Publications by authors named "Lorna Mitchell"

Claim this Profile
B
Biochemical and structural basis for the pharmacological inhibition of nuclear hormone receptor PPARγ by inverse agonists.
Sean Irwin, Craig Karr, Craig Furman, Jennifer Tsai, Patricia Gee, Lorna Mitchell

J Biol Chem· November 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
Anti-tumor Activity of the Type I PRMT Inhibitor, GSK3368715, Synergizes with PRMT5 Inhibition through MTAP Loss.
Andrew Fedoriw, Satyajit R Rajapurkar, Shane O'Brien, Sarah V Gerhart, Lorna H Mitchell

Cancer Cell· July 2019

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Small molecule inhibitors and CRISPR/Cas9 mutagenesis demonstrate that SMYD2 and SMYD3 activity are dispensable for autonomous cancer cell proliferation.
Michael J Thomenius, Jennifer Totman, Darren Harvey, Lorna H Mitchell, Thomas V Riera

PLoS One· December 2018

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
Identification of a peptide inhibitor for the histone methyltransferase WHSC1.
Michael J Morrison, P Ann Boriack-Sjodin, Kerren K Swinger, Tim J Wigle, Dipti Sadalge, Lorna H Mitchell

PLoS One· August 2018

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
M
Methionine sulfoxide reductase B3 requires resolving cysteine residues for full activity and can act as a stereospecific methionine oxidase.
Zhenbo Cao, Lorna Mitchell, Oliver Hsia, Miriam Scarpa, Stuart T Caldwell

Biochem J· February 2018

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
Identification of a CARM1 Inhibitor with Potent In Vitro and In Vivo Activity in Preclinical Models of Multiple Myeloma.
Allison E Drew, Oscar Moradei, Suzanne L Jacques, Nathalie Rioux, Ann P Boriack-Sjodin, Lorna H Mitchell

Sci Rep· December 2017

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
G
GHSI EMERGENCY RADIONUCLIDE BIOASSAY LABORATORY NETWORK - SUMMARY OF THE SECOND EXERCISE.
Chunsheng Li, Christine Bartizel, Paolo Battisti, Axel Böttger, Céline Bouvier, Lorna Mitchell

Radiat Prot Dosimetry· May 2017

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
The membrane topology of vitamin K epoxide reductase is conserved between human isoforms and the bacterial enzyme.
Zhenbo Cao, Marcel van Lith, Lorna J Mitchell, Marie Anne Pringle, Kenji Inaba

Biochem J· April 2016

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
N
Novel Oxindole Sulfonamides and Sulfamides: EPZ031686, the First Orally Bioavailable Small Molecule SMYD3 Inhibitor.
Lorna H Mitchell, P Ann Boriack-Sjodin, Sherri Smith, Michael Thomenius, Nathalie Rioux

ACS Med Chem Lett· February 2016

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Structural and Kinetic Characterization of a Novel N-acetylated Aliphatic Amine Metabolite of the PRMT Inhibitor, EPZ011652.
Nathalie Rioux, Lorna H Mitchell, Philip Tiller, Katie Plant, Joanne Shaw

Drug Metab Dispos· July 2015

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
Aryl Pyrazoles as Potent Inhibitors of Arginine Methyltransferases: Identification of the First PRMT6 Tool Compound.
Lorna H Mitchell, Allison E Drew, Scott A Ribich, Nathalie Rioux, Kerren K Swinger

ACS Med Chem Lett· June 2015

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Solar photochemical oxidation of alcohols using catalytic hydroquinone and copper nanoparticles under oxygen: oxidative cleavage of lignin models.
Lorna J Mitchell, Christopher J Moody

J Org Chem· November 2014

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Studies Culminating in the Total Synthesis and Determination of the Absolute Configuration of (-)-Saudin.
Robert K Boeckman, Maria Rico Del Rosario Ferreira, Lorna H Mitchell, Pengcheng Shao, Michael J Neeb

Tetrahedron· December 2011

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
Identification of cells expressing IL-17A and IL-17F in the lungs of patients with COPD.
Amanda Eustace, Lucy J C Smyth, Lorna Mitchell, Kate Williamson, Jonathan Plumb

Chest· May 2011

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
R
Rational design of a topical androgen receptor antagonist for the suppression of sebum production with properties suitable for follicular delivery.
Lorna H Mitchell, Theodore R Johnson, Guang Wei Lu, Daniel Du, Kaushik Datta

J Med Chem· June 2010

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
Thyroid receptor agonists for the treatment of androgenetic alopecia.
Jie Jack Li, Lorna H Mitchell, Robert L Dow

Bioorg Med Chem Lett· January 2010

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Diphenyl ethers as androgen receptor antagonists for the topical suppression of sebum production.
Lorna H Mitchell, Lain-Yen Hu, Maria Nguyen, Stephen Fakhoury, Yvonne Smith

Bioorg Med Chem Lett· April 2009

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
4
4-(Alkylthio)- and 4-(arylthio)-benzonitrile derivatives as androgen receptor antagonists for the topical suppression of sebum production.
Lorna Mitchell, Zhi Wang, Lain-Yen Hu, Catherine Kostlan, Matthew Carroll

Bioorg Med Chem Lett· March 2009

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
(
(1R,2S)-4-(2-cyano-cyclohexyl-oxy)-2-trifluoromethyl-benzonitrile, a potent androgen receptor antagonist for stimulating hair growth and reducing sebum production.
Lain-Yen Hu, Daniel Du, Jennifer Hoffman, Yvonne Smith, Victor Fedij, Lorna Mitchell

Bioorg Med Chem Lett· November 2007

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
P
Preparation of 4-aryl-2-trifluoromethylbenzonitrile derivatives as androgen receptor antagonists for topical suppression of sebum production.
Jennifer A Van Camp, Lain-Yen Hu, Catherine Kostlan, Bruce Lefker, Jie Li, Lorna Mitchell

Bioorg Med Chem Lett· October 2007

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
A practical Buchwald-Hartwig amination of 2-bromopyridines with volatile amines.
Jie Jack Li, Zhi Wang, Lorna H Mitchell

J Org Chem· April 2007

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
4
4-Phenylpyrrolo[3,4-c]carbazole-1,3(2H,6H)-dione inhibitors of the checkpoint kinase Wee1. Structure-activity relationships for chromophore modification and phenyl ring substitution.
Brian D Palmer, Andrew M Thompson, R John Booth, Ellen M Dobrusin, Alan J Kraker, Lorna H Mitchell

J Med Chem· August 2006

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
An enantioselective total synthesis of (+)- and (-)-saudin. Determination of the absolute configuration.
Robert K Boeckman, Maria del Rosario Rico Ferreira, Lorna H Mitchell, Pengcheng Shao

J Am Chem Soc· January 2002

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis