Publications by authors named "Stuart Mannering"

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Structure and dynamics of GAD65 in complex with an autoimmune polyendocrine syndrome type 2-associated autoantibody.
Susanne H D Ständer, Cyril F Reboul, Sarah N Le, Daniel E Williams, Peter G Chandler, Stuart I Mannering

Nat Commun· March 2025

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BASTA, a simple whole-blood assay for measuring β cell antigen-specific CD4 T cell responses in type 1 diabetes.
Matthew Lacorcia, Pushpak Bhattacharjee, Abby Foster, Melinda Y Hardy, Jason A Tye-Din, Stuart I Mannering

Sci Transl Med· March 2025

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Current and Emerging Assays for Measuring Human T-Cell Responses Against Beta-Cell Antigens in Type 1 Diabetes.
Ting-Chen Lin, Matthew Lacorcia, Stuart I Mannering

Biomolecules· March 2025

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A minority of proliferating human CD4 T cells in antigen-driven proliferation assays are antigen specific.
Pushpak Bhattacharjee, Miha Pakusch, Matthew Lacorcia, Chris Y Chiu, Xin Liu, Stuart I Mannering

Front Immunol· November 2024

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Proinsulin C-peptide is a major source of HLA-DQ8 restricted hybrid insulin peptides recognized by human islet-infiltrating CD4 T cells.
Pushpak Bhattacharjee, Miha Pakusch, Matthew Lacorcia, Eleonora Tresoldi, Alan F Rubin, Stuart I Mannering

PNAS Nexus· November 2024

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A structural basis of T cell cross-reactivity to native and spliced self-antigens presented by HLA-DQ8.
Mai T Tran, Jia Jia Lim, Tiing Jen Loh, Stuart I Mannering, Jamie Rossjohn

J Biol Chem· September 2024

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HLA-DQ8 Supports Development of Insulitis Mediated by Insulin-Reactive Human TCR-Transgenic T Cells in Nonobese Diabetic Mice.
Jeremy J Racine, Adel Misherghi, Jennifer R Dwyer, Richard Maser, Elvira Forte, Stuart Mannering

J Immunol· December 2023

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Monitoring immunomodulation strategies in type 1 diabetes.
Balasubramanian Krishnamurthy, Matthew Lacorcia, Thomas W H Kay, Helen E Thomas, Stuart I Mannering

Front Immunol· June 2023

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Glutamine deamidation does not increase the immunogenicity of C-peptide in people with type 1 diabetes.
Abby Foster, Pushpak Bhattacharjee, Eleonora Tresoldi, Miha Pakusch, Fergus J Cameron, Stuart I Mannering

J Transl Autoimmun· December 2022

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Modeling Type 1 Diabetes Using Pluripotent Stem Cell Technology.
Kriti Joshi, Fergus Cameron, Swasti Tiwari, Stuart I Mannering, Andrew G Elefanty

Front Endocrinol (Lausanne)· December 2021

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Identifying New Hybrid Insulin Peptides (HIPs) in Type 1 Diabetes.
Stuart I Mannering, Alan F Rubin, Ruike Wang, Pushpak Bhattacharjee

Front Immunol· October 2021

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T cell receptor recognition of hybrid insulin peptides bound to HLA-DQ8.
Mai T Tran, Pouya Faridi, Jia Jia Lim, Yi Tian Ting, Goodluck Onwukwe, Stuart I Mannering

Nat Commun· August 2021

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Insulin's other life: an autoantigen in type 1 diabetes.
Stuart I Mannering, Pushpak Bhattacharjee

Immunol Cell Biol· May 2021

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CD8 T cell landscape in Indigenous and non-Indigenous people restricted by influenza mortality-associated HLA-A*24:02 allomorph.
Luca Hensen, Patricia T Illing, E Bridie Clemens, Thi H O Nguyen, Marios Koutsakos, Stuart I Mannering

Nat Commun· May 2021

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Unresponsiveness to inhaled antigen is governed by conventional dendritic cells and overridden during infection by monocytes.
James G Bedford, Melanie Heinlein, Alexandra L Garnham, Thi H O Nguyen, Tom Loudovaris, Stuart I Mannering

Sci Immunol· October 2020

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HLA-B*27:05 alters immunodominance hierarchy of universal influenza-specific CD8+ T cells.
Sneha Sant, Sergio M Quiñones-Parra, Marios Koutsakos, Emma J Grant, Thomas Loudovaris, Stuart I Mannering

PLoS Pathog· August 2020

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Replacing murine insulin 1 with human insulin protects NOD mice from diabetes.
Colleen M Elso, Nicholas A Scott, Lina Mariana, Emma I Masterman, Andrew P R Sutherland, Stuart I Mannering

PLoS One· March 2020

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Induced pluripotent stem cell macrophages present antigen to proinsulin-specific T cell receptors from donor-matched islet-infiltrating T cells in type 1 diabetes.
Kriti Joshi, Colleen Elso, Ali Motazedian, Tanya Labonne, Jacqueline V Schiesser, Stuart I Mannering

Diabetologia· December 2019

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IFNγ-Induced MHC Class II Expression on Islet Endothelial Cells Is an Early Marker of Insulitis but Is Not Required for Diabetogenic CD4 T Cell Migration.
Nicholas A Scott, Yuxing Zhao, Balasubramanian Krishnamurthy, Stuart I Mannering, Thomas W H Kay

Front Immunol· October 2019

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Human γδ T-cell receptor repertoire is shaped by influenza viruses, age and tissue compartmentalisation.
Sneha Sant, Misty R Jenkins, Pradyot Dash, Katherine A Watson, Zhongfang Wang, Stuart I Mannering

Clin Transl Immunology· September 2019

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Standardizing T-Cell Biomarkers in Type 1 Diabetes: Challenges and Recent Advances.
Simi Ahmed, Karen Cerosaletti, Eddie James, S Alice Long, Stuart Mannering

Diabetes· July 2019

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Quantification of Proliferating Human Antigen-specific CD4+ T Cells using Carboxyfluorescein Succinimidyl Ester.
Anthony R Di Carluccio, Eleonora Tresoldi, Michelle So, Stuart I Mannering

J Vis Exp· June 2019

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Human CD8 T cell cross-reactivity across influenza A, B and C viruses.
Marios Koutsakos, Patricia T Illing, Thi H O Nguyen, Nicole A Mifsud, Jeremy Chase Crawford, Stuart I Mannering

Nat Immunol· May 2019

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Divergent SATB1 expression across human life span and tissue compartments.
Simone Nüssing, Hui-Fern Koay, Sneha Sant, Thomas Loudovaris, Stuart I Mannering

Immunol Cell Biol· May 2019

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Neoepitopes: a new take on beta cell autoimmunity in type 1 diabetes.
Stuart I Mannering, Anthony R Di Carluccio, Colleen M Elso

Diabetologia· March 2019

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