Publications by authors named "Stuart Ellison"

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Systemic immune challenge exacerbates neurodegeneration in a model of neurological lysosomal disease.
Oriana Mandolfo, Helen Parker, Èlia Aguado, Yuko Ishikawa Learmonth, Ai Yin Liao, Stuart Ellison

EMBO Mol Med· July 2024

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Design and validation of a GMP stem cell manufacturing protocol for MPSII hematopoietic stem cell gene therapy.
Stuart Ellison, Karen Buckland, Yuko Learmonth, Victoria Day, Spandan Kalra

Mol Ther Methods Clin Dev· June 2024

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Fusion of Rabies Virus Glycoprotein or gh625 to Iduronate-2-Sulfatase for the Treatment of Mucopolysaccharidosis Type II.
Shaun R Wood, Ahsan Chaudrhy, Stuart Ellison, Rachel Searle, Constance Burgod

Hum Gene Ther· April 2024

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Optimised protocols to generate high titre lentiviral vectors using a novel transfection agent enabling extended HEK293T culture following transient transfection and suspension culture.
Saqlain Suleman, Serena Fawaz, Terry Roberts, Stuart Ellison, Brian Bigger

J Virol Methods· April 2024

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Sustained long-term disease correction in a murine model of MPSII following stem cell gene therapy.
Stuart Ellison, Aiyin Liao, Hélène F E Gleitz, Helen Parker, Laura Booth

Mol Ther Methods Clin Dev· December 2023

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Actinomycin D downregulates Sox2 and improves survival in preclinical models of recurrent glioblastoma.
Jessica T Taylor, Stuart Ellison, Alina Pandele, Shaun Wood, Erica Nathan

Neuro Oncol· September 2020

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Haematopoietic stem cell gene therapy with IL-1Ra rescues cognitive loss in mucopolysaccharidosis IIIA.
Helen Parker, Stuart M Ellison, Rebecca J Holley, Claire O'Leary, Aiyin Liao

EMBO Mol Med· March 2020

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Pre-clinical Safety and Efficacy of Lentiviral Vector-Mediated Stem Cell Gene Therapy for the Treatment of Mucopolysaccharidosis IIIA.
Stuart M Ellison, Aiyin Liao, Shaun Wood, Jessica Taylor, Amir Saam Youshani

Mol Ther Methods Clin Dev· June 2019

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Macrophage enzyme and reduced inflammation drive brain correction of mucopolysaccharidosis IIIB by stem cell gene therapy.
Rebecca J Holley, Stuart M Ellison, Daniel Fil, Claire O'Leary, John McDermott

Brain· January 2018

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Vesicular stomatitis virus glycoprotein- and Venezuelan equine encephalitis virus-derived glycoprotein-pseudotyped lentivirus vectors differentially transduce corneal endothelium, trabecular meshwork, and human photoreceptors.
Daniel M Lipinski, Alun R Barnard, Peter Charbel Issa, Mandeep S Singh, Samantha R De Silva, Stuart M Ellison

Hum Gene Ther· January 2014

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Dose-dependent neuroprotection of VEGF₁₆₅ in Huntington's disease striatum.
Stuart M Ellison, Antonio Trabalza, Veronica Tisato, Evangelos Pazarentzos, Shirley Lee

Mol Ther· October 2013

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Dominant role of the protein-tyrosine phosphatase CD148 in regulating platelet activation relative to protein-tyrosine phosphatase-1B.
Jun Mori, Ying-Jie Wang, Stuart Ellison, Silke Heising, Benjamin G Neel

Arterioscler Thromb Vasc Biol· December 2012

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The tyrosine phosphatase CD148 is an essential positive regulator of platelet activation and thrombosis.
Yotis A Senis, Michael G Tomlinson, Stuart Ellison, Alexandra Mazharian, Jenson Lim

Blood· May 2009

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Genetic loci contributing to hemophagocytic lymphohistiocytosis do not confer susceptibility to systemic-onset juvenile idiopathic arthritis.
Rachelle Donn, Stuart Ellison, Rebecca Lamb, Thomas Day, Eileen Baildam

Arthritis Rheum· March 2008

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Human macrophage migration inhibitory factor: a proven immunomodulatory cytokine?
Alex Kudrin, Martin Scott, Steven Martin, Chun-Wa Chung, Rachelle Donn, Stuart Ellison

J Biol Chem· October 2006

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