective Delivery of Dicarboxylates to Mitochondria by Conjugation to a Lipophilic Cation via a Cleavable Linker.
Hiran A Prag, Duvaraka Kula-Alwar, Laura Pala, Stuart T Caldwell, Timothy E Beach

Mol Pharm· September 2020

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Enhancing the Mitochondrial Uptake of Phosphonium Cations by Carboxylic Acid Incorporation.
Laura Pala, Hans M Senn, Stuart T Caldwell, Tracy A Prime, Stefan Warrington

Front Chem· September 2020

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Correction to: The Mitochondria-Targeted Methylglyoxal Sequestering Compound, MitoGamide, Is Cardioprotective in the Diabetic Heart.
Mitchel Tate, Gavin C Higgins, Miles J De Blasio, Runa Lindblom, Darnel Prakoso, Stuart T Caldwell

Cardiovasc Drugs Ther· April 2020

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A sensitive mass spectrometric assay for mitochondrial CoQ pool redox state in vivo.
Nils Burger, Angela Logan, Tracy A Prime, Amin Mottahedin, Stuart T Caldwell

Free Radic Biol Med· February 2020

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The Mitochondria-Targeted Methylglyoxal Sequestering Compound, MitoGamide, Is Cardioprotective in the Diabetic Heart.
Mitchel Tate, Gavin C Higgins, Miles J De Blasio, Runa Lindblom, Darnel Prakoso, Stuart T Caldwell

Cardiovasc Drugs Ther· December 2019

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Succinate accumulation drives ischaemia-reperfusion injury during organ transplantation.
Jack L Martin, Ana S H Costa, Anja V Gruszczyk, Timothy E Beach, Fay M Allen, Stuart T Caldwell

Nat Metab· September 2019

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Selective mitochondrial superoxide generation in vivo is cardioprotective through hormesis.
Salvatore Antonucci, John F Mulvey, Nils Burger, Moises Di Sante, Andrew R Hall, Stuart T Caldwell

Free Radic Biol Med· April 2019

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Selective Disruption of Mitochondrial Thiol Redox State in Cells and In Vivo.
Lee M Booty, Justyna M Gawel, Filip Cvetko, Stuart T Caldwell, Andrew R Hall

Cell Chem Biol· March 2019

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Mitochondrial oxidative stress causes insulin resistance without disrupting oxidative phosphorylation.
Daniel J Fazakerley, Annabel Y Minard, James R Krycer, Kristen C Thomas, Jacqueline Stöckli, Stuart T Caldwell

J Biol Chem· May 2018

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Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1.
Evanna L Mills, Dylan G Ryan, Hiran A Prag, Dina Dikovskaya, Deepthi Menon, Stuart T Caldwell

Nature· April 2018

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Unusual presentation of long-lost inferior vena cava filter.
Nicola Davis, Andrew D MacCormick, Stuart Caldwell

ANZ J Surg· March 2018

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Methionine sulfoxide reductase B3 requires resolving cysteine residues for full activity and can act as a stereospecific methionine oxidase.
Zhenbo Cao, Lorna Mitchell, Oliver Hsia, Miriam Scarpa, Stuart T Caldwell

Biochem J· February 2018

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MitoNeoD: A Mitochondria-Targeted Superoxide Probe.
Maria M Shchepinova, Andrew G Cairns, Tracy A Prime, Angela Logan, Andrew M James, Stuart T Caldwell

Cell Chem Biol· October 2017

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Synthesis of an azido-tagged low affinity ratiometric calcium sensor.
Stuart T Caldwell, Andrew G Cairns, Marnie Olson, Susan Chalmers, Mairi Sandison

Tetrahedron· December 2015

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Protein-mediated dethreading of a biotin-functionalised pseudorotaxane.
Stuart T Caldwell, Catherine Maclean, Mathis Riehle, Alan Cooper, Margaret Nutley

Org Biomol Chem· January 2014

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