Publications by authors named "Sudarshan Murthy"

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Binding Differences of the Peptide-Substrate-Binding Domain of Collagen Prolyl 4-Hydroxylases I and II for Proline- and Hydroxyproline-Rich Peptides.
M Mubinur Rahman, Ramita Sulu, Bukunmi Adediran, Hongmin Tu, Antti M Salo, Sudarshan Murthy

Proteins· October 2025

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High-Throughput Exonuclease Assay Based on the Fluorescent Base Analogue 2-Aminopurine.
Margherita M Botto, Sudarshan Murthy, Meindert H Lamers

ACS Omega· March 2023

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[1,2,4]Triazolo[3,4-]benzothiazole Scaffold as Versatile Nicotinamide Mimic Allowing Nanomolar Inhibition of Different PARP Enzymes.
Sudarshan Murthy, Maria Giulia Nizi, Mirko M Maksimainen, Serena Massari, Juho Alaviuhkola

J Med Chem· January 2023

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Potent 2,3-dihydrophthalazine-1,4-dione derivatives as dual inhibitors for mono-ADP-ribosyltransferases PARP10 and PARP15.
Maria Giulia Nizi, Mirko M Maksimainen, Sudarshan Murthy, Serena Massari, Juho Alaviuhkola

Eur J Med Chem· July 2022

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Analogs of TIQ-A as inhibitors of human mono-ADP-ribosylating PARPs.
Mirko M Maksimainen, Sudarshan Murthy, Sven T Sowa, Albert Galera-Prat, Elena Rolina

Bioorg Med Chem· December 2021

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Development of a 1,2,4-Triazole-Based Lead Tankyrase Inhibitor: Part II.
Ruben G G Leenders, Shoshy Alam Brinch, Sven T Sowa, Enya Amundsen-Isaksen, Albert Galera-Prat, Sudarshan Murthy

J Med Chem· December 2021

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Evaluation of 3- and 4-Phenoxybenzamides as Selective Inhibitors of the Mono-ADP-Ribosyltransferase PARP10.
Patricia Korn, Arno Classen, Sudarshan Murthy, Riccardo Guareschi, Mirko M Maksimainen

ChemistryOpen· October 2021

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IceBear: an intuitive and versatile web application for research-data tracking from crystallization experiment to PDB deposition.
Ed Daniel, Mirko M Maksimainen, Neil Smith, Ville Ratas, Ekaterina Biterova, Sudarshan N Murthy

Acta Crystallogr D Struct Biol· February 2021

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Preclinical Lead Optimization of a 1,2,4-Triazole Based Tankyrase Inhibitor.
Jo Waaler, Ruben G G Leenders, Sven T Sowa, Shoshy Alam Brinch, Max Lycke, Sudarshan Murthy

J Med Chem· July 2020

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Small-Molecule Screening Assay for Mono-ADP-Ribosyltransferases.
Teemu Haikarainen, Sudarshan Murthy, Mirko M Maksimainen, Lari Lehtiö

Methods Mol Biol· March 2019

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4-(Phenoxy) and 4-(benzyloxy)benzamides as potent and selective inhibitors of mono-ADP-ribosyltransferase PARP10/ARTD10.
Sudarshan Murthy, Jenny Desantis, Patricia Verheugd, Mirko M Maksimainen, Harikanth Venkannagari

Eur J Med Chem· August 2018

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2-Phenylquinazolinones as dual-activity tankyrase-kinase inhibitors.
Yves Nkizinkiko, Jenny Desantis, Jarkko Koivunen, Teemu Haikarainen, Sudarshan Murthy

Sci Rep· January 2018

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Discovery of a Novel Series of Tankyrase Inhibitors by a Hybridization Approach.
Upendra Rao Anumala, Jo Waaler, Yves Nkizinkiko, Alexander Ignatev, Katina Lazarow, Sudarshan Murthy

J Med Chem· December 2017

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Highly Potent and Isoform Selective Dual Site Binding Tankyrase/Wnt Signaling Inhibitors That Increase Cellular Glucose Uptake and Have Antiproliferative Activity.
Amit Nathubhai, Teemu Haikarainen, Jarkko Koivunen, Sudarshan Murthy, Françoise Koumanov

J Med Chem· January 2017

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